{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:42:44Z","timestamp":1787071364088,"version":"build-2736575974"},"reference-count":21,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2015,7]]},"abstract":"<jats:p>\n                    Deep venous thrombosis (DVT) has been reported extensively following ovarian hyperstimulation syndrome during\n                    <jats:italic toggle=\"yes\">in-vitro<\/jats:italic>\n                    fertilization (IVF). Pregnancy\n                    <jats:italic toggle=\"yes\">per se<\/jats:italic>\n                    increases the risk of DVT due to a hypercoagulable state. The long-term use of hormone replacement therapy (HRT) is another critical factor associated with DVT in women. However, an association between the short-term use of HRT in oocyte donation (OD) cycles and DVT has not yet been reported. We present a case of 43-year-old woman who developed DVT after IVF-OD. DVT was diagnosed at 7 weeks of pregnancy and was managed with low-molecular-weight heparin. We suggest that even a short-term use of HRT should be considered a risk factor for DVT especially in the presence of additional risk factors such as obesity. The patient had an uneventful recovery and delivered three healthy though preterm babies.\n                  <\/jats:p>","DOI":"10.4103\/0974-1208.165150","type":"journal-article","created":{"date-parts":[[2015,9,11]],"date-time":"2015-09-11T07:01:55Z","timestamp":1441954915000},"page":"182-185","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Deep venous thrombosis in a patient undergoing In-vitro fertilization with oocyte donation"],"prefix":"10.4103","volume":"8","author":[{"given":"Nalini","family":"Mahajan","sequence":"first","affiliation":[{"name":"Nova IVI Fertility, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Padmaja","family":"Naidu","sequence":"additional","affiliation":[{"name":"Nova IVI Fertility, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shalu","family":"Gupta","sequence":"additional","affiliation":[{"name":"Nova IVI Fertility, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kumkum","family":"Rani","sequence":"additional","affiliation":[{"name":"Nova IVI Fertility, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20250922","first-page":"187","article-title":"Thrombosis, thrombophilia, and thromboprophylaxis in pregnancy","volume":"3","author":"James","year":"2005","journal-title":"Clin Adv Hematol Oncol"},{"key":"R2-20250922","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1093\/humrep\/det458","article-title":"Increased venous thrombosis incidence in pregnancies after in vitro fertilization","volume":"29","author":"Hansen","year":"2014","journal-title":"Hum Reprod"},{"key":"R3-20250922","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1111\/j.1538-7836.2006.02026.x","article-title":"A review of upper extremity deep vein thrombosis in pregnancy: Unmasking the \u2018ART\u2019 behind the clot","volume":"4","author":"Chan","year":"2006","journal-title":"J Thromb Haemost"},{"key":"R4-20250922","doi-asserted-by":"crossref","first-page":"1661","DOI":"10.1111\/j.1538-7836.2006.02062.x","article-title":"Artificial reproductive technology and the risk of venous thromboembolic disease","volume":"4","author":"Nelson","year":"2006","journal-title":"J Thromb Haemost"},{"key":"R5-20250922","doi-asserted-by":"crossref","first-page":"e003208","DOI":"10.1136\/bmjopen-2013-003208","article-title":"Risk marker associations with venous thrombotic events: A cross-sectional analysis","volume":"4","author":"Golomb","year":"2014","journal-title":"BMJ Open"},{"issue":"Suppl 1","key":"R6-20250922","doi-asserted-by":"crossref","first-page":"S4","DOI":"10.1016\/S0049-3848(13)70009-4","article-title":"Mechanisms of hormonal therapy related thrombosis","volume":"131","author":"Sandset","year":"2013","journal-title":"Thromb Res"},{"key":"R7-20250922","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1111\/j.1538-7836.2008.02961.x","article-title":"Ante- and postnatal risk factors of venous thrombosis: A hospital-based case-control study","volume":"6","author":"Jacobsen","year":"2008","journal-title":"J Thromb Haemost"},{"key":"R8-20250922","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.beha.2012.07.006","article-title":"Venous thromboembolism associated with pregnancy and hormonal therapy","volume":"25","author":"Jacobsen","year":"2012","journal-title":"Best Pract Res Clin