{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T20:31:16Z","timestamp":1786653076366,"version":"build-2736575974"},"reference-count":41,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Middle East Afr J Ophthalmol"],"published-print":{"date-parts":[[2015]]},"DOI":"10.4103\/0974-9233.167815","type":"journal-article","created":{"date-parts":[[2015,10,22]],"date-time":"2015-10-22T01:06:21Z","timestamp":1445475981000},"page":"421","source":"Crossref","is-referenced-by-count":20,"title":["Review of ocular manifestations of nevoid basal cell carcinoma syndrome: What an ophthalmologist needs to know"],"prefix":"10.4103","volume":"22","author":[{"given":"Pete","family":"Setabutr","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JudyJ","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliana","family":"Sartori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"VinayK","family":"Aakalu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"key-10.4103\/0974-9233.167815-1","first-page":"908","volume-title":"Multiple nevoid basal-cell epithelioma, jaw cysts and bifid rib.A syndrome","author":"Gorlin","year":"1960","journal-title":"N Engl J Med"},{"key":"key-10.4103\/0974-9233.167815-2","first-page":"162","volume-title":"On the doctrine of skin tumors","author":"Jarisch","year":"1894","journal-title":"Arch Dermatol Syphilol"},{"key":"key-10.4103\/0974-9233.167815-3","first-page":"477","volume-title":"Multiple benign cystic epitheliomas","author":"White","year":"1894","journal-title":"J Cutan Genitourin Dis"},{"key":"key-10.4103\/0974-9233.167815-4","first-page":"299","volume-title":"Clinical manifestations in 105 persons with nevoid basal cell carcinoma syndrome","author":"Kimonis","year":"1997","journal-title":"Am J Med Genet"},{"key":"key-10.4103\/0974-9233.167815-5","first-page":"32","volume-title":"Nevoid basal cell carcinoma syndrome (Gorlin syndrome)","author":"Lo","year":"2008","journal-title":"Orphanet J Rare Dis"},{"key":"key-10.4103\/0974-9233.167815-6","first-page":"RA145","volume-title":"Gorlin-Goltz syndrome: A medical condition requiring a multidisciplinary approach","author":"Kiwilsza","year":"2012","journal-title":"Med Sci Monit"},{"key":"key-10.4103\/0974-9233.167815-7","first-page":"581","volume-title":"Location of gene for gorlin syndrome","author":"Farndon","year":"1992","journal-title":"Lancet"},{"key":"key-10.4103\/0974-9233.167815-8","first-page":"643","volume-title":"Brain tumours and the occurrence of severe invasive basal cell carcinoma in first degree relatives with Gorlin syndrome","author":"Evans","year":"1991","journal-title":"Br J Neurosurg"},{"key":"key-10.4103\/0974-9233.167815-9","first-page":"964","volume-title":"Nevoid basal cell carcinoma syndrome.A 15-year follow-up of cases in Ottawa and the Ottawa Valley","author":"Pratt","year":"1987","journal-title":"J Am Acad Dermatol"},{"key":"key-10.4103\/0974-9233.167815-10","first-page":"34","volume-title":"Nevoid basal cell carcinoma syndrome.Clinical findings in 37 Italian affected individuals","author":"Lo","year":"1999","journal-title":"Clin Genet"},{"key":"key-10.4103\/0974-9233.167815-11","first-page":"282","volume-title":"Nevoid basal cell carcinoma syndrome: Review of 118 affected individuals","author":"Shanley","year":"1994","journal-title":"Am J Med Genet"},{"key":"key-10.4103\/0974-9233.167815-12","first-page":"351","volume-title":"Nationwide survey of nevoid basal cell carcinoma syndrome in Japan revealing the low frequency of basal cell carcinoma","author":"Endo","year":"2012","journal-title":"Am J Med Genet