{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T10:56:00Z","timestamp":1791888960854,"version":"4.3.4"},"reference-count":36,"publisher":"SAGE Publications","issue":"42","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Phcog Mag"],"published-print":{"date-parts":[[2015]]},"DOI":"10.4103\/0973-1296.157743","type":"journal-article","created":{"date-parts":[[2015,6,8]],"date-time":"2015-06-08T09:08:30Z","timestamp":1433754510000},"page":"217","source":"Crossref","is-referenced-by-count":37,"title":["Pharmacological and phytochemical evaluation of Ocimum sanctum root extracts for its antiinflammatory, analgesic and antipyretic activities"],"prefix":"10.1177","volume":"11","author":[{"given":"DnyaneshwarU","family":"Bawankule","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anant","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karishma","family":"Agarwal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"AnilKumar","family":"Maurya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karuna","family":"Shanker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Umme","family":"Bushra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sudeep","family":"Tandon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","reference":[{"key":"key-10.4103\/0973-1296.157743-1","unstructured":"Burke A, Smyth E, Fitzgerald GA. Analgesic-antipyretic agents: Pharmacotherapy of gout. In: Brunton LL, Lazo JS, Parker KL, editors. Goodman and Gilmans the Pharmacological Basis of Therapeutic. New York: McGraw Hill; 2006."},{"key":"key-10.4103\/0973-1296.157743-2","first-page":"1888","volume-title":"Gastrointestinal toxicity of nonsteroidal antiinflammatory drugs","author":"Wolfe","year":"1999","journal-title":"N Engl J Med"},{"key":"key-10.4103\/0973-1296.157743-3","first-page":"215","volume-title":"Polyunsaturated fatty acids (PUFA) and eicosanoids in human health and pathologies","author":"Tapiero","year":"2002","journal-title":"Biomed Pharmacother"},{"key":"key-10.4103\/0973-1296.157743-4","first-page":"199","volume-title":"Anti-inflammatory and analgesic activities of mature fresh leaves of Vitex negundo","author":"Dharmasiri","year":"2003","journal-title":"J Ethnopharmacol"},{"key":"key-10.4103\/0973-1296.157743-5","first-page":"587","volume-title":"The protective ability of Mediterranean dietary plants against the oxidative damage: The role of radical oxygen species in inflammation and the polyphenol, flavonoid and sterol contents","author":"Conforti","year":"2009","journal-title":"Food Chem"},{"key":"key-10.4103\/0973-1296.157743-6","first-page":"323","volume-title":"Synthesis of diosgenin analogues as potential anti-inflammatory agents","author":"Singh","year":"2014","journal-title":"J Steroid Biochem Mol Biol"},{"key":"key-10.4103\/0973-1296.157743-7","first-page":"1045","volume-title":"Protective mechanism of lignans from Phyllanthus amarus against galactosamine\/lipopolysaccharide-induced hepatitis: An in-vivo and in-silico studies","author":"Bawankule","year":"2014","journal-title":"Curr Top Med Chem"},{"key":"key-10.4103\/0973-1296.157743-8","unstructured":"Warrier PK. Indian Medicinal Plants. New Delhi (India): CBS Publication; 1995. p. 168."