{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:37:40Z","timestamp":1786649860881,"version":"build-2736575974"},"reference-count":6,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2015,10]]},"abstract":"<jats:p>Choriocarcinoma is a malignant trophoblastic cancer, the incidence of primary choriocarcinoma (PCC) of the gastrointestinal tract (GIT) being extremely rare, with only 14 cases being reported in worldwide literature. Here we present an extremely rare case of PCCof the appendix in a 32-year-old male who presented with acute pain abdomen. Histopathological examination revealed PCC of the appendix. Examination of the testis was unremarkable. Further investigations revealed a very high serum beta-human chorionic gonadotropin (b-HCG) titer with a normal carcinoembryonic antigen (CEA). Radiological imaging showed multiple areas of liver metastasis. Chemotherapy-based treatment with bleomycin, etoposide, and cisplatin (BEP) regime was advised, however the patient failed to follow-up for further management.<\/jats:p>","DOI":"10.4103\/0973-1482.153663","type":"journal-article","created":{"date-parts":[[2016,2,19]],"date-time":"2016-02-19T00:48:49Z","timestamp":1455842929000},"page":"1031-1031","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Primary choriocarcinoma of appendix mimicking acute appendicitis"],"prefix":"10.4103","volume":"11","author":[{"given":"Enam Murshed","family":"Khan","sequence":"first","affiliation":[{"name":"Department of Pathology, Apollo Gleneagles Hospital, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amrita","family":"Chakrabarti","sequence":"additional","affiliation":[{"name":"Department of Pathology, Apollo Gleneagles Hospital, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amit Dutt","family":"Dwary","sequence":"additional","affiliation":[{"name":"Department of OncoMedicine, Apollo Gleneagles Hospital, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2016,2,15]]},"reference":[{"key":"R1-20260109","doi-asserted-by":"crossref","first-page":"6683","DOI":"10.3748\/wjg.v19.i39.6683","article-title":"A rare case of primary choriocarcinoma in the sigmoid colon","volume":"19","author":"Maehira","year":"2013","journal-title":"World J Gastroenterol"},{"key":"R2-20260109","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/1477-7819-11-23","article-title":"Primary choriocarcinoma of the colon: A case report and review of literature","volume":"11","author":"Jiang","year":"2013","journal-title":"World J Surg Oncol"},{"key":"R3-20260109","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/1477-7819-1-4","article-title":"Unusual presentation of choriocarcinoma","volume":"1","author":"Balagopal","year":"2003","journal-title":"World J Surg Oncol"},{"key":"R4-20260109","first-page":"44","article-title":"Unusual presentation of choriocarcinoma","volume":"14","author":"Inamullah Wasim","year":"2009","journal-title":"J Surg Pak"},{"key":"R5-20260109","first-page":"163","article-title":"Massive digestive tract hemorrhage as initial manifestation of metastatic testicular choriocarcinoma","volume":"69","author":"Alejandro","year":"2009","journal-title":"Rev Mex Urol"},{"key":"R6-20260109","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/s00595-011-0026-3","article-title":"Choriocarcinoma of the sigmoid colon: Report of a case","volume":"42","author":"Harada","year":"2012","journal-title":"Surg Today"}],"container-title":["Journal of Cancer Research and Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/01363817-201511040-00119","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T18:59:15Z","timestamp":1786647555000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/01363817-201511040-00119"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10]]},"references-count":6,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015]]}},"URL":"https:\/\/doi.org\/10.4103\/0973-1482.153663","relation":{},"ISSN":["0973-1482","1998-4138"],"issn-type":[{"value":"0973-1482","type":"print"},{"value":"1998-4138","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,10]]}}}