{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T19:33:40Z","timestamp":1778182420985,"version":"3.51.4"},"reference-count":34,"publisher":"Manuscript Technomedia LLP","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Phcog Res"],"published-print":{"date-parts":[[2016]]},"DOI":"10.4103\/0974-8490.178650","type":"journal-article","created":{"date-parts":[[2016,3,14]],"date-time":"2016-03-14T01:57:41Z","timestamp":1457920661000},"page":"1","source":"Crossref","is-referenced-by-count":16,"title":["Anti-\n                    <i>Leishmania<\/i>\n                    activity of osthole"],"prefix":"10.5530","volume":"8","author":[{"given":"ElahehKordzadeh","family":"Kermani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"SeyedEbrahim","family":"Sajjadi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"SeyedHossein","family":"Hejazi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reza","family":"Arjmand","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sedigheh","family":"Saberi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"AbbasAli","family":"Eskandarian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3478","reference":[{"key":"key-10.4103\/0974-8490.178650-1","unstructured":"World Health Organization. Control of the Leishmaniases. World Health Organization Technical Report Series 949. Geneva: World Health Organization; 2010. p. xii-xiii."},{"key":"key-10.4103\/0974-8490.178650-2","first-page":"150","volume-title":"Cutaneous leishmaniasis treatment","author":"Minodier","year":"2007","journal-title":"Travel Med Infect Dis"},{"key":"key-10.4103\/0974-8490.178650-3","first-page":"1337","volume-title":"Clinical status of agents being developed for leishmaniasis","author":"Berman","year":"2005","journal-title":"Expert Opin Investig Drugs"},{"key":"key-10.4103\/0974-8490.178650-4","first-page":"514","volume-title":"A review of natural products with antileishmanial activity","author":"Rocha","year":"2005","journal-title":"Phytomedicine"},{"key":"key-10.4103\/0974-8490.178650-5","first-page":"130","volume-title":"Coumarins from the fruits of Prangos ferulacea","author":"Abyshev","year":"1968","journal-title":"Chem Nat Compd"},{"key":"key-10.4103\/0974-8490.178650-6","first-page":"752","volume-title":"Coumarin from the roots and epigeal mass of Prangos acaulis","author":"Kuznetsova","year":"1979","journal-title":"Chem Nat Compd"},{"key":"key-10.4103\/0974-8490.178650-7","first-page":"19","volume-title":"Isolation and identification of osthol from the fruits and essential oil composition of the leaves of Prangos asperula Boiss","author":"Sajjadi","year":"2009","journal-title":"Res Pharm Sci"},{"key":"key-10.4103\/0974-8490.178650-8","first-page":"674","volume-title":"A new bisabolene derivative from the essential oil of Prangos uechtritzii fruits","author":"Baser","year":"2000","journal-title":"Planta Med"},{"key":"key-10.4103\/0974-8490.178650-9","first-page":"193","volume-title":"Biological activities of a Turkish medicinal plant, Prangos platychlaena","author":"Ulubelen","year":"1995","journal-title":"J Ethnopharmacol"},{"key":"key-10.4103\/0974-8490.178650-10","first-page":"297","volume-title":"Osthole: A promising lead compound for drug discovery from a traditional Chinese medicine (TCM)","author":"You","year":"2009","journal-title":"Nat Prod Commun"},{"key":"key-10.4103\/0974-8490.178650-11","first-page":"013","volume-title":"An in vitro test of killing effect of osthol against Trichomonas vaginalis","author":"Xia","year":"2008","journal-title":"China Trop Med"},{"key":"key-10.4103\/0974-8490.178650-12","first-page":"195","volume-title":"Anthelmintic activity of the crude extracts, fractions, and osthole from radix Angelicae pubescentis against Dactylogyrus intermedius in goldfish (Carassius auratus) in vivo","author":"Wang","year":"2011","journal-title":"Parasitol Res"},{"key":"key-10.4103\/0974-8490.178650-13","unstructured":"Mehregan I, Sajjadi SE. Chemical composition of the essential oil of Prangos asperula Boiss. Subsp. Haussknechtii (BOISS.) Herrnst. Etheyn fruits. Daru J Pharm Sci 2003;11:79-81."},{"key":"key-10.4103\/0974-8490.178650-14","first-page":"508","volume-title":"In vivoand in vitro control of Leishmania mexicana due to garlic-induced NO production","author":"Gamboa-Le\u00f3n","year":"2007","journal-title":"Scand J Immunol"},{"key":"key-10.4103\/0974-8490.178650-15","doi-asserted-by":"crossref","unstructured":"Zhang X, Goncalves R, Mosser DM. The isolation and characterization of murine macrophages. Curr Protoc Immunol 2008;83:1-14","DOI":"10.1002\/0471142735.im1401s83"},{"key":"key-10.4103\/0974-8490.178650-16","first-page":"715","volume-title":"Anti-leishmanial activity of crude extract and coumarin from Calophyllum brasiliense leaves against Leishmania amazonensis","author":"Brenzan","year":"2007","journal-title":"Parasitol Res"},{"key":"key-10.4103\/0974-8490.178650-17","first-page":"149707","volume-title":"In