{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:41:43Z","timestamp":1786650103106,"version":"build-2736575974"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2015,10]]},"abstract":"<jats:p>Large lymphoid proliferations are usually regarded as synonymous with lymphomas. However, lymphoma-like lesions. (LLLs) of the cervix are amongst the exception. We report a 46-year-old woman who complained of irregular menses and was found to have superficial erosion in cervix, which on biopsy showed clusters of large atypical appearing lymphoid cells admixed with smaller reactive lymphoid cells. On immunohistochemistry, these large cells were strongly positive for CD20 and CD30 and the background cells were reactive to CD3. Based on the superficial nature of infiltrate and absence of a mass-forming lesion, a diagnosis of LLL of cervix was made. Despite a benign diagnosis, a hysterectomy was done on patient's insistence and only a focus of lymphoid cells similar to biopsy was seen on the operated specimen. Patient is free of disease on follow-up.<\/jats:p>","DOI":"10.4103\/0973-1482.155979","type":"journal-article","created":{"date-parts":[[2016,2,19]],"date-time":"2016-02-19T00:48:49Z","timestamp":1455842929000},"page":"1035-1035","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Florid reactive lymphoid hyperplasia (lymphoma-like lesion) of cervix: A diagnostically challenging case and a brief review of literature"],"prefix":"10.4103","volume":"11","author":[{"given":"Trupti","family":"Pai","sequence":"first","affiliation":[{"name":"Department of Pathology, Tata Memorial Hospital, Parel, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santosh","family":"Menon","sequence":"additional","affiliation":[{"name":"Department of Pathology, Tata Memorial Hospital, Parel, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kedar","family":"Deodhar","sequence":"additional","affiliation":[{"name":"Department of Pathology, Tata Memorial Hospital, Parel, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanuja","family":"Shet","sequence":"additional","affiliation":[{"name":"Department of Pathology, Tata Memorial Hospital, Parel, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2016,2,15]]},"reference":[{"key":"R1-20260109","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1097\/00004347-198512000-00002","article-title":"Lymphoma-like lesions of the lower female genital tract: A report of 16 cases","volume":"4","author":"Young","year":"1985","journal-title":"Int J Gynaec Pathol"},{"key":"R2-20260109","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1097\/01.pgp.0000228144.59677.5a","article-title":"Lymphoma-like lesion of the uterine cervix: Report of 12 cases of a rare entity","volume":"26","author":"Ma","year":"2007","journal-title":"Int J Gynecol Pathol"},{"key":"R3-20260109","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1002\/ajh.10334","article-title":"Primary B-cell lymphoma and lymphoma-like lesions of the uterine cervix","volume":"73","author":"Au","year":"2003","journal-title":"Am J Hematol"},{"key":"R4-20260109","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/S0301-2115(00)00513-3","article-title":"Lymphoma-like lesion of the uterine cervix","volume":"97","author":"Piura","year":"2001","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"R5-20260109","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1097\/PAS.0b013e3181cc4f12","article-title":"Florid reactive lymphoid hyperplasia of the lower female genital tract (lymphoma-like lesion): A benign condition that frequently harbors clonal immunoglobulin heavy chain gene rearrangements","volume":"34","author":"Geyer","year":"2010","journal-title":"Am J Surg Pathol"},{"key":"R6-20260109","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1111\/j.1365-2141.2011.08659.x","article-title":"Primary lymphoma-like lesions of the uterine cervix; 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