{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T10:04:03Z","timestamp":1787652243920,"version":"build-2736575974"},"reference-count":7,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2015,10]]},"abstract":"<jats:p>Pheochromocytoma is a tumor that has the probability to relapse in about 10% of surgically treated cases. Currently, the only recognized criteria of malignancy in these neoplasms are the evidence of metastasis at non-chromaffin sites. No reliable clinical or histopathological parameter has been, so far, identified to predict malignancy in patients with diagnosis of primary pheochromocytoma. Several authors has attempted to propose morphologic features to detect potentially malignant pheochromocytomas, but there are still too many reported cases of recurrence, also after decades, in tumors that, according to the current knowledge, are considered \"benign\". Here we report a case of recurrence, after 25 years, of a pheochromocytoma that had not enough criteria to be considered as malignant.<\/jats:p>","DOI":"10.4103\/0973-1482.154942","type":"journal-article","created":{"date-parts":[[2016,2,19]],"date-time":"2016-02-19T01:07:21Z","timestamp":1455844041000},"page":"1036-1036","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":11,"title":["Very late recurrence of an apparently benign pheochromocytoma"],"prefix":"10.4103","volume":"11","author":[{"given":"Elena","family":"Thai","sequence":"first","affiliation":[{"name":"Unit of Pathology, Department of Biomedical, Biotechnological and Translational Sciences (S.Bi.Bi.T.), Parma, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Letizia","family":"Gnetti","sequence":"additional","affiliation":[{"name":"Unit of Pathology, Department of Biomedical, Biotechnological and Translational Sciences (S.Bi.Bi.T.), Parma, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annalisa","family":"Gilli","sequence":"additional","affiliation":[{"name":"Medical Oncology Unit, Department of Emergency and General and Specialistic Medical Area, University Hospital of Parma, Parma, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pietro","family":"Caruana","sequence":"additional","affiliation":[{"name":"Unit of Pathology, Department of Biomedical, Biotechnological and Translational Sciences (S.Bi.Bi.T.), Parma, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raffaele Dalla","family":"Valle","sequence":"additional","affiliation":[{"name":"Clinical and Transplantation Surgery, Department of General and Specialistic Surgery, University Hospital of Parma, Parma, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastiano","family":"Buti","sequence":"additional","affiliation":[{"name":"Medical Oncology Unit, Department of Emergency 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