vitroand in vivo antileishmanial effects of Pistacia khinjuk against Leishmania tropica and Leishmania major","author":"Ezatpour","year":"2015","journal-title":"Evid Based Complement Alternat Med"},{"key":"key-10.4103\/0974-8490.178650-18","first-page":"266","volume-title":"A microplate assay for Leishmania amazonensis promastigotes expressing multimeric green fluorescent protein","author":"Chan","year":"2003","journal-title":"Parasitol Res"},{"key":"key-10.4103\/0974-8490.178650-19","first-page":"1196","volume-title":"Intramuscular and topical treatment of cutaneous leishmaniasis lesions in mice infected with Leishmania amazonensis using coumarin (-) mammea A\/BB","author":"Tiuman","year":"2012","journal-title":"Phytomedicine"},{"key":"key-10.4103\/0974-8490.178650-20","first-page":"3395","volume-title":"Natural products as a source for treating neglected parasitic diseases","author":"Ndjonka","year":"2013","journal-title":"Int J Mol Sci"},{"key":"key-10.4103\/0974-8490.178650-21","first-page":"996","volume-title":"Inhibition of platelet thromboxane formation and phosphoinositides breakdown by osthole from Angelica pubescens","author":"Ko","year":"1989","journal-title":"Thromb Haemost"},{"key":"key-10.4103\/0974-8490.178650-22","first-page":"309","volume-title":"Osthole, a potential antidiabetic agent, alleviates hyperglycemia in db\/db mice","author":"Liang","year":"2009","journal-title":"Chem Biol Interact"},{"key":"key-10.4103\/0974-8490.178650-23","first-page":"1234","volume-title":"Osthole stimulates osteoblast differentiation and bone formation by activation of beta-catenin-BMP signaling","author":"Tang","year":"2010","journal-title":"J Bone Miner Res"},{"key":"key-10.4103\/0974-8490.178650-24","first-page":"1430","volume-title":"Effects of osthole on migration and invasion in breast cancer cells","author":"Yang","year":"2010","journal-title":"Biosci Biotechnol Biochem"},{"key":"key-10.4103\/0974-8490.178650-25","first-page":"206","volume-title":"Neuroprotective effect of osthole against acute ischemic stroke on middle cerebral ischemia occlusion in rats","author":"Chao","year":"2010","journal-title":"Brain Res"},{"key":"key-10.4103\/0974-8490.178650-26","first-page":"638","volume-title":"Osthole improves alcohol-induced fatty liver in mice by reduction of hepatic oxidative stress","author":"Zhang","year":"2011","journal-title":"Phytother Res"},{"key":"key-10.4103\/0974-8490.178650-27","first-page":"1012","volume-title":"Coumarins from Galipea panamensis and their activity against Leishmania panamensis","author":"Arango","year":"2010","journal-title":"J Nat Prod"},{"key":"key-10.4103\/0974-8490.178650-28","first-page":"375","volume-title":"Antileishmanial activity of furoquinolines and coumarins from Helietta apiculata","author":"Ferreira","year":"2010","journal-title":"Phytomedicine"},{"key":"key-10.4103\/0974-8490.178650-29","first-page":"554","volume-title":"Sesquiterpene coumarins from Ferula szowitsiana and in vitro antileishmanial activity of 7-prenyloxycoumarins against promastigotes","author":"Iranshahi","year":"2007","journal-title":"Phytochemistry"},{"key":"key-10.4103\/0974-8490.178650-30","first-page":"380","volume-title":"Activity of extracts and coumarins from the leaves of Calophyllum brasiliense on Leishmania braziliensis","author":"Brenzan","year":"2008","journal-title":"Pharm Biol"},{"key":"key-10.4103\/0974-8490.178650-31","first-page":"116","volume-title":"Antibacterial and anticoagulant activities of coumarins isolated from the flowers of Magydaris tomentosa","author":"Rosselli","year":"2007","journal-title":"Planta Med"},{"key":"key-10.4103\/0974-8490.178650-32","first-page":"23","volume-title":"DNA microarray gene expression profile of Mycobacterium tuberculosis when exposed to osthole","author":"Wei","year":"2013","journal-title":"Pol J Microbiol"},{"key":"key-10.4103\/0974-8490.178650-33","first-page":"52","volume-title":"Cytotoxic effects of dimethyl sulphoxide (DMSO) on cochlear organotypic cultures","author":"Qi","year":"2008","journal-title":"Hear Res"},{"key":"key-10.4103\/0974-8490.178650-34","first-page":"1600","volume-title":"Evaluation of the cytotoxicity effect of dimethyl sulfoxide (DMSO) on Caco2\/TC7 colon tumor cell cultures","author":"Da","year":"2002","journal-title":"Biol Pharm Bull"}],"container-title":["Pharmacognosy Research"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T09:39:26Z","timestamp":1769593166000},"score":1,"resource":{"primary":{"URL":"https:\/\/phcogres.com\/article\/8\/5s\/s1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":34,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2016]]}},"alternative-id":["178650"],"URL":"https:\/\/doi.org\/10.4103\/0974-8490.178650","relation":{},"ISSN":["0974-8490"],"issn-type":[{"value":"0974-8490","type":"print"}],"subject":[],"published":{"date-parts":[[2016]]}}}