{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T20:42:49Z","timestamp":1786653769908,"version":"build-2736575974"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>A rare case of xeroderma pigmentosum coexisted with keratoacanthoma in an 18-month-old boy was reported. The boy was admitted with unequal size, irregularly shaped brown spots, patches and depigmentation spots on his face. A well-circumscribed hemispherical mass measuring 3 cm \u00d7 3 cm with smooth surface and brown patches was observed beneath his left lower eyelid. Light microscopic examination of the skin lesions revealed epidermal hyperkeratosis, chronic inflammatory infiltration of the superficial dermal layer, and increases in melanocytes and melanin in the basal layer. The mass beneath the left lower eyelid was cup-shaped, consisting of proliferating squamous cells with a central keratin plug. The squamous epithelium was acanthotic with hypergranulosis. The adjacent epidermis formed exophytic projections resulting in a silhouette likened to lips. The patient was treated with a combination of antioxidant drugs, keeping the child from light and surgical excision of the mass. No recurrence has been observed.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/0973-1482.143357","type":"journal-article","created":{"date-parts":[[2015,10,9]],"date-time":"2015-10-09T11:54:49Z","timestamp":1444391689000},"page":"665","source":"Crossref","is-referenced-by-count":3,"title":["Clinicopathological characteristics of xeroderma pigmentosum associated with keratoacanthoma in an infant"],"prefix":"10.4103","volume":"11","author":[{"given":"Xu\u2032e","family":"Han","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongbiao","family":"Jing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cuijie","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinfeng","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-125-20231126","first-page":"45","article-title":"One case of xeroderma pigmentosum with a family history","volume":"41","author":"Chen","year":"2012","journal-title":"J Clin Dermatol"},{"key":"R2-125-20231126","doi-asserted-by":"crossref","first-page":"5755","DOI":"10.1128\/MCB.23.16.5755-5767.2003","article-title":"Xeroderma pigmentosum group a protein loads as a separate factor onto DNA lesions","volume":"23","author":"Rademakers","year":"2003","journal-title":"Mol Cell Biol"},{"key":"R3-125-20231126","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1093\/carcin\/bgm282","article-title":"Xeroderma pigmentosum genes: Functions inside and outside DNA repair","volume":"29","author":"Sugasawa","year":"2008","journal-title":"Carcinogenesis"},{"key":"R4-125-20231126","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1001\/archderm.1987.01660260111026","article-title":"Xeroderma pigmentosum. Cutaneous, ocular, and neurologic abnormalities in 830 published cases","volume":"123","author":"Kraemer","year":"1987","journal-title":"Arch Dermatol"},{"key":"R5-125-20231126","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1111\/j.1365-2133.2004.06311.x","article-title":"Incidence of xeroderma pigmentosum in Larkana, Pakistan: A 7-year study","volume":"152","author":"Bhutto","year":"2005","journal-title":"Br J Dermatol"},{"key":"R6-125-20231126","doi-asserted-by":"crossref","first-page":"430","DOI":"10.4103\/0378-6323.18954","article-title":"Keratoacanthoma of the conjunctiva complicating xeroderma pigmentosum","volume":"71","author":"Chowdhury","year":"2005","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"R7-125-20231126","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/S1568-7864(02)00053-8","article-title":"Polymorphisms in the human xeroderma pigmentosum group a gene and their impact on cell survival and nucleotide excision repair","volume":"1","author":"Mellon","year":"2002","journal-title":"DNA Repair (Amst"},{"key":"R8-125-20231126","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1111\/j.1365-2230.2008.02865.x","article-title":"Xeroderma pigmentosum: Early diagnostic features and an adverse consequence of photoprotection","volume":"34","author":"Ali","year":"2009","journal-title":"Clin Exp Dermatol"}],"container-title":["Journal of Cancer Research and Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/01363817-201511030-00125","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:41:54Z","timestamp":1786650114000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/01363817-201511030-00125"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":8,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015]]}},"URL":"https:\/\/doi.org\/10.4103\/0973-1482.143357","relation":{},"ISSN":["0973-1482"],"issn-type":[{"value":"0973-1482","type":"print"}],"subject":[],"published":{"date-parts":[[2015]]}}}