{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T20:42:19Z","timestamp":1786653739009,"version":"build-2736575974"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>Angiosarcomas are rare malignancies with poor prognosis and could affect any organ in the body. Breast angiosarcomas mostly affect adolescent and young adult females. Here, we present the case of a 19-year-old female with low grade primary breast angiosarcoma associated with international normalized ratio (INR) abnormalities, thrombocytopenia and anemia. Patient experienced severe bleeding on biopsy. INR and count of blood cells turned to normal levels after mastectomy. Patient refused chemotherapy. Three months later, computed tomography showed liver metastasis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/0973-1482.139346","type":"journal-article","created":{"date-parts":[[2015,10,9]],"date-time":"2015-10-09T11:54:49Z","timestamp":1444391689000},"page":"655","source":"Crossref","is-referenced-by-count":0,"title":["Primary breast angiosarcoma associated with abnormalities in international normalized ratio platelet count and anemia"],"prefix":"10.4103","volume":"11","author":[{"given":"Pejva","family":"Soleymanzadeh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mostafa","family":"Hosseini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sima","family":"Karbalaei-Esmaeili","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamidreza","family":"Alizadeh-otaghvar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-76-20231126","first-page":"378","article-title":"Primary angiosarcoma of the breast: A case report and review of the literature","volume":"96","author":"Sriussadaporn","year":"2013","journal-title":"J Med Assoc Thai"},{"key":"R2-76-20231126","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1002\/jso.21497","article-title":"Primary and secondary angiosarcoma of the breast: The Mayo Clinic experience","volume":"101","author":"Scow","year":"2010","journal-title":"J Surg Oncol"},{"key":"R3-76-20231126","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.anndiagpath.2009.02.001","article-title":"Angiosarcoma of the breast: A clinicopathologic analysis of cases from the last 10 years","volume":"13","author":"Wang","year":"2009","journal-title":"Ann Diagn Pathol"},{"key":"R4-76-20231126","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S0007-1226(03)00025-0","article-title":"Angiosarcoma of the breast: A 30 year perspective with an optimistic outlook","volume":"56","author":"Georgiannos","year":"2003","journal-title":"Br J Plast Surg"},{"key":"R5-76-20231126","doi-asserted-by":"crossref","first-page":"251","DOI":"10.4174\/jkss.2012.82.4.251","article-title":"A case report of primary breast angiosarcoma with fatal pulmonary hemorrhage due to thrombocytopenia","volume":"82","author":"Kim","year":"2012","journal-title":"J Korean Surg Soc"},{"key":"R6-76-20231126","doi-asserted-by":"crossref","first-page":"193","DOI":"10.2340\/00015555-0378","article-title":"Kasabach-Merritt syndrome associated with angiosarcoma of the scalp successfully treated with chemoradiotherapy","volume":"88","author":"Imafuku","year":"2008","journal-title":"Acta Derm Venereol"},{"key":"R7-76-20231126","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.breast.2005.04.015","article-title":"Primary angiosarcoma of the breast associated Kasabach-Merritt syndrome during pregnancy","volume":"15","author":"Bernathova","year":"2006","journal-title":"Breast"},{"key":"R8-76-20231126","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1177\/030089169307900212","article-title":"Kasabach-Merritt syndrome associated to angiosarcoma of the breast. 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