{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,15]],"date-time":"2025-04-15T11:34:45Z","timestamp":1744716885017},"reference-count":22,"publisher":"Scientific Scholar","issue":"02","license":[{"start":{"date-parts":[[2020,2,19]],"date-time":"2020-02-19T00:00:00Z","timestamp":1582070400000},"content-version":"vor","delay-in-days":1054,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Lab Physicians"],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          PURPOSE: Group A streptococcal (GAS) pharyngitis is a common disease worldwide. We aimed to establish a pragmatic program as a clinical decision rule for GAS pharyngitis diagnosis.<\/jats:p><jats:p>\n          MATERIALS AND METHODS: This article derived from a research project on children aged 6\u201315 years. Five hundred and seventy-one children met the enrollment criteria on whom throat culture and validities of clinical findings were assessed in positive and negative throat culture groups.<\/jats:p><jats:p>\n          RESULTS: Positive GAS throat culture group included 99 (17.3%) patients with a positive culture. Negative GAS throat culture group included 472 (82.6%) patients. Exudate or enlarged tender nodes each one had 63% and 68% sensitivity and 31.5% and 37.5% specificity with a high percentage of negative predictive value (NPV) 80.54% and 85.09%, respectively. Sequence test revealed validities of exudate plus enlarged nodes at 43.62% sensitivity and 57.19% specificity with 83% NPV.<\/jats:p><jats:p>\n          CONCLUSIONS: High NPV of 83% indicated that similar prevalence in the absence of either exudate or enlarged tender lymph nodes. Probability of GAS negative throat cultures among children suspected of GAS pharyngitis was 83% and would correctly not receive inopportune antibiotics.<\/jats:p>","DOI":"10.4103\/0974-2727.199635","type":"journal-article","created":{"date-parts":[[2017,2,7]],"date-time":"2017-02-07T08:58:08Z","timestamp":1486457888000},"page":"116-120","source":"Crossref","is-referenced-by-count":3,"title":["A clinical decision rule for streptococcal pharyngitis management: An update"],"prefix":"10.25259","volume":"9","author":[{"given":"Hosain","family":"Nasirian","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Islamic Azad University, Tehran Medical Sciences Branch, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saeedeh","family":"TarvijEslami","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Islamic Azad University, Tehran Medical Sciences Branch, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esfandiar","family":"Matini","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Islamic Azad University, Tehran Medical Sciences Branch, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seyedehsara","family":"Bayesh","sequence":"additional","affiliation":[{"name":"Students' Research Committee, Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasaman","family":"Omaraee","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Roskilde Hospital, Roskilde, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2020,2,19]]},"reference":[{"key":"key-10.4103\/0974-2727.199635-1","first-page":"e86","volume-title":"Clinical practice guideline for the diagnosis and management of Group A streptococcal pharyngitis: 2012 update by the Infectious Diseases Society of America","author":"Shulman","year":"2012","journal-title":"Clin Infect Dis"},{"key":"key-10.4103\/0974-2727.199635-2","first-page":"383","volume-title":"Diagnosis and treatment of streptococcal pharyngitis","author":"Choby","year":"2009","journal-title":"Am Fam Physician"},{"key":"key-10.4103\/0974-2727.199635-3","first-page":"648","volume-title":"Streptococcal pharyngitis","author":"Wessels","year":"2011","journal-title":"New England Journal of Medicine"},{"key":"key-10.4103\/0974-2727.199635-4","first-page":"1016","volume-title":"Treatment of children with rheumatic heart disease in Sub-Saharan Africa by overseas' medical missions: Challenges left behind","author":"Tefera","year":"2014","journal-title":"J Cardiol Clin Res"},{"key":"key-10.4103\/0974-2727.199635-5","first-page":"e557","volume-title":"Prevalence of streptococcal pharyngitis and streptococcal carriage in children: A meta-analysis","author":"Shaikh","year":"2010","journal-title":"Pediatrics"},{"key":"key-10.4103\/0974-2727.199635-6","unstructured":"Pickering LK, Baker CJ, Kimberlin DW, Long SS. Group A streptococcal infection. In: Report of the Committee on Infectious Diseases. Red Book. 28th ed. Elk Grove Village, IL: American Academy of Pediatrics; 2009. p. 616-7."},{"key":"key-10.4103\/0974-2727.199635-7","doi-asserted-by":"crossref","unstructured":"Gerber MA. Group A Streptococcus. In: Kliegman RM, Stanton BF, Geme ST, Schor NF, Behrman RE, editors. Nelson Text Book of Pediatrics. 