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Adult males were irradiated with 50Gy of gamma radiation, and changes in the expression of proteins in SDS-PAGE gel bands corresponding to molecular weights ~60\u201375kDa and ~80\u201395kDa were analyzed at two different time points 6 and 12-hour post-irradiation, using a temporal mass spectrometry based semi-quantitative analysis. A 2-3-fold increase was observed in both proteins Hsc70 and Hsp83, at both time points. In addition, the experiment also revealed the overexpression of several other molecules such as Arginine Kinase - known to be upregulated in certain insects during stress, Esterase B1- implicated in insecticide resistance, and also down-regulation of the 26S proteasome non-ATPase regulatory subunit 1 and ubiquitin-activating enzyme E1 - both known to be involved in ubiquitin-mediated protein degradation. The results taken together with existing data on Hsp83 and Hsc70, indicate that these proteins may enhance the survival of\n                      <jats:italic toggle=\"yes\">Ae. aegypti<\/jats:italic>\n                      following gamma radiation and could serve as molecular markers for the detection of radiation-induced stress.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/0972-9062.335770","type":"journal-article","created":{"date-parts":[[2022,1,13]],"date-time":"2022-01-13T06:43:51Z","timestamp":1642056231000},"page":"145-153","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Gamma radiation induced changes in expression of heat shock proteins (Hsc70 and Hsp83) in the dengue vector Aedes aegypti (L.)"],"prefix":"10.4103","volume":"59","author":[{"given":"Vinaya","family":"Shetty","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N. 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