{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:44:14Z","timestamp":1787071454039,"version":"build-2736575974"},"reference-count":26,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2012,8]]},"abstract":"<jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>The aim of this study was to determine the prevalence of hepatitis B virus and hepatitis C virus (HCV) infections in patients with oral lichen planus (OLP) and to compare it with that of general population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>A total of 60 patients were included in the study. Patients were selected from the outpatient department of Rama Dental College Research Centre, Kanpur, Uttar Pradesh. Thirty patients with OLP were included in Group 1. Thirty age- and sex-matched healthy patients with no history of oral or skin lesions were included in Group 2. Detailed case history, biopsy (the most representative site of the lesion is chosen for specimen), detection of hepatitis B surface antigen (HBsAg), and detection of anti-HCV antibody were carried out.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The serum of the entire study sample (Group 1 and Group 2) was tested for both hepatitis C antibodies and HBsAgs with the enzyme-linked immunosorbent assay (ELISA) test (using the third generation kit). It was found negative for both HBsAgs and hepatitis C antibodies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>In the present study, all the samples including OLP patients and healthy patients were seronegative for both hepatitis B (HBsAg) and hepatitis C (HCV antibody).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/0975-7406.100302","type":"journal-article","created":{"date-parts":[[2014,1,30]],"date-time":"2014-01-30T02:19:46Z","timestamp":1391048386000},"page":"S397-S405","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":19,"title":["Prevalence of hepatitis C and hepatitis B virus infection(s) in patients with oral lichen planus"],"prefix":"10.4103","volume":"4","author":[{"given":"Perumal","family":"Jayavelu","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillo Facial Surgery, Rama Dental College and Research Centre, Kanpur, UP, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thirumal","family":"Sambandan","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, Tamilnadu Government Dental College and Hospital, Chennai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20250922","first-page":"E40","article-title":"Functions of the cytokines in relation oral lichen planus-hepatitis C","volume":"10","author":"Femiano","year":"2005","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"R2-20250922","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/1471-5945-4-6","article-title":"Lichen planus and Hepatitis C: A case-control study","volume":"4","author":"Ghodsi","year":"2004","journal-title":"BMC Dermatology"},{"key":"R3-20250922","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/S1085-5629(97)80016-8","article-title":"Oral Lichen Planus: Epidemiology, Clinical, Characteristics, and Associated Diseases","volume":"16","author":"Lozanda-Nur","year":"1997","journal-title":"Seminars in Cutaneous Medicine and Surgery"},{"key":"R4-20250922","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.tripleo.2004.06.077","article-title":"Current controversies in oral lichen planus: Report of an international consensus meeting. Part 1. Viral infections and etiopathogenesis","volume":"100","author":"Lodi","year":"2005","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"R5-20250922","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1111\/j.1365-2133.1994.tb06905.x","article-title":"Oral lichen planus in childhood","volume":"131","author":"Scully","year":"1994","journal-title":"Br J Dermatol"},{"key":"R6-20250922","doi-asserted-by":"crossref","first-page":"89","DOI":"10.2334\/josnusd.49.89","article-title":"Oral lichen planus and lichenoid reaction: Etiopathogesis, dagnosis, management and malignant transformation","volume":"49","author":"Ismail","year":"2007","journal-title":"J Oral Sci"},{"key":"R7-20250922","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1177\/10454411980090010501","article-title":"Update on oral lichen planus -etiopathogenesis and management","volume":"9","author":"Scully","year":"1998","journal-title":"Crit Rev Oral Biol Med"},{"key":"R8-20250922","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/0190-9622(91)70241-S","article-title":"Lichen planus","volume":"25","author":"Boyd","year":"1991","journal-title":"J AM Acad Dermatol"},{"key":"R9-20250922","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1046\/j.0307-7772.2001.00516.x","article-title":"Clinical and pathological characteristics of oral lichen planus in hepatitis C positive and negative patients","volume":"27","author":"Romero","year":"2002","journal-title":"Clin Otolaryngol Allied Sci"},{"key":"R11-20250922","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1111\/j.1601-0825.1997.tb00016.x","article-title":"Hepatitis C virus infection