{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:28:08Z","timestamp":1787761688481,"version":"build-2784847793"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>\n                      <jats:italic toggle=\"yes\">Background &amp; objectives<\/jats:italic>\n                      : Japanese encephalitis (JE) is a major public health problem in India. The first outbreaks of JE have been reported from the North-eastern regions of Assam, particularly from the Lakhimpur district of Assam between July\u2013August 1989. In Assam every year many people died due to JE. This study was performed to investigate the molecular epidemiology of JE in pigs in Lakhimpur district of Assam and the risk factors associated with causing Japanese encephalitis in pigs. This study will help to map out the endemic regions and to know where and when to apply the most control strategies towards the prevention and control of the disease.\n                    <\/jats:p>\n                    <jats:p>\n                      <jats:italic toggle=\"yes\">Methods<\/jats:italic>\n                      : A total of 342 serum samples from pigs were collected from 10 organized and 20 unorganized farms from 9 blocks and recorded to age, sex and breed and tested by RT-PCR. Pig farms and the surrounding environment were studied for assessment of farm-level risk factors responsible for JEV infection in pigs.\n                    <\/jats:p>\n                    <jats:p>\n                      <jats:italic toggle=\"yes\">Results<\/jats:italic>\n                      : Out of 342 samples tested for detection of the\n                      <jats:italic toggle=\"yes\">E gene<\/jats:italic>\n                      of JEV, 14 samples were found to be positive with a prevalence rate of 4.09%. Age, sex and breed-wise higher cases were found in at the age group above 12 months, sex wise female and breed-wise local pigs. Pig farms less than 500 meters from risk factors like rice field, stagnant water source, wild bird exposure to farm and mosquito exposure at farm\/ bite to pigs, found to be more numbers of JE cases.\n                    <\/jats:p>\n                    <jats:p>\n                      <jats:italic toggle=\"yes\">Interpretation &amp; conclusion<\/jats:italic>\n                      : Molecular epidemiology of JE in pigs, and humans; positive at Lakhimpur recommend the need for uninterrupted surveillance of this virus in pigs specially those areas where pig population is more and all risk factors are present.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/0972-9062.355966","type":"journal-article","created":{"date-parts":[[2022,9,12]],"date-time":"2022-09-12T08:29:55Z","timestamp":1662971395000},"page":"356-362","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["Molecular epidemiology of Japanese encephalitis in pigs and risk factors associated with causing Japanese encephalitis in pigs of Lakhimpur, the first case reported in the district of North East India"],"prefix":"10.4103","volume":"59","author":[{"given":"U","family":"Rajkhowa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"AG","family":"Barua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D","family":"Malakar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-7-20240830","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1002\/ajmg.a.33891","article-title":"A new micro deletion syndrome of 5q31.3 characterized by severe developmental delays, distinctive facial features, and delayed myelination","volume":"155","author":"Shimojima","year":"2011","journal-title":"Amcn Jnl Med Genet"},{"key":"R3-7-20240830","first-page":"95","article-title":"Economic burden of malaria in India: the need for effective spending. WHO South-East","volume":"3","author":"Gupta","year":"2014","journal-title":"Asia J Public Health"},{"key":"R4-7-20240830","first-page":"481","article-title":"World Health Day an opportunity to promote research on vectors & vector-borne diseases","volume":"139","author":"Ortega","year":"2014","journal-title":"Indian J Med Res"},{"key":"R5-7-20240830","doi-asserted-by":"crossref","first-page":"766","DOI":"10.2471\/BLT.10.085233","article-title":"Estimated global incidence of Japanese encephalitis: A systematic review","volume":"89","author":"Campbell","year":"2011","journal-title":"Bull Wld Hlth Organ"},{"key":"R6-7-20240830","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/S0188-4409(02)00378-8","article-title":"The global emergence\/resurgence of arboviral diseases as public health problem","volume":"33","author":"Gubler","year":"2002","journal-title":"Archives Med Res"},{"key":"R8-7-20240830","first-page":"177","article-title":"Emerging viral infections with special reference to