{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:36:23Z","timestamp":1786649783415,"version":"build-2736575974"},"reference-count":7,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2017,10]]},"abstract":"<jats:p>Adenoid cystic carcinoma (ACC) is a rare neoplasm and the most frequent pathology occurring in the minor salivary glands. Lung, bone, liver, and brain are the most frequent metastasis sites in ACC cases. To our knowledge, cecal and ileum metastasis from ACC has not been previously reported in literature. Herein, we reported a case of cecal and small bowel metastasis (ileum) in a patient with ACC. A 41-year-old male patient with ACC developed iron and Vitamin B12 deficiency anemia during further controls. Lower gastrointestinal (GI) endoscopy detected an ulcerated polypoid lesion with raised margins in cecum. Pathological evaluation of polyp biopsy was consistent with metastasis from ACC. The patient underwent surgery of right hemicolectomy. Pathological examinations revealed an ACC of cecum and small bowel (ileum) showing positive staining with CD117, CK7, and panCK. We aimed to emphasize that performing GI stromal screening in ACC patients presenting with iron deficiency is important for early diagnosis of metastasis.<\/jats:p>","DOI":"10.4103\/0973-1482.183549","type":"journal-article","created":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T13:01:10Z","timestamp":1767790870000},"page":"1070-1072","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Small bowel and cecal Involvement: Unusual metastasis sites from adenoid cystic carcinoma of the minor salivary gland"],"prefix":"10.4103","volume":"13","author":[{"given":"Yakup","family":"Bozkaya","sequence":"first","affiliation":[{"name":"Department of Medical Oncology, Ankara Numune Training and Research Hospital, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erdin\u00e7","family":"\u00c7etinkaya","sequence":"additional","affiliation":[{"name":"Department of Surgery, Ankara Numune Training and Research Hospital, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gokmen Umut","family":"Erdem","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Ankara Numune Training and Research Hospital, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ay\u015fe Yylmaz","family":"\u00c7ift\u00e7i","sequence":"additional","affiliation":[{"name":"Department of Pathology, Ankara Numune Training and Research Hospital, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ercan Aydyn","family":"Karahalilo\u011flu","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Ankara Numune Training and Research Hospital, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuriye","family":"\u00d6zdemir","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Faculty of Medicine, Y\u0131ld\u0131r\u0131m Beyaz\u0131t University, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20260109","doi-asserted-by":"crossref","first-page":"pii:Bcr0120125658","DOI":"10.1136\/bcr-01-2012-5658","article-title":"Adenoid cystic carcinoma of hard palate with coincidental metastases to lung and liver","volume":"2013","author":"Akhavan","year":"2013","journal-title":"BMJ Case Rep"},{"key":"R2-20260109","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/j.ajoms.2013.09.013","article-title":"Distant metastasis and survival of adenoid cystic carcinoma after definitive treatment","volume":"26","author":"Shingaki","year":"2014","journal-title":"J Oral Maxillofac Surg Med Pathol"},{"key":"R3-20260109","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.1288\/00005537-198410000-00011","article-title":"Adenoid cystic carcinoma of major and minor salivary gland origin","volume":"94","author":"Matsuba","year":"1984","journal-title":"Laryngoscope"},{"key":"R4-20260109","first-page":"XD09","article-title":"Extradural spinal metastasis of adenoid cystic carcinoma (ACC): A case report","volume":"9","author":"Kumar","year":"2015","journal-title":"J Clin Diagn Res"},{"key":"R5-20260109","first-page":"69","article-title":"Lung metastasis from TTF-1 positive sigmoid adenocarcinoma. Pitfalls and management","volume":"105","author":"Remo","year":"2013","journal-title":"Pathologica"},{"key":"R6-20260109","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1016\/j.oraloncology.2015.04.005","article-title":"Adenoid cystic carcinoma of the head and neck \u2013 An update","volume":"51","author":"Coca-Pelaz","year":"2015","journal-title":"Oral Oncol"},{"key":"R7-20260109","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1590\/S1516-31802006000100006","article-title":"Management of salivary gland adenoid cystic carcinoma: Institutional experience of a case series","volume":"124","author":"Tincani","year":"2006","journal-title":"Sao Paulo Med J"}],"container-title":["Journal of Cancer Research and Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/01363817-201713060-00035","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T18:58:22Z","timestamp":1786647502000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/01363817-201713060-00035"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10]]},"references-count":7,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2017]]}},"URL":"https:\/\/doi.org\/10.4103\/0973-1482.183549","relation":{},"ISSN":["0973-1482","1998-4138"],"issn-type":[{"value":"0973-1482","type":"print"},{"value":"1998-4138","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,10]]}}}