Haematol"},{"key":"R9-20250922","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1053\/j.seminhematol.2007.02.004","article-title":"Epidemiology and risk factors for venous thrombosis","volume":"44","author":"Cushman","year":"2007","journal-title":"Semin Hematol"},{"key":"R10-20250922","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S1521-6926(03)00021-5","article-title":"Haemostatic changes in pregnancy","volume":"16","author":"Bremme","year":"2003","journal-title":"Best Pract Res Clin Haematol"},{"key":"R11-20250922","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/S0049-3848(98)00028-0","article-title":"Oral contraception and factor V Leiden mutation in relation to localization of deep vein thrombosis","volume":"90","author":"Andersen","year":"1998","journal-title":"Thromb Res"},{"key":"R12-20250922","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1055\/s-2006-942222","article-title":"Thromboembolic diseases in pregnancy","volume":"211","author":"Richter","year":"2007","journal-title":"Z Geburtshilfe Neonatol"},{"key":"R13-20250922","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.fertnstert.2011.10.038","article-title":"Venous thromboembolism in relation to in vitro fertilization: An approach to determining the incidence and increase in risk in successful cycles","volume":"97","author":"Rova","year":"2012","journal-title":"Fertil Steril"},{"key":"R14-20250922","doi-asserted-by":"crossref","first-page":"e8632","DOI":"10.1136\/bmj.e8632","article-title":"Incidence of pulmonary and venous thromboembolism in pregnancies after in vitro fertilisation: Cross sectional study","volume":"346","author":"Henriksson","year":"2013","journal-title":"BMJ"},{"key":"R15-20250922","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1093\/humrep\/des041","article-title":"No evidence that assisted reproduction increases the risk of thrombosis: A Danish national cohort study","volume":"27","author":"Hansen","year":"2012","journal-title":"Hum Reprod"},{"key":"R16-20250922","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1111\/j.1538-7836.2005.01268.x","article-title":"Does the type of hormone replacement therapy influence the risk of deep vein thrombosis?. A prospective case-control study","volume":"3","author":"Douketis","year":"2005","journal-title":"J Thromb Haemost"},{"key":"R17-20250922","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.bpobgyn.2014.08.012","article-title":"Deep venous thrombosis and pulmonary embolism in obese women","volume":"29","author":"Drife","year":"2015","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"key":"R18-20250922","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.3109\/14767058.2014.944155","article-title":"Can we identify risk factors during pregnancy for thrombo-embolic events during the puerperium and later in life?","volume":"28","author":"Waldman","year":"2015","journal-title":"J Matern Fetal Neonatal Med"},{"key":"R19-20250922","article-title":"Obesity as a causal risk factor for deep venous thrombosis: A Mendelian randomization study","author":"Klovaite","year":"2014","journal-title":"Journal of internal medicine"},{"key":"R20-20250922","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1046\/j.1538-7836.2003.00031.x","article-title":"The epidemiology of venous thromboembolism in Caucasians and African-Americans: The GATE Study","volume":"1","author":"Dowling","year":"2003","journal-title":"J Thromb Haemost"},{"key":"R21-20250922","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1055\/s-0037-1613828","article-title":"Minor events and the risk of deep venous thrombosis","volume":"83","author":"Eekhoff","year":"2000","journal-title":"Thromb Haemost"}],"container-title":["Journal of Human Reproductive Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/01363858-201508030-00013","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:44:57Z","timestamp":1787067897000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/01363858-201508030-00013"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,7]]},"references-count":21,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015]]}},"URL":"https:\/\/doi.org\/10.4103\/0974-1208.165150","relation":{},"ISSN":["0974-1208","1998-4766"],"issn-type":[{"value":"0974-1208","type":"print"},{"value":"1998-4766","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,7]]},"assertion":[{"value":"2015-04-16","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-07-10","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}