{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T19:48:24Z","timestamp":1793994504550,"version":"4.8.0"},"reference-count":17,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Emerg Trauma Shock"],"published-print":{"date-parts":[[2016]]},"DOI":"10.4103\/0974-2700.173868","type":"journal-article","created":{"date-parts":[[2016,1,13]],"date-time":"2016-01-13T19:46:16Z","timestamp":1452714376000},"page":"22","source":"Crossref","is-referenced-by-count":83,"title":["Early surgical intervention and its impact on patients presenting with necrotizing soft tissue infections: A single academic center experience"],"prefix":"10.4103","volume":"9","author":[{"given":"Rifat","family":"Latifi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"GeorgeJ","family":"Hadeed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Terrence","family":"O'Keeffe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Narong","family":"Kulvatunyou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JulieL","family":"Wynne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bellal","family":"Joseph","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"RandallS","family":"Friese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ThomasL","family":"Wachtel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"PeterM","family":"Rhee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayman","family":"El-Menyar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"key-10.4103\/0974-2700.173868-1","first-page":"7","volume-title":"Necrotizing soft tissue infections: obstacles in diagnosis","author":"Lille","year":"1996","journal-title":"J Am Coll Surg"},{"key":"key-10.4103\/0974-2700.173868-2","first-page":"139","volume-title":"Community-acquired necrotizing soft tissue infections: a review of 122 cases presenting to a single emergency department over 12 years","author":"Frazee","year":"2008","journal-title":"J Emerg Med"},{"key":"key-10.4103\/0974-2700.173868-3","first-page":"841","volume-title":"Necrotizing soft tissue infections: improved outcomes with modern care","author":"Tillou","year":"2004","journal-title":"Am Surg"},{"key":"key-10.4103\/0974-2700.173868-4","first-page":"488","volume-title":"Necrotizing fasciitis: 10 years' experience in a district general hospital","author":"Ward","year":"1991","journal-title":"Br J Surg"},{"key":"key-10.4103\/0974-2700.173868-5","first-page":"558","volume-title":"Determinants of mortality for necrotizing soft-tissue infections","author":"McHenry","year":"1995","journal-title":"Ann Surg"},{"key":"key-10.4103\/0974-2700.173868-6","first-page":"397","volume-title":"Aggressive surgical management of necrotizing fasciitis serves to decrease mortality: a retrospective study","author":"Bilton","year":"1998","journal-title":"Am Surg"},{"key":"key-10.4103\/0974-2700.173868-7","first-page":"847","volume-title":"Influence of surgical treatment timing on mortality from necrotizing soft tissue infections requiring intensive care management","author":"Boyer","year":"2009","journal-title":"Intensive Care Med"},{"key":"key-10.4103\/0974-2700.173868-8","first-page":"443","volume-title":"Outcome of necrotizing skin and soft tissue infections","author":"Gunter","year":"2008","journal-title":"Surg Infect (Larchmt)"},{"key":"key-10.4103\/0974-2700.173868-9","first-page":"580","volume-title":"Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012","author":"Dellinger","year":"2013","journal-title":"Crit Care Med"},{"key":"key-10.4103\/0974-2700.173868-10","doi-asserted-by":"crossref","unstructured":"Al-Thani H, El-Menyar A, Shaikh N, Mudali IN, Mekkodathil A, et al. Risk stratification of necrotizing fasciitis based on the initial procalcitonin concentration: A single center observational study. Surg Infect (Larchmt) 2015. PMID:26280767. [Epub ahead of print].","DOI":"10.1089\/sur.2014.249"},{"key":"key-10.4103\/0974-2700.173868-11","first-page":"419","volume-title":"Immunocompromised status in patients with necrotizing soft-tissue infection","author":"Keung","year":"2013","journal-title":"JAMA Surg"},{"key":"key-10.4103\/0974-2700.173868-12","first-page":"227","volume-title":"A simple model to help distinguish necrotizing fasciitis from nonnecrotizing soft tissue infection","author":"Wall","year":"2000","journal-title":"J Am Coll Surg"},{"key":"key-10.4103\/0974-2700.173868-13","first-page":"151","volume-title":"Predictors of mortality and limb loss in necrotizing soft tissue infections","author":"Anaya","year":"2005","journal-title":"Arch Surg"},{"key":"key-10.4103\/0974-2700.173868-14","first-page":"1535","volume-title":"The LRINEC (Laboratory Risk Indicator for Necrotizing Fasciitis) score: a tool for distinguishing necrotizing fasciitis from other soft tissue infections","author":"Wong","year":"2004","journal-title":"Crit Care Med"},{"key":"key-10.4103\/0974-2700.173868-15","first-page":"57","volume-title":"A five-year review of necrotising fasciitis in a tertiary referral unit","author":"Swain","year":"2013","journal-title":"Ann R Coll Surg Engl"},{"key":"key-10.4103\/0974-2700.173868-16","first-page":"21","volume-title":"Hyperbaric oxygen does not improve outcome in patients with necrotizing soft tissue infection","author":"George","year":"2009","journal-title":"Surg Infect (Larchmt)"},{"key":"key-10.4103\/0974-2700.173868-17","first-page":"1400","volume-title":"Necrotizing soft tissue infections: delayed surgical treatment is associated with increased number of surgical debridements and morbidity","author":"Kobayashi","year":"2011","journal-title":"J Trauma"}],"container-title":["Journal of Emergencies, Trauma, and Shock"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:30:23Z","timestamp":1786649423000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/0974-2700.173868"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":17,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016]]}},"alternative-id":["173868"],"URL":"https:\/\/doi.org\/10.4103\/0974-2700.173868","relation":{},"ISSN":["0974-2700"],"issn-type":[{"value":"0974-2700","type":"print"}],"subject":[],"published":{"date-parts":[[2016]]}}}