{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:40:13Z","timestamp":1786650013952,"version":"build-2736575974"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>The objective of this study is to investigate the risk factors for developing postthymectomy myasthenic crisis in thymoma patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods:<\/jats:title>\n                    <jats:p>\n                      Patients with thymoma received thymectomy from January 2001 to December 2014 were reviewed and included in this retrospective study in Lishui People's Hospital. Seventy-seven patients were included in this study. For the 77 cases, 66 patients not developing postthymectomy myasthenic crisis were considered as a control group, and other 11 subjects developing postthymectomy myasthenic were considered as the case group. The potential risk factors such age, gender, Osseman stage, Masaoka, pyridostigmine bromide, and\n                      <jats:italic toggle=\"yes\">et al<\/jats:italic>\n                      . were compared between case and control group firstly by Chi-square test or Student's\n                      <jats:italic toggle=\"yes\">t<\/jats:italic>\n                      -test and then by logistic regression test.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Eleven patients developed postthymectomy myasthenic with the incidence of 14.3%; logistic regression analysis indicates that pyridostigmine bromide &gt;360 mg\/day administration (OR = 21.2,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05), postsurgery pulmonary infection (OR = 8.3,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05) and myasthenic crisis prior surgery (OR = 3.2,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05) were the independent risk factors for developing postthymectomy myasthenic crisis in thymoma patients.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Thymoma patients with a large dosage of pyridostigmine bromide administration, postsurgery pulmonary infection and myasthenic crisis prior surgery were easy to have postthymectomy myasthenic crisis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/0973-1482.163863","type":"journal-article","created":{"date-parts":[[2015,8,31]],"date-time":"2015-08-31T23:57:49Z","timestamp":1441065469000},"page":"S115-S117","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":6,"title":["Risk factors for developing postthymectomy myasthenic crisis in thymoma Patients"],"prefix":"10.4103","volume":"11","author":[{"given":"Yueming","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Intensive Care Unit, The People\u2032s Hospital of Lishui, Lishui 323000, PR China"},{"name":"Department of Emergency, The People\u2032s Hospital of Lishui, Lishui 323000, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yipeng","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Unit, The People\u2032s Hospital of Lishui, Lishui 323000, PR 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