{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:32:22Z","timestamp":1787758342055,"version":"build-2784847793"},"reference-count":32,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:p>\n                    Scrub typhus is a vector-borne disease caused by\n                    <jats:italic toggle=\"yes\">Orientia tsutsugamushi<\/jats:italic>\n                    , propagated into humans by the bite of infected mite belonging to genus\n                    <jats:italic toggle=\"yes\">Leptotrombodium<\/jats:italic>\n                    . The present study was conducted in the Nagpur region of central India aiming towards a survey of cohabiting rodents and their potential vectors for the presence of\n                    <jats:italic toggle=\"yes\">Orientia tsutsugamushi<\/jats:italic>\n                    by PCR method. The study also emphasizes serological diagnosis of the disease by employing indirect IgM ELISA and IFA amongst the human cases of pyrexia of unknown origin. Indirect IgM ELISA recorded 39.69% (31\/92) seropositive patients, further processing of ELISA positive samples for IFA revealed 67.74 % (21\/31) positivity for Boryong, Gilliam, Karp, and Kato serotypes. A total of 50 rodents were trapped from the cohabit areas of the patients. Three different types of rodents were identified; among which,\n                    <jats:italic toggle=\"yes\">Rattus bandicoot<\/jats:italic>\n                    was highest. From these rodents, 164 vectors\n                    <jats:italic toggle=\"yes\">viz<\/jats:italic>\n                    mites, lice, and fleas were collected. The highest chiggar index was recorded for\n                    <jats:italic toggle=\"yes\">Ornithonyssus biscotti<\/jats:italic>\n                    mites (3.4). This study prompts a detailed analysis of different species of rodents and vectors in the said endemic region.\n                  <\/jats:p>","DOI":"10.4103\/0972-9062.355964","type":"journal-article","created":{"date-parts":[[2022,9,12]],"date-time":"2022-09-12T08:29:55Z","timestamp":1662971395000},"page":"244-251","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Edifications on Indirect IgM ELISA and Immunofluorescence assay (IFA) of scrub typhus in humans and erudition of Orientia tsutsugamushi in the vector of cohabiting rodents"],"prefix":"10.4103","volume":"60","author":[{"given":"Shubham","family":"Patil","sequence":"first","affiliation":[{"name":"Department of Veterinary Public Health, Nagpur Veterinary College, Nagpur, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Archana","family":"Patil","sequence":"additional","affiliation":[{"name":"Department of Veterinary Public Health, Nagpur Veterinary College, Nagpur, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandip","family":"Chaudhari","sequence":"additional","affiliation":[{"name":"Department of Veterinary Public Health, Nagpur Veterinary College, Nagpur, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shilpshri","family":"Shinde","sequence":"additional","affiliation":[{"name":"Department of Veterinary Public Health, Nagpur Veterinary College, Nagpur, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunil","family":"Kolte","sequence":"additional","affiliation":[{"name":"Department of Veterinary Parasitology, Nagpur Veterinary College, Nagpur, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Waqar","family":"Khan","sequence":"additional","affiliation":[{"name":"Department of Veterinary Public Health, Nagpur Veterinary College, Nagpur, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nitin","family":"Kurkure","sequence":"additional","affiliation":[{"name":"Maharashtra Animal and Fishery Sciences University, Nagpur, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,10,6]]},"reference":[{"issue":"1","key":"R1-20240830","doi-asserted-by":"crossref","first-page":"8","DOI":"10.3390\/tropicalmed3010008","article-title":"A Review of Scrub Typhus (Orientia tsutsugamushi and Related Organisms): Then, Now, and Tomorrow","volume":"3","author":"Luce-Fedrow","year":"2018","journal-title":"Trop Med Infect Dis"},{"issue":"6","key":"R2-20240830","doi-asserted-by":"crossref","first-page":"e66595","DOI":"10.1371\/journal.pone.0066595","article-title":"Scrub Typhus Meningitis in South India - A Retrospective Study.","volume":"8","author":"Viswanathan","year":"2013","journal-title":"PLoS One"},{"key":"R3-20240830","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1111\/j.1749-6632.2003.tb07391.x","article-title":"Outbreak of scrub typhus in southern India during the cooler months.","volume":"990","author":"Mathai","year":"2003","journal-title":"Ann N Y Acad Sci"},{"key":"R4-20240830","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1086\/424748","article-title":"Scrub typhus: prevalence and diagnostic issues in rural Southern India.","volume":"39","author":"Isaac","year":"2004","journal-title":"Clin Infect Dis"},{"key":"R5-20240830","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1007\/s10661-019-7208-7","article-title":"Distribution of Orientia tsutsugamushi in rodents and mites collected from Central India","volume":"191","author":"Batul","year":"2019","journal-title":"Environ Monit Assess"},{"key":"R6-20240830","article-title":"Scenario of Orientia tsutsugamushi Infection in Human and Rodent in around Nagpur. 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