{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T20:03:22Z","timestamp":1787169802393,"version":"build-2736575974"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:sec>\n                    <jats:title>Study Question:<\/jats:title>\n                    <jats:p>What are the good practice guidelines for Pre implantation genetic testing applicable in INDIA?<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>What is Already Known:<\/jats:title>\n                    <jats:p>Pre-Implantation Genetic Testing (PGT) is not new in India. It is used to identify euploid embryos for transfer, thus enabling couples to achieve a healthy pregnancy. There has been a lot of controversy surrounding PGT in the international forums; most of these debates have failed to reach a consensus on whether PGT should be offered or its concerns be validated more.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design, Size, Duration:<\/jats:title>\n                    <jats:p>This is the report of a 2-day consensus meeting where two moderators were assigned to a group of experts to collate information on Pre implantation genetic testing and embryo biopsy practices in INDIA. This meeting utilised surveys, available scientific evidence and personal laboratory experience into various presentations by experts on pre-decided specific topics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants\/Materials, Setting, Methods:<\/jats:title>\n                    <jats:p>Expert professionals from ISAR representing clinical, embryological and genetic fields.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Results and the Role of Chance:<\/jats:title>\n                    <jats:p>The report is divided into various components defining the terminologies, the various requirements, qualifications, recommendations on PGT -A,M,SR, and quality management: the report and recommendations of the expert panel reflect the discussion on each of the topics and try to lay down good practice points for labs to follow.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Limitations, Reasons for Caution:<\/jats:title>\n                    <jats:p>The recommendations are solely based on expert opinion. Future availability of data may warrant an update of the same.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Wider Implications of the Findings:<\/jats:title>\n                    <jats:p>These guidelines can help labs across the country to standardise their PGT services and improve clinical outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Funding\/Competing Interest(S):<\/jats:title>\n                    <jats:p>The consensus meeting and writing of the paper was supported by funds from CooperSurgical India.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/0974-1208.330503","type":"journal-article","created":{"date-parts":[[2021,11,15]],"date-time":"2021-11-15T08:39:08Z","timestamp":1636965548000},"page":"S31-S47","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["Indian Society for Assisted Reproduction Consensus Guidelines on Preimplantation Genetic Testing in In vitro Fertilization Clinics"],"prefix":"10.4103","volume":"14","author":[{"given":"Jaideep","family":"Malhotra","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keshav","family":"Malhotra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaurav","family":"Majumdar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ritu","family":"Hari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijayakumar","family":"Chelur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sayali","family":"Kandari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dayanidhi","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nishad","family":"Chimote","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manjeet S","family":"Mehta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarabpreet","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feseena","family":"Sethi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijay S","family":"Mangoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parasuram","family":"Gopinath","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krishna","family":"Chaitanya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priya","family":"Selvaraj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R2-3-20240905","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1093\/humrep\/dep450","article-title":"Accreditation of the PGD laboratory","volume":"25","author":"Harper","year":"2010","journal-title":"Hum Reprod"},{"key":"R3-3-20240905","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1007\/s40556-018-0159-1","article-title":"Preimplantation genetic diagnosis in India: The current scenario and potential developments","volume":"5","author":"Kar","year":"2018","journal-title":"J Fetal Med"},{"key":"R7-3-20240905","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1007\/s10815-009-9369-8","article-title":"Vitrification of human embryos subjected to blastomere biopsy for pre-implantation genetic screening produces higher survival and pregnancy rates than slow freezing","volume":"26","author":"Keskintepe","year":"2009","journal-title":"J Assist Reprod Genet"},{"key":"R9-3-20240905","doi-asserted-by":"crossref","first-page":"306","DOI":"10.4103\/jhrs.JHRS_132_18","article-title":"Preimplantation genetic testing: Its evolution, where are we today?","volume":"11","author":"Parikh","year":"2018","journal-title":"J Hum Reprod Sci"},{"key":"R10-3-20240905","doi-asserted-by":"crossref","first-page":"1414","DOI":"10.1016\/j.fertnstert.2016.08.017","article-title":"Why do euploid embryos miscarry. 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