{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:28:14Z","timestamp":1786649294110,"version":"build-2736575974"},"reference-count":15,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:sec>\n                    <jats:title>Aim of the Study:<\/jats:title>\n                    <jats:p>The aim of this study was to correlate the clinical staging (clinical severity) with the histopathological staging (histopathological changes) of oral submucous fibrosis (OSF) patients, which would further assist the clinicians to formulate a definite treatment plan.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>The study group consisted of 50 subjects who were clinically and histologically diagnosed as OSF. Detailed information was gathered in a pretested proforma with emphasis on the various addictions. The clinical findings were noted; punch biopsy was performed followed by histological examination. Clinical and histological staging were divided into four stages, as Stages I\u2013IV according to Khanna and Andrade classification.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The 50 subjects were in the age range of 18\u201370 years, of which 20 patients were in clinical Group III, 15 were in histopathological stage III, 2, 1, and 2 in Stage II, Stage I, and Stage IV, respectively, out of 5 patients in clinical Group IV, 4 were in histopathological staging IV and 1 was in Stage III, out of 5 patients in clinical Group I, 3 and 2 were in histologic Stages II and I, respectively. Statistical analysis with Chi-square test showed high significance with\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The correlation of clinical and histopathological staging was found to be highly significant, thus suggesting that the subject with clinically advanced OSF had extensive fibrosis histologically.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/0973-1482.176177","type":"journal-article","created":{"date-parts":[[2018,6,12]],"date-time":"2018-06-12T08:26:37Z","timestamp":1528791997000},"page":"597-603","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":10,"title":["Oral submucous fibrosis: A clinico-histopathological correlational study"],"prefix":"10.4103","volume":"14","author":[{"given":"Sudharani Basawaraj","family":"Biradar","sequence":"first","affiliation":[{"name":"Department of Oral Medicine and Radiology, Rural Dental College, Pravara Institute of Medical Sciences, Ahmednagar, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anita Dnyanoba","family":"Munde","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, Rural Dental College, Pravara Institute of Medical Sciences, Ahmednagar, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Basawaraj Chanabasappa","family":"Biradar","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Rural Dental College, Pravara Institute of Medical Sciences, Ahmednagar, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Safia Shoeb","family":"Shaik","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, Rural Dental College, Pravara Institute of Medical Sciences, Ahmednagar, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shweta","family":"Mishra","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, Shri Ramachandra Bhanj Dental College and Hospital, Cuttack, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2018,6,12]]},"reference":[{"key":"R1-20260109","doi-asserted-by":"crossref","first-page":"133","DOI":"10.5005\/jp-journals-10011-1031","article-title":"Correlation between clinical and histological staging of oral submucous fibrosis","volume":"22","author":"Shivakumar","year":"2010","journal-title":"J Indian Acad Oral Med Radiol"},{"key":"R2-20260109","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1016\/0030-4220(66)90367-7","article-title":"Oral submucous fibrosis","volume":"22","author":"Pindborg","year":"1966","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"R3-20260109","first-page":"21","article-title":"Oral submucous fibrosis: Correlation of clinical grading to various habit factors","volume":"3","author":"Reddy","year":"2011","journal-title":"Int J Dent Clin"},{"key":"R4-20260109","doi-asserted-by":"crossref","first-page":"106","DOI":"10.4103\/0970-9290.33785","article-title":"Oral submucous fibrosis: A clinico-histopathological study in Chennai","volume":"18","author":"Kiran Kumar","year":"2007","journal-title":"Indian J Dent Res"},{"key":"R5-20260109","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/S0901-5027(05)80473-4","article-title":"Oral submucous fibrosis: A new concept in surgical management. 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