and lichen planus: A short review","volume":"3","author":"Lodi","year":"1997","journal-title":"Oral Dis"},{"key":"R12-20250922","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1054\/bjom.2000.0335","article-title":"Oral lichen planus: A review","volume":"38","author":"Mollaoglu","year":"2000","journal-title":"Br J Oral Maxillofac Sur"},{"key":"R13-20250922","first-page":"14","article-title":"Oral lichen planus and hepatitis C virus: Is there real association?","volume":"15","author":"Al Robaee","year":"2006","journal-title":"Acta Dermatovenerol Alp Panonica Adriat"},{"key":"R14-20250922","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/j.ijid.2008.02.006","article-title":"The prevalence of hepatitis B virus and hepatitis C virus infection among patients with chronic liver disease in South India","volume":"12","author":"Saravanan","year":"2008","journal-title":"Int JInfect Dis"},{"key":"R15-20250922","doi-asserted-by":"crossref","first-page":"1446","DOI":"10.1002\/hep.1840360622","article-title":"Oral lichen Planus Pathogenesis: A Role for the HCV-Specific Cellular Immune Response","volume":"36","author":"Pilli","year":"2002","journal-title":"Hepatology"},{"key":"R16-20250922","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1111\/j.1600-0714.1990.tb00866.x","article-title":"Immunopathogenesis of oral lichen planus","volume":"19","author":"Walsh","year":"1990","journal-title":"J Oral Pathol Med"},{"key":"R17-20250922","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1111\/j.1600-0714.1985.tb00516.x","article-title":"Lichen planus: review and update on pathogenesis","volume":"14","author":"Scully","year":"1985","journal-title":"J Oral Pathol"},{"key":"R18-20250922","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1111\/j.1601-0825.2005.01142.x","article-title":"Oral lichen planus: clinical features and management","volume":"11","author":"Eisen","year":"2005","journal-title":"Oral Dis"},{"key":"R19-20250922","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1177\/10454411930040020101","article-title":"The therapy of oral lichen planus","volume":"4","author":"Eisen","year":"1993","journal-title":"Crit Rev Oral Biol Med"},{"key":"R20-20250922","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.tripleo.2003.11.010","article-title":"Hepatitis C virus and lichen planus: A review","volume":"98","author":"Chainani-Wu","year":"2004","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"R21-20250922","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1111\/j.1600-0714.1999.tb01988.x","article-title":"Oral lichen planus in patients infected or not infected with hepatitis C virus: The role of autoimmunity","volume":"28","author":"Carrozzo","year":"1999","journal-title":"J Oral Pathol Med"},{"key":"R22-20250922","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1001\/archdermatol.2009.200","article-title":"Hepatitis C Virus and Lichen Planus - A Reciprocal Association Determined by a Meta-analysis","volume":"145","author":"Shengyuan","year":"2009","journal-title":"Arch Dermatol"},{"key":"R23-20250922","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1309\/HDWCT36P0GMGP40V","article-title":"Oral Lichen Planus and Chronic Hepatitis C A Controversial Association","volume":"127","author":"de Mattos Camargo","year":"2007","journal-title":"Am J Clin Pathol"},{"key":"R24-20250922","article-title":"Prevalence of hepatitis B virus and hepatitis C virus among blood donors at a tertiary care hospital in India: A five-year study","author":"Meena","year":"2010","journal-title":"Transfusion"},{"key":"R25-20250922","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/j.tripleo.2004.11.017","article-title":"Prevalence of oral lichen planus in Brazilian patients with HCV infection","volume":"100","author":"Cunha","year":"2005","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"R26-20250922","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000018054","article-title":"Lichen planus as a Side Effect of HBV Vaccination","volume":"198","author":"Rebora","year":"1999","journal-title":"Dermatology"},{"key":"R27-20250922","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1046\/j.1525-1470.2002.00079.x","article-title":"Lichen Planus in Children: A Possible Complication of Hepatitis B Vaccines","volume":"19","author":"Limas","year":"2002","journal-title":"Pediatr Dermatol"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/01438291-201204002-00068","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:46:22Z","timestamp":1787067982000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/01438291-201204002-00068"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,8]]},"references-count":26,"journal-issue":{"issue":"Suppl 2","published-print":{"date-parts":[[2012]]}},"URL":"https:\/\/doi.org\/10.4103\/0975-7406.100302","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,8]]},"assertion":[{"value":"2011-12-01","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2012-01-26","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}