{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:43:42Z","timestamp":1787071422924,"version":"build-2736575974"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2012,9]]},"abstract":"<jats:p>The granular enlargement of the gingiva may be the first clinical manifestation of Orofacial granulomatosis, preceding other local or systemic manifestations. The term Idiopathic Orofacial granulomatosis (OFG) refers to conditions restricted to the oral region without any identifiable systemic granulomatous diseases. We report a case of nine year old female patient with gingival enlargement as the sole manifestation without any systemic involvement. Laboratory investigations were done to rule out tuberculosis, sarcoidosis, allergic hypersensitivity, Crohn's disease. The patient was treated by gingivectomy and there is complete remission of the lesion without any recurrence. Thus the early investigations and diagnosis of OFG can help in the prevention of future systemic complications.<\/jats:p>","DOI":"10.4103\/0973-029x.102510","type":"journal-article","created":{"date-parts":[[2012,10,16]],"date-time":"2012-10-16T03:43:20Z","timestamp":1350359000000},"page":"432-434","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Idiopathic orofacial granulomatosis in a young patient: A rare entity"],"prefix":"10.4103","volume":"16","author":[{"given":"Gurumoorthy","family":"Kaarthikeyan","sequence":"first","affiliation":[{"name":"Department of Periodontics, Saveetha Dental College, Chennai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Arvind","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine, Saveetha Dental College, Chennai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ND","family":"Jayakumar","sequence":"additional","affiliation":[{"name":"Department of Periodontics, Saveetha Dental College, Chennai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mihir","family":"Khakar","sequence":"additional","affiliation":[{"name":"Department of Periodontics, Saveetha Dental College, Chennai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20250922","first-page":"101","article-title":"Oro-facial granulomatosis--a clinical and pathological analysis","volume":"54","author":"Wiesenfeld","year":"1985","journal-title":"Q J Med"},{"key":"R2-20250922","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1136\/gut.16.4.249","article-title":"Oral manifestations of Crohn's disease","volume":"16","author":"Asquith","year":"1975","journal-title":"Gut"},{"key":"R3-20250922","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/0002-9343(63)90165-7","article-title":"Manifestations of sarcoidosis.analysis of 145 patients, with a review of nine series selected from the literature","volume":"35","author":"Mayock","year":"1963","journal-title":"Am J Med"},{"key":"R4-20250922","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1111\/j.1600-0757.1999.tb00173.x","article-title":"Orofacial granulomatosis and related conditions","volume":"21","author":"Rees","year":"1999","journal-title":"Periodontol 2000"},{"key":"R5-20250922","first-page":"370","article-title":"Orofacial granulomatosis - 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