19th ed. Philadelphia: Elsevier; 2011. p. 914-24.","DOI":"10.1016\/B978-1-4377-0755-7.00176-7"},{"key":"key-10.4103\/0974-2727.199635-8","first-page":"77","volume-title":"Re-evaluation of antibiotic treatment of streptococcal pharyngitis","author":"Baltimore","year":"2010","journal-title":"Curr Opin Pediatr"},{"key":"key-10.4103\/0974-2727.199635-9","doi-asserted-by":"crossref","unstructured":"Bisno AL, Gerber MA, Gwaltney JM Jr., Kaplan EL, Schwartz RH; Infectious Diseases Society of America. Practice guidelines for the diagnosis and management of Group A streptococcal pharyngitis. Infectious Diseases Society of America. Clin Infect Dis 2002;35:113-25.","DOI":"10.1086\/340949"},{"key":"key-10.4103\/0974-2727.199635-10","first-page":"1038","volume-title":"A clinical decision rule for management of streptococcal pharyngitis in low-resource settings","author":"Steinhoff","year":"2005","journal-title":"Acta Paediatr"},{"key":"key-10.4103\/0974-2727.199635-11","first-page":"e1607","volume-title":", Van Melderen L, de Aguiar E, Vanderpas J, Vergison A.Pharyngitis in low-resources settings: A pragmatic clinical approach to reduce unnecessary antibiotic use","author":"Smeesters","year":"2006","journal-title":"Pediatrics"},{"key":"key-10.4103\/0974-2727.199635-12","first-page":"439","volume-title":"Rheumatic heart disease in developing countries","author":"Carapetis","year":"2007","journal-title":"N Engl J Med"},{"key":"key-10.4103\/0974-2727.199635-13","first-page":"185","volume-title":"Comparing performance of amoxicillin and intramuscular benzathine penicillin in relieving manifestations of streptococcal pharyngitis in children","author":"Eslami","year":"2014","journal-title":"Ghana Med J"},{"key":"key-10.4103\/0974-2727.199635-14","first-page":"1066","volume-title":"Evaluation of the WHO clinical decision rule for streptococcal pharyngitis","author":"Rimoin","year":"2005","journal-title":"Arch Dis Child"},{"key":"key-10.4103\/0974-2727.199635-15","first-page":"241","volume-title":"Throat culture is necessary after negative rapid antigen detection tests","author":"Mirza","year":"2007","journal-title":"Clin Pediatr (Phila)"},{"key":"key-10.4103\/0974-2727.199635-16","doi-asserted-by":"crossref","unstructured":"Le Marechal F, Martinot A, Duhamel A, Pruvost I, Dubos F. Streptococcal pharyngitis in children: A meta-analysis of clinical decision rules and their clinical variables. BMJ Open 2013;3. pii: e001482.","DOI":"10.1136\/bmjopen-2012-001482"},{"key":"key-10.4103\/0974-2727.199635-17","first-page":"609","volume-title":"Diagnosis and management of pharyngitis in a pediatric population based on cost-effectiveness and projected health outcomes","author":"Van","year":"2006","journal-title":"Pediatrics"},{"key":"key-10.4103\/0974-2727.199635-18","first-page":"383","volume-title":"Associations between procalcitonin and markers of bacterial sepsis","author":"Patil","year":"2012","journal-title":"Medicina (Kaunas)"},{"key":"key-10.4103\/0974-2727.199635-19","first-page":"687","volume-title":"Performance of a predictive model for streptococcal pharyngitis in children","author":"Attia","year":"2001","journal-title":"Arch Pediatr Adolesc Med"},{"key":"key-10.4103\/0974-2727.199635-20","first-page":"377","volume-title":"The validity of diagnostic criteria for streptococcal pharyngitis in integrated management of childhood illness (IMCI) guidelines","author":"Sahin","year":"2003","journal-title":"J Trop Pediatr"},{"key":"key-10.4103\/0974-2727.199635-21","first-page":"918","volume-title":"Effectiveness of clinical guidelines for the presumptive treatment of streptococcal pharyngitis in Egyptian children","author":"Steinhoff","year":"1997","journal-title":"Lancet"},{"key":"key-10.4103\/0974-2727.199635-22","first-page":"1584","volume-title":"Efficacy of an evidence-based clinical decision support in primary care practices: A randomized clinical trial","author":"McGinn","year":"2013","journal-title":"JAMA Intern Med"}],"container-title":["Journal of Laboratory Physicians"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.4103\/0974-2727.199635.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,24]],"date-time":"2023-12-24T08:14:34Z","timestamp":1703405674000},"score":1,"resource":{"primary":{"URL":"https:\/\/jlabphy.org\/a-clinical-decision-rule-for-streptococcal-pharyngitis-management-an-update\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4]]},"references-count":22,"journal-issue":{"issue":"02","published-online":{"date-parts":[[2020,2,19]]},"published-print":{"date-parts":[[2017,4]]}},"URL":"https:\/\/doi.org\/10.4103\/0974-2727.199635","relation":{},"ISSN":["0974-2727","0974-7826"],"issn-type":[{"value":"0974-2727","type":"print"},{"value":"0974-7826","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,4]]}}}