{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T17:37:43Z","timestamp":1792085863687,"version":"4.4.0"},"reference-count":24,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Global Infect Dis"],"published-print":{"date-parts":[[2017]]},"DOI":"10.4103\/0974-777x.192967","type":"journal-article","created":{"date-parts":[[2016,10,24]],"date-time":"2016-10-24T06:43:57Z","timestamp":1477291437000},"page":"3","source":"Crossref","is-referenced-by-count":15,"title":["Utility of loop-mediated isothermal amplification assay, polymerase chain reaction, and elisa for diagnosis of leptospirosis in South Indian patients"],"prefix":"10.4103","volume":"9","author":[{"given":"JohnAntony Jude","family":"Prakash","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mallika","family":"Sengupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"AbhilashKundavaram Paul","family":"Prabhakar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sowmya","family":"Satyendra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Thambu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"OoriapadickalCherian","family":"Abraham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veeraraghavan","family":"Balaji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua-Wei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chien-Chung","family":"Chao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei-Mei","family":"Ching","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"key-10.4103\/0974-777X.192967-1","first-page":"296","volume-title":"Leptospirosis","author":"Levett","year":"2001","journal-title":"Clin Microbiol Rev"},{"key":"key-10.4103\/0974-777X.192967-2","doi-asserted-by":"crossref","unstructured":"Smythe L, Adler B, Hartskeerl RA, Galloway RL, Turenne CY, Levett PN, et al. Classification of Leptospira genomospecies 1, 3, 4 and 5 as Leptospira alstonii sp. nov. Leptospira vanthielii sp. nov. Leptospira terpstrae sp. nov. and Leptospira yanagawae sp. nov. respectively. Int J Syst Evol Microbiol 2013;63(Pt 5):1859-62.","DOI":"10.1099\/ijs.0.047324-0"},{"key":"key-10.4103\/0974-777X.192967-3","first-page":"1413","volume-title":"Leptospira as an emerging pathogen: A review of its biology, pathogenesis and host immune responses","author":"Evangelista","year":"2010","journal-title":"Future Microbiol"},{"key":"key-10.4103\/0974-777X.192967-4","first-page":"178","volume-title":"Leptospirosis in India and the rest of the world","author":"Sambasiva","year":"2003","journal-title":"Braz J Infect Dis"},{"key":"key-10.4103\/0974-777X.192967-5","first-page":"111","volume-title":"Diagnosis of acute leptospirosis","author":"Toyokawa","year":"2011","journal-title":"Expert Rev Anti Infect Ther"},{"key":"key-10.4103\/0974-777X.192967-6","first-page":"614","volume-title":"Accuracy of loop-mediated isothermal amplification for diagnosis of human leptospirosis in Thailand","author":"Sonthayanon","year":"2011","journal-title":"Am J Trop Med Hyg"},{"key":"key-10.4103\/0974-777X.192967-7","first-page":"322","volume-title":"Fool's gold: Why imperfect reference tests are undermining the evaluation of novel diagnostics: A reevaluation of 5 diagnostic tests for leptospirosis","author":"Limmathurotsakul","year":"2012","journal-title":"Clin Infect Dis"},{"key":"key-10.4103\/0974-777X.192967-8","first-page":"e16236","volume-title":"Diagnostic accuracy of real-time PCR assays targeting 16S rRNA and lipL32 genes for human leptospirosis in Thailand: A case-control study","author":"Thaipadungpanit","year":"2011","journal-title":"PLoS One"},{"key":"key-10.4103\/0974-777X.192967-9","first-page":"1699","volume-title":"Polymerase chain reaction in comparison with serological tests for early diagnosis of human leptospirosis","author":"de","year":"2006","journal-title":"Trop Med Int Health"},{"key":"key-10.4103\/0974-777X.192967-10","first-page":"e7093","volume-title":"Development and validation of a real-time PCR for detection of pathogenic Leptospira species in clinical materials","author":"Ahmed","year":"2009","journal-title":"PLoS