{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T17:28:47Z","timestamp":1786728527930,"version":"build-2736575974"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:p>Interdigitating dendritic cell tumor\/sarcoma (IDCT) is a very rare and aggressive neoplasm arising from antigen-presenting cells. It usually involves lymph nodes, but extranodal sites can also be involved. Because of the rarity of the disease, consistent standard treatment guidelines have not been established till date. We report a case of a 35-year-old female who presented with right-sided neck swelling and anterior mediastinal mass. Histopathology revealed large mononucleated cells with background of mixed polymorphous inflammatory cells suspicious of Hodgkin's lymphoma. Hence, to confirm the diagnosis, immunohistochemistry was done. Immunohistochemistry revealed that the tumor was CD30 \u2013 negative, CD10 \u2013 negative, CD2 \u2013 negative, leukocyte common antigen \u2013 positive, vimentin \u2013 positive, and S-100 \u2013 positive, diagnostic of IDCT. Patient was treated with eight cycles of cyclophosphamide, doxorubicin, vincristine, and prednisolone regimen chemotherapy followed by involved field radiotherapy and showed dramatic response with complete resolution of mediastinal mass.<\/jats:p>","DOI":"10.4103\/0973-1482.183189","type":"journal-article","created":{"date-parts":[[2017,2,8]],"date-time":"2017-02-08T02:08:56Z","timestamp":1486519736000},"page":"690-693","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":6,"title":["Interdigitating dendritic cell tumor: A rare case report with review of literature"],"prefix":"10.4103","volume":"14","author":[{"given":"Irappa","family":"Madabhavi","sequence":"first","affiliation":[{"name":"Department of Medical and Pediatric Oncology, GCRI, Ahmedabad, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Apurva","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Medical and Pediatric Oncology, GCRI, Ahmedabad, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaurang","family":"Modi","sequence":"additional","affiliation":[{"name":"Department of Medical and Pediatric Oncology, GCRI, Ahmedabad, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asha","family":"Anand","sequence":"additional","affiliation":[{"name":"Department of Medical and Pediatric Oncology, GCRI, Ahmedabad, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harsha","family":"Panchal","sequence":"additional","affiliation":[{"name":"Department of Medical and Pediatric Oncology, GCRI, Ahmedabad, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonia","family":"Parikh","sequence":"additional","affiliation":[{"name":"Department of Medical and Pediatric Oncology, GCRI, Ahmedabad, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2018,6,12]]},"reference":[{"key":"R1-20260109","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1002\/(SICI)1096-8652(199810)59:2<161::AID-AJH10>3.0.CO;2-C","article-title":"Follicular dendritic cell sarcoma and interdigitating reticulum cell sarcoma: A review","volume":"59","author":"Fonseca","year":"1998","journal-title":"Am J Hematol"},{"key":"R2-20260109","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1002\/ajh.20857","article-title":"Dendritic cell neoplasms: An overview","volume":"82","author":"Kairouz","year":"2007","journal-title":"Am J Hematol"},{"key":"R3-20260109","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.critrevonc.2007.06.003","article-title":"Dendritic cell sarcoma: An analytic overview of the literature and presentation of original five cases","volume":"65","author":"De Pas","year":"2008","journal-title":"Crit Rev Oncol Hematol"},{"key":"R4-20260109","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.critrevonc.2013.05.006","article-title":"Dendritic cell sarcoma: A pooled analysis including 462 cases with presentation of our case series","volume":"88","author":"Saygin","year":"2013","journal-title":"Crit Rev Oncol Hematol"},{"key":"R5-20260109","doi-asserted-by":"crossref","first-page":"304","DOI":"10.3346\/jkms.2011.26.2.304","article-title":"Extranodal interdigitating dendritic cell sarcoma presenting in the pleura: A case report","volume":"26","author":"Han","year":"2011","journal-title":"J Korean Med Sci"},{"key":"R6-20260109","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1002\/dc.10280","article-title":"Interdigitating dendritic reticulum cell tumor of lymph nodes: Case report with differential diagnostic considerations","volume":"28","author":"Ylagan","year":"2003","journal-title":"Diagn Cytopathol"},{"key":"R7-20260109","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/j.prp.2012.02.004","article-title":"Interdigitating dendritic cell sarcoma presenting in the nasal region","volume":"208","author":"Parada","year":"2012","journal-title":"Pathol Res Pract"},{"key":"R8-20260109","doi-asserted-by":"crossref","first-page":"150","DOI":"10.5045\/kjh.2012.47.2.150","article-title":"Successful treatment of disseminated interdigitating dendritic cell sarcoma with adriamycin, bleomycin, vinblastine, and dacarbazine chemotherapy","volume":"47","author":"Lee","year":"2012","journal-title":"Korean J Hematol"},{"key":"R9-20260109","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1309\/M95G-7DQ2-TLQL-7Q11","article-title":"Interdigitating dendritic cell sarcoma. 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