A"},{"key":"key-10.4103\/0974-9233.167815-13","first-page":"458","volume-title":"Nevoid basal cell carcinoma syndrome: A retrospective analysis of 33 affected Korean individuals","author":"Ahn","year":"2004","journal-title":"Int J Oral Maxillofac Surg"},{"key":"key-10.4103\/0974-9233.167815-14","first-page":"723","volume-title":"Periocular basal cell carcinoma in adults 35 years of age and younger","author":"Nerad","year":"1988","journal-title":"Am J Ophthalmol"},{"key":"key-10.4103\/0974-9233.167815-15","first-page":"426","volume-title":"Nevoid basal cell carcinoma syndrome: Our experience in a pediatric hospital","author":"Samela","year":"2013","journal-title":"Actas Dermosifiliogr"},{"key":"key-10.4103\/0974-9233.167815-16","first-page":"363","volume-title":"Nevoid basal cell carcinoma syndrome in a black child","author":"Hall","year":"1998","journal-title":"J Am Acad Dermatol"},{"key":"key-10.4103\/0974-9233.167815-17","first-page":"259","volume-title":"Review of patients with basal cell nevus syndrome","author":"Taylor","year":"2006","journal-title":"Ophthal Plast Reconstr Surg"},{"key":"key-10.4103\/0974-9233.167815-18","first-page":"147","volume-title":"Infundibulocystic basal cell carcinoma of the eyelid in basal cell nevus syndrome","author":"Belliveau","year":"2010","journal-title":"Ophthal Plast Reconstr Surg"},{"key":"key-10.4103\/0974-9233.167815-19","first-page":"321","volume-title":"Gorlin syndrome (nevoid basal cell carcinoma syndrome)","author":"De-Domingo","year":"2008","journal-title":"Arch Soc Esp Oftalmol"},{"key":"key-10.4103\/0974-9233.167815-20","first-page":"77","volume-title":"Myelinated retinal nerve fibers: Prevalence, location and effect on visual acuity","author":"Kodama","year":"1990","journal-title":"Ophthalmologica"},{"key":"key-10.4103\/0974-9233.167815-21","first-page":"1833","volume-title":"Medullated nerve fibers.A sign of multiple basal cell nevi (Gorlin's) syndrome","author":"De","year":"1985","journal-title":"Arch Ophthalmol"},{"key":"key-10.4103\/0974-9233.167815-22","first-page":"157","volume-title":"Adult form of basal cell naevus syndrome: A family study","author":"Khoubesserian","year":"1981","journal-title":"J Neurol"},{"key":"key-10.4103\/0974-9233.167815-23","first-page":"113","volume-title":"Gorlin's syndrome.Case report","author":"Salati","year":"1997","journal-title":"Eur J Ophthalmol"},{"key":"key-10.4103\/0974-9233.167815-24","first-page":"346","volume-title":"Bilateral epiretinal membranes in gorlin syndrome associated with a novel PTCH mutation","author":"Scott","year":"2007","journal-title":"Am J Ophthalmol"},{"key":"key-10.4103\/0974-9233.167815-25","first-page":"516","volume-title":"Identification of a novel mutation in the PTCH gene in a patient with Gorlin-goltz syndrome with unusual ocular disorders","author":"Romano","year":"2011","journal-title":"Eur J Ophthalmol"},{"key":"key-10.4103\/0974-9233.167815-26","first-page":"1004","volume-title":"Photo essay: Combined hamartoma of the retina and retinal pigment epithelium in Gorlin syndrome","author":"De","year":"2000","journal-title":"Arch Ophthalmol"},{"key":"key-10.4103\/0974-9233.167815-27","first-page":"3269","volume-title":"Abnormalities of the vitreoretinal interface caused by dysregulated Hedgehog signaling during retinal development","author":"Black","year":"2003","journal-title":"Hum Mol Genet"},{"key":"key-10.4103\/0974-9233.167815-28","first-page":"988","volume-title":"Gorlin syndrome: The PTCH gene links ocular developmental defects and tumour formation","author":"Ragge","year":"2005","journal-title":"Br