{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T05:29:04Z","timestamp":1787030944618,"version":"build-2736575974"},"reference-count":8,"publisher":"Scientific Scholar","issue":"02","license":[{"start":{"date-parts":[[2020,4,19]],"date-time":"2020-04-19T00:00:00Z","timestamp":1587254400000},"content-version":"vor","delay-in-days":1388,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Lab Physicians"],"published-print":{"date-parts":[[2016,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Histoplasma capsulatum is no longer confined to certain geographic areas and should always be considered in the differential diagnosis of lymphadenopathy and organomegaly in HIV-positive patients. We present an unusual case of a 20-year-old immunocompromised male of African origin presenting with fever, jaundice, hepatosplenomegaly, and retroperitoneal and cervical lymphadenopathy. Fine needle aspiration (FNA) smears from the cervical lymph node revealed numerous yeast forms of histoplasma in macrophages. The patient succumbed to the fulminant infection. Postmortem liver biopsy also revealed infiltration by histoplasma, confirming the diagnosis of disseminated histoplasmosis. This case highlights the variable nature of the clinical presentation of disseminated histoplasmosis which can mimic tuberculosis, leishmaniasis, or lymphoma. FNA cytology is a rapid, cost-effective, and reliable diagnostic tool for early detection and prompt management of histoplasmosis.<\/jats:p>","DOI":"10.4103\/0974-2727.180797","type":"journal-article","created":{"date-parts":[[2016,4,21]],"date-time":"2016-04-21T02:55:39Z","timestamp":1461207339000},"page":"129-131","source":"Crossref","is-referenced-by-count":2,"title":["Disseminated Histoplasmosis: A Fatal Opportunistic Infection in Disguise"],"prefix":"10.25259","volume":"8","author":[{"given":"Ruchita","family":"Tyagi","sequence":"additional","affiliation":[{"name":"Department of Pathology, Dayanand Medical College and Hospital, Ludhiana, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arshdeep","family":"Kaur","sequence":"additional","affiliation":[{"name":"Department of Pathology, Dayanand Medical College and Hospital, Ludhiana, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pavneet Kaur","family":"Selhi","sequence":"additional","affiliation":[{"name":"Department of Pathology, Dayanand Medical College and Hospital, Ludhiana, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harpreet Kaur","family":"Puri","sequence":"additional","affiliation":[{"name":"Department of Pathology, Dayanand Medical College and Hospital, Ludhiana, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neena","family":"Sood","sequence":"additional","affiliation":[{"name":"Department of Pathology, Dayanand Medical College and Hospital, Ludhiana, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2020,4,19]]},"reference":[{"key":"key-10.4103\/0974-2727.180797-1","first-page":"982","volume-title":"Histoplasma capsulatum: More widespread than previously thought","author":"Antinori","year":"2014","journal-title":"Am J Trop Med Hyg"},{"key":"key-10.4103\/0974-2727.180797-2","first-page":"115","volume-title":"Histoplasmosis: A clinical and laboratory update","author":"Kauffman","year":"2007","journal-title":"Clin Microbiol Rev"},{"key":"key-10.4103\/0974-2727.180797-3","first-page":"1199","volume-title":"Disseminated histoplasmosis in patients with AIDS in Panama: A review of 104 cases","author":"Gutierrez","year":"2005","journal-title":"Clin Infect Dis"},{"key":"key-10.4103\/0974-2727.180797-4","first-page":"23","volume-title":"Acute Disseminated Histoplasmosisin a patient with AIDS","author":"Singh","year":"1996","journal-title":"Indian J Med Microbiol","ISSN":"https:\/\/id.crossref.org\/issn\/0255-0857","issn-type":"print"},{"key":"key-10.4103\/0974-2727.180797-5","first-page":"297","volume-title":"Disseminated histoplamosis","author":"Joshi","year":"2006","journal-title":"Indian J Med Microbiol","ISSN":"https:\/\/id.crossref.org\/issn\/0255-0857","issn-type":"print"},{"key":"key-10.4103\/0974-2727.180797-6","first-page":"185","volume-title":"Disseminated histoplasmosis","author":"Subramanian","year":"2005","journal-title":"J Assoc Physicians India"},{"key":"key-10.4103\/0974-2727.180797-7","first-page":"35","volume-title":"Disseminated histoplasmosis with conjunctival involvement in an immunocompromised patient","author":"Shirali","year":"2010","journal-title":"Indian J Sex Transm Dis","ISSN":"https:\/\/id.crossref.org\/issn\/0253-7184","issn-type":"print"},{"key":"key-10.4103\/0974-2727.180797-8","first-page":"540","volume-title":"Histoplasmosis in eastern India: The tip of the iceberg?","author":"Goswami","year":"1999","journal-title":"Trans R Soc Trop Med Hyg"}],"container-title":["Journal of Laboratory Physicians"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.4103\/0974-2727.180797.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,24]],"date-time":"2023-12-24T03:14:17Z","timestamp":1703387657000},"score":1,"resource":{"primary":{"URL":"https:\/\/jlabphy.org\/disseminated-histoplasmosis-a-fatal-opportunistic-infection-in-disguise\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7]]},"references-count":8,"journal-issue":{"issue":"02","published-online":{"date-parts":[[2020,4,19]]},"published-print":{"date-parts":[[2016,7]]}},"URL":"https:\/\/doi.org\/10.4103\/0974-2727.180797","relation":{},"ISSN":["0974-2727","0974-7826"],"issn-type":[{"value":"0974-2727","type":"print"},{"value":"0974-7826","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,7]]}}}