},{"key":"key-10.4103\/0973-1296.157743-9","first-page":"121","volume-title":"Protective effect of Ocimum sanctum on ethanol-induced oxidative stress in swiss albino mice brain","author":"Bawankule","year":"2008","journal-title":"Toxicol Int","ISSN":"https:\/\/id.crossref.org\/issn\/0971-6580","issn-type":"print"},{"key":"key-10.4103\/0973-1296.157743-10","first-page":"153","volume-title":"Ocimum sanctum: An experimental study evaluating its anti-inflammatory, analgesic and antipyretic activity in animals","author":"Godhwani","year":"1987","journal-title":"J Ethnopharmacol"},{"key":"key-10.4103\/0973-1296.157743-11","first-page":"15","volume-title":"Evaluation of immunomodulatory potential of Ocimum sanctum seed oil and its possible mechanism of action","author":"Mediratta","year":"2002","journal-title":"J Ethnopharmacol"},{"key":"key-10.4103\/0973-1296.157743-12","first-page":"84","volume-title":"Hepatoprotective activity of Ocimum sanctum Linn.Against lead induced toxicity in albino rats","author":"Akilavalli","year":"2011","journal-title":"Asian J Pharm Clin Res"},{"key":"key-10.4103\/0973-1296.157743-13","first-page":"155","volume-title":"Evaluation of antioxidant and neuroprotective effect of Ocimum sanctum on transient cerebral ischemia and long-term cerebral hypoperfusion","author":"Yanpallewar","year":"2004","journal-title":"Pharmacol Biochem Behav"},{"key":"key-10.4103\/0973-1296.157743-14","first-page":"765","volume-title":"Validation of traditional claim of Tulsi, Ocimum sanctum Linn.As a medicinal plant","author":"Gupta","year":"2002","journal-title":"Indian J Exp Biol"},{"key":"key-10.4103\/0973-1296.157743-15","first-page":"51","volume-title":"Phytochemical estimation and antimicrobial activity of aqueous and methanolic extract of Ocimum sanctum L","author":"Singh","year":"2013","journal-title":"J Nat Plant Prod Plant Resour"},{"key":"key-10.4103\/0973-1296.157743-16","first-page":"497","volume-title":"In vitro anti-plasmodial activity of some traditionally used medicinal plants against Plasmodium falciparum","author":"Venkatesalu","year":"2012","journal-title":"Parasitol Res"},{"key":"key-10.4103\/0973-1296.157743-17","first-page":"120","volume-title":"Effect of Ocimum sanctum roots extract on swimming performance in mice","author":"Maity","year":"2000","journal-title":"Phytother Res"},{"key":"key-10.4103\/0973-1296.157743-18","first-page":"544","volume-title":"Carrageenin-induced edema in hind paw of the rat as an assay for antiiflammatory drugs","author":"Winter","year":"1962","journal-title":"Proc Soc Exp Biol Med"},{"key":"key-10.4103\/0973-1296.157743-19","doi-asserted-by":"crossref","unstructured":"Eddy NB, Leimbach D. Synthetic analgesics. II. Dithienylbutenyl-and dithienylbutylamines. J Pharmacol Exp Ther 1953;107:385-93.","DOI":"10.1016\/S0022-3565(25)05180-8"},{"key":"key-10.4103\/0973-1296.157743-20","first-page":"271","volume-title":"Interactions of intrathecally administered ziconotide, a selective blocker of neuronal N-type voltage-sensitive calcium channels, with morphine on nociception in rats","author":"Wang","year":"2000","journal-title":"Pain"},{"key":"key-10.4103\/0973-1296.157743-21","first-page":"521","volume-title":"The antinociceptive activity of Polygonatum verticillatum rhizomes in pain models","author":"Khan","year":"2010","journal-title":"J Ethnopharmacol"},{"key":"key-10.4103\/0973-1296.157743-22","first-page":"381","volume-title":"Further evidence for the involvement of tachykinin receptor subtypes in formalin and capsaicin models of pain in mice","author":"Santos","year":"1997","journal-title":"Neuropeptides"},{"key":"key-10.4103\/0973-1296.157743-23","first-page":"305","volume-title":"Some aspects of the pharmacology of ibufenac, a non-steroidal anti-inflammatory agent","author":"Adams","year":"1968","journal-title":"J Pharm Pharmacol"},{"key":"key-10.4103\/0973-1296.157743-24","first-page":"99","volume-title":"Safety evaluation of Trikatu, a generic Ayurvedic medicine in Charles Foster rats","author":"Chanda","year":"2009","journal-title":"J Toxicol