J Ophthalmol"},{"key":"key-10.4103\/0974-9233.167815-29","first-page":"1115","volume-title":"Basal cell carcinoma of the eyelid associated with Gorlin-Goltz syndrome","author":"Honavar","year":"2001","journal-title":"Ophthalmology"},{"key":"key-10.4103\/0974-9233.167815-30","first-page":"280","volume-title":"Subconjunctival epidermoid cysts in Gorlin-Goltz syndrome","author":"De","year":"2014","journal-title":"Orbit"},{"key":"key-10.4103\/0974-9233.167815-31","first-page":"887","volume-title":"Ocular hypertelorism, facial basal cell carcinomas, and multiple odontogenic keratocysts of the jaws","author":"Friedlander","year":"1988","journal-title":"J Am Dent Assoc"},{"key":"key-10.4103\/0974-9233.167815-32","first-page":"1023","volume-title":"Nevoid basal cell carcinoma syndrome.A review and case report of a patient with unilateral basal cell nevus syndrome","author":"Gutierrez","year":"1986","journal-title":"J Am Acad Dermatol"},{"key":"key-10.4103\/0974-9233.167815-33","first-page":"1","volume-title":"Gorlin-goltz syndrome: A rare case report","author":"Mohan","year":"2013","journal-title":"Br Med J Case Rep"},{"key":"key-10.4103\/0974-9233.167815-34","first-page":"A4829","volume-title":"Manifestations of Gorlin-Goltz syndrome","author":"Larsen","year":"2014","journal-title":"Dan Med J"},{"key":"key-10.4103\/0974-9233.167815-35","first-page":"41","volume-title":"Multiple intracranial meningiomas causing papilledema and visual loss in a patient with nevoid Basal cell carcinoma syndrome","author":"Pribila","year":"2008","journal-title":"J Neuroophthalmol"},{"key":"key-10.4103\/0974-9233.167815-36","first-page":"57","volume-title":"Novel mutations in the patched gene in basal cell nevus syndrome","author":"Lam","year":"2002","journal-title":"Mol Genet Metab"},{"key":"key-10.4103\/0974-9233.167815-37","first-page":"87","volume-title":"Targeted therapy for orbital and periocular basal cell carcinoma and squamous cell carcinoma","author":"Yin","year":"2013","journal-title":"Ophthal Plast Reconstr Surg"},{"key":"key-10.4103\/0974-9233.167815-38","first-page":"917","volume-title":"Nevoid basal-cell syndrome: Literature review and case report in a family","author":"Jos\u00e9","year":"1995","journal-title":"Sao Paulo Med J"},{"key":"key-10.4103\/0974-9233.167815-39","first-page":"626","volume-title":"Consensus recommendations for the treatment of basal cell carcinomas in Gorlin syndrome with topical methylaminolaevulinate-photodynamic therapy","author":"Basset-Seguin","year":"2014","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"key-10.4103\/0974-9233.167815-40","first-page":"1591","volume-title":"Vismodegib for periocular and orbital basal cell carcinoma","author":"Gill","year":"2013","journal-title":"JAMA Ophthalmol"},{"key":"key-10.4103\/0974-9233.167815-41","first-page":"235","volume-title":"Retinoids in the chemoprevention of non-melanoma skin cancers: Why, when and how","author":"Bettoli","year":"2013","journal-title":"J Dermatolog Treat"}],"container-title":["Middle East African Journal of Ophthalmology"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:31:04Z","timestamp":1786649464000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/0974-9233.167815"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":41,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015]]}},"alternative-id":["167815"],"URL":"https:\/\/doi.org\/10.4103\/0974-9233.167815","relation":{},"ISSN":["0974-9233"],"issn-type":[{"value":"0974-9233","type":"print"}],"subject":[],"published":{"date-parts":[[2015]]}}}