India","volume":"103","author":"Banerjee","year":"1996","journal-title":"Indian J Med Res"},{"key":"R9-7-20240830","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1007\/BF02724120","article-title":"Japanese encephalitis in India: an overview","volume":"71","author":"Kabilan","year":"2004","journal-title":"Indian J Prediarices"},{"key":"R10-7-20240830","doi-asserted-by":"crossref","first-page":"104325","DOI":"10.1016\/j.meegid.2020.104325","article-title":"Molecular epidemiology of Japanese encephalitis virus in pig population of Odisha, Assam and Manipur states of India","volume":"83","author":"Datey","year":"2020","journal-title":"Infection, Genetics and Evolution"},{"key":"R11-7-20240830","doi-asserted-by":"crossref","first-page":"3490","DOI":"10.18203\/2320-6012.ijrms20193934","article-title":"Seroprevalence of Japanese encephalitis amongst cases ofacute encephalitis syndrome in a tertiary care centre of north east India: a four year retrospective study","volume":"7","author":"Mohan","year":"2019","journal-title":"Int J Res Med Sci"},{"key":"R12-7-20240830","doi-asserted-by":"crossref","first-page":"11784","DOI":"10.1038\/s41598-018-30054-z","article-title":"PLVAP and GKN3 are two critical host cell receptors which facilitate Japanese encephalitis virus entry into neurons","volume":"8","author":"Mukherjee","year":"2018","journal-title":"Sci Rep"},{"key":"R13-7-20240830","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1111\/j.1863-2378.2012.01456.x","article-title":"Seroprevalence of Japanese encephalitis virus and risk factors associated with seropositivity in pigs in four mountain districts in Nepal","volume":"59","author":"Thakur","year":"2012","journal-title":"Zoonoses Public Health"},{"key":"R14-7-20240830","first-page":"65","article-title":"Seasonal sero-prevalence of Japanese encephalitis in swine using indirect ELISA","volume":"2","author":"Dhanze","year":"2014","journal-title":"J Vet Pub Hlth"},{"key":"R15-7-20240830","first-page":"273","article-title":"Isolation of Japanese encephalitis virus from sentinel domestic pig from Kolar district in Karnataka","volume":"86","author":"Geeverghese","year":"1987","journal-title":"Indian J Med Res"},{"key":"R16-7-20240830","doi-asserted-by":"crossref","first-page":"311","DOI":"10.3126\/ijasbt.v2i3.10639","article-title":"Pig sero-survey and farm level risk factor assessment for Japanese encephalitis in Nepal","volume":"2","author":"Ghimire","year":"2014","journal-title":"Int J Appl Sci Biotechnol"},{"key":"R17-7-20240830","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1146\/annurev.ento.54.110807.090510","article-title":"Ecological and geographical expansion of Japanese encephalitis virus","volume":"54","author":"Hurk","year":"2009","journal-title":"Annu Rev Entomol"},{"key":"R18-7-20240830","first-page":"618","article-title":"Japanese encephalitis in Assam, Northeast India","volume":"35","author":"Phukan","year":"2004","journal-title":"Southeast Asian J Trop Med Public Health"},{"key":"R19-7-20240830","first-page":"104","article-title":"Long-term study on vector abundance and seasonal prevalence in relation to the occurrence of Japanese encephalitis in Gorakhpur district, Uttar Pradesh","volume":"117","author":"Kanojia","year":"2003","journal-title":"Indian J Med Res"},{"key":"R20-7-20240830","first-page":"24","article-title":"Standardization of Indirect ELISA for sero-diagnosis of Japanese encephalitis in Guinea fowl and chicken","volume":"1","author":"Kohle","year":"2011","journal-title":"Current Research in Poultry Science"},{"key":"R21-7-20240830","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1099\/vir.0.79797-0","article-title":"Shift in Japanese encephalitis virus (JEV) genotype circulating in Northern Vietnam: implications for frequent introductions of JEV from Southeast Asia to East Asia","volume":"85","author":"Nga","year":"2004","journal-title":"J Gen Virol"},{"key":"R22-7-20240830","first-page":"382","article-title":"Role of some environmental factors in modulating seasonal abundance of potential Japanese encephalitis vectors in Assam, India","volume":"27","author":"Khan","year":"1996","journal-title":"Southeast Asian J Trop Med Public Health"}],"container-title":["Journal of Vector Borne Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/0972-9062.355966","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:04:07Z","timestamp":1787760247000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/0972-9062.355966"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":20,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/0972-9062.355966","relation":{},"ISSN":["0972-9062"],"issn-type":[{"value":"0972-9062","type":"print"}],"subject":[],"published":{"date-parts":[[2022,10]]}}}