Sci"},{"key":"key-10.4103\/0973-1296.157743-25","first-page":"61","volume-title":"Studies on anti-inflammatory, antipyretic and analgesic properties of Caesalpinia bonducella F.Seed oil in experimental animal models","author":"Shukla","year":"2010","journal-title":"Food Chem Toxicol"},{"key":"key-10.4103\/0973-1296.157743-26","first-page":"153","volume-title":"Analgesic and anti-inflammatory properties of Nelsonia canescens leaf extract","author":"Owoyele","year":"2005","journal-title":"J Ethnopharmacol"},{"key":"key-10.4103\/0973-1296.157743-27","first-page":"11","volume-title":"Anti-inflammatory and hepatoprotective effects of Ventilago leiocarpa","author":"Lin","year":"1995","journal-title":"Phytother Res"},{"key":"key-10.4103\/0973-1296.157743-28","first-page":"17","volume-title":"Release of prostaglandins E and F in an algogenic reaction and its inhibition","author":"Deraedt","year":"1980","journal-title":"Eur J Pharmacol"},{"key":"key-10.4103\/0973-1296.157743-29","first-page":"1031","volume-title":"Effect of COX-1 and COX-2 inhibition on induction and maintenance of carrageenan-evoked thermal hyperalgesia in rats","author":"Dirig","year":"1998","journal-title":"J Pharmacol Exp Ther"},{"key":"key-10.4103\/0973-1296.157743-30","first-page":"1217","volume-title":"Antinociceptive effect of the monoterpene R-(+)-limonene in mice","author":"do","year":"2007","journal-title":"Biol Pharm Bull"},{"key":"key-10.4103\/0973-1296.157743-31","first-page":"69","volume-title":"Formalin test in mice, a useful technique for evaluating mild analgesics","author":"Hunskaar","year":"1985","journal-title":"J Neurosci Methods"},{"key":"key-10.4103\/0973-1296.157743-32","first-page":"432","volume-title":"Novel 2\u2032,6\u2032- dimethyl-L-tyrosine-containing pyrazinone opioid mimetic mu-agonists with potent antinociceptive activity in mice","author":"Jinsmaa","year":"2004","journal-title":"J Pharmacol Exp Ther"},{"key":"key-10.4103\/0973-1296.157743-33","first-page":"1126","volume-title":"Analgesic, anti-inflammatory and antipyretic activities of the petroleum ether fraction from the ethanol extract of Desmodium podocarpum","author":"Zhu","year":"2011","journal-title":"J Ethnopharmacol"},{"key":"key-10.4103\/0973-1296.157743-34","first-page":"1928","volume-title":"Safety evaluation of a standardized phytochemical composition extracted from Bacopa monnieri in Sprague - Dawley rats","author":"Joshua","year":"2007","journal-title":"Food Chem Toxicol"},{"key":"key-10.4103\/0973-1296.157743-35","doi-asserted-by":"crossref","unstructured":"Mohanty S, Srivastava P, Maurya AK, Cheema HS, Shanker K, Dhawan S, et al. Antimalarial and safety evaluation of Pluchea lanceolata (DC.) Oliv. and Hiern: in-vitro and in-vivo study. J Ethnopharmacol 2013;149:797-802.","DOI":"10.1016\/j.jep.2013.08.003"},{"key":"key-10.4103\/0973-1296.157743-36","unstructured":"Berknow R. The Merck Manual of Diagnosis and Therapy. 16 th ed. New Jersey: Merck Research Laboratories Rathway; 1992. p. 1407-20."}],"container-title":["Pharmacognosy Magazine"],"original-title":[],"language":"en","deposited":{"date-parts":[[2025,5,28]],"date-time":"2025-05-28T12:11:23Z","timestamp":1748434283000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.phcog.com\/text.asp?2015\/11\/42\/217\/157743"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":36,"journal-issue":{"issue":"42","published-print":{"date-parts":[[2015]]}},"alternative-id":["157743"],"URL":"https:\/\/doi.org\/10.4103\/0973-1296.157743","relation":{},"ISSN":["0973-1296"],"issn-type":[{"value":"0973-1296","type":"print"}],"subject":[],"published":{"date-parts":[[2015]]}}}