One"},{"key":"key-10.4103\/0974-777X.192967-11","first-page":"338","volume-title":"Molecular detection and speciation of pathogenic Leptospira spp.in blood from patients with culture-negative leptospirosis","author":"Boonsilp","year":"2011","journal-title":"BMC Infect Dis"},{"key":"key-10.4103\/0974-777X.192967-12","first-page":"E63","volume-title":"Loop-mediated isothermal amplification of DNA","author":"Notomi","year":"2000","journal-title":"Nucleic Acids Res"},{"key":"key-10.4103\/0974-777X.192967-13","first-page":"407","volume-title":"Loop mediated isothermal amplification (LAMP): A new generation of innovative gene amplification technique; perspectives in clinical diagnosis of infectious diseases","author":"Parida","year":"2008","journal-title":"Rev Med Virol"},{"key":"key-10.4103\/0974-777X.192967-14","first-page":"237","volume-title":"Application of a loop-mediated isothermal amplification method for the detection of pathogenic Leptospira","author":"Lin","year":"2009","journal-title":"Diagn Microbiol Infect Dis"},{"key":"key-10.4103\/0974-777X.192967-15","first-page":"545","volume-title":"Leptospirosis \u2013 An overview","author":"Dutta","year":"2005","journal-title":"J Assoc Physicians India"},{"key":"key-10.4103\/0974-777X.192967-16","first-page":"263","volume-title":"Leptospirosis: Current situation and trends of specific laboratory tests","author":"Schreier","year":"2013","journal-title":"Expert Rev Clin Immunol"},{"key":"key-10.4103\/0974-777X.192967-17","first-page":"678","volume-title":"Diagnosis of leptospirosis utilizing modified Faine's criteria","author":"Shivakumar","year":"2004","journal-title":"J Assoc Physicians India"},{"key":"key-10.4103\/0974-777X.192967-18","first-page":"147173","volume-title":"Highly sensitive loop-mediated isothermal amplification for the detection of Leptospira","author":"Chen","year":"2015","journal-title":"Int J Bacteriol"},{"key":"key-10.4103\/0974-777X.192967-19","unstructured":"World Health Organization. Human Leptospirosis: Guidance for Diagnosis, Surveillance and Control; 2003. Available from: http:\/\/www.who.int\/csr\/don\/en\/WHO_CDS_CSR_EPH_2002.23.pdf. [Last cited on 2016 Jan 18]."},{"key":"key-10.4103\/0974-777X.192967-20","first-page":"737","volume-title":"Leptospirosis: An institutional experience","author":"Datta","year":"2011","journal-title":"J Indian Med Assoc"},{"key":"key-10.4103\/0974-777X.192967-21","first-page":"785","volume-title":"Serological & molecular approaches for diagnosis of leptospirosis in a tertiary care hospital in North India: A 10-year study","author":"Chaudhry","year":"2013","journal-title":"Indian J Med Res","ISSN":"https:\/\/id.crossref.org\/issn\/0971-5916","issn-type":"print"},{"key":"key-10.4103\/0974-777X.192967-22","first-page":"1001","volume-title":"Serologic evidence of human leptospirosis in and around Kolkata, India: A clinico-epidemiological study","author":"DebMandal","year":"2011","journal-title":"Asian Pac J Trop Med"},{"key":"key-10.4103\/0974-777X.192967-23","first-page":"2072","volume-title":"A new loop-mediated isothermal amplification method for rapid, simple, and sensitive detection of Leptospira spp.in urine","author":"Koizumi","year":"2012","journal-title":"J Clin Microbiol"},{"key":"key-10.4103\/0974-777X.192967-24","first-page":"245","volume-title":"Laboratory diagnosis of leptospirosis: A challenge","author":"Musso","year":"2013","journal-title":"J Microbiol Immunol Infect"}],"container-title":["Journal of Global Infectious Diseases"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T13:28:27Z","timestamp":1786714107000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/0974-777X.192967"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":24,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017]]}},"alternative-id":["192967"],"URL":"https:\/\/doi.org\/10.4103\/0974-777x.192967","relation":{},"ISSN":["0974-777X"],"issn-type":[{"value":"0974-777X","type":"print"}],"subject":[],"published":{"date-parts":[[2017]]}}}