{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T13:21:39Z","timestamp":1792070499073,"version":"4.4.0"},"reference-count":29,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Contemp Clin Dent"],"published-print":{"date-parts":[[2013]]},"DOI":"10.4103\/0976-237x.111619","type":"journal-article","created":{"date-parts":[[2013,5,9]],"date-time":"2013-05-09T07:33:43Z","timestamp":1368084823000},"page":"54","source":"Crossref","is-referenced-by-count":22,"title":["Comparative analysis of hyaluronan gel and xanthan-based chlorhexidine gel, as adjunct to scaling and root planing with scaling and root planing alone in the treatment of chronic periodontitis: A preliminary study"],"prefix":"10.4103","volume":"4","author":[{"given":"VivekK","family":"Bains","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"AvinashSingh","family":"Chauhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vivek","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"GP","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SudhirS","family":"Patil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"key-10.4103\/0976-237X.111619-1","first-page":"257","volume-title":"A systematic review on the effects of the chlorhexidine chip when used as an adjunct to scaling and root planing in the treatment of chronic periodontitis","author":"Cosyn","year":"2006","journal-title":"J Periodontol"},{"key":"key-10.4103\/0976-237X.111619-2","first-page":"1479","volume-title":"Clinical, microbiologic, and biochemical effects of subgingival administration of a Xanthan-based chlorhexidine gel in the treatment of periodontitis: A randomized multicenter trial","author":"Paolantonio","year":"2009","journal-title":"J Periodontol"},{"key":"key-10.4103\/0976-237X.111619-3","first-page":"1493","volume-title":"Local delivery of hyaluronan as an adjunct to scaling and root planing in the treatment of chronic periodontitis","author":"Johannsen","year":"2009","journal-title":"J Periodontol"},{"key":"key-10.4103\/0976-237X.111619-4","first-page":"420","volume-title":"The short-term effects of treatment of chronic periodontitis on circulating levels of endotoxin, C-reactive protein, tumor necrosis factor-alpha, and interleukin-6","author":"Ide","year":"2004","journal-title":"J Periodontol"},{"key":"key-10.4103\/0976-237X.111619-5","first-page":"69","volume-title":"Evaluation of C-reactive protein and interleukin-6 in the peripheral blood of patients with chronic periodontitis","author":"Gani","year":"2009","journal-title":"J Indian Soc Periodontol","ISSN":"https:\/\/id.crossref.org\/issn\/0972-124X","issn-type":"print"},{"key":"key-10.4103\/0976-237X.111619-6","first-page":"1355","volume-title":"Effect of periodontitis and smoking on blood leukocytes and acute-phase proteins","author":"Fredriksson","year":"1999","journal-title":"J Periodontol"},{"key":"key-10.4103\/0976-237X.111619-7","first-page":"54","volume-title":"After scaling and root planing lower systemic inflammatory and thrombotic marker of cardiovascular risk","author":"Rai","year":"2007","journal-title":"Middle-East J Sci Res"},{"key":"key-10.4103\/0976-237X.111619-8","first-page":"1574","volume-title":"Non-surgical periodontal therapy lowers serum inflammatory markers: A pilot study","author":"Hussain","year":"2009","journal-title":"J Periodontol"},{"key":"key-10.4103\/0976-237X.111619-9","first-page":"201","volume-title":"White blood cell count in generalized aggressive periodontitis after non-surgical therapy","author":"Christan","year":"2002","journal-title":"J Clin Periodontol"},{"key":"key-10.4103\/0976-237X.111619-10","unstructured":"Spolsky VW. Epidemiology of gingival and periodontal diseases. In: Carranza FA, Newman MG, editors. Clinical Periodontology. 8 th ed. Banglore: Prism Books Pvt Ltd; 1996. p. 65."},{"key":"key-10.4103\/0976-237X.111619-11","first-page":"294","volume-title":"Periodontal therapy: A novel non-drug-induced experimental model to study human inflammation","author":"D\u2032Aiuto","year":"2004","journal-title":"J Periodontal Res"},{"key":"key-10.4103\/0976-237X.111619-12","first-page":"722","volume-title":"Efficiency of split-mouth designs","author":"Hujoel","year":"1990","journal-title":"J Clin Periodontol"},{"key":"key-10.4103\/0976-237X.111619-13","first-page":"25","volume-title":"Comparative evaluation of subgingivally delivered 10% doxycycline hyclate and xanthan-based chlorhexidine gels in the treatment of chronic periodontitis","author":"Gupta","year":"2008","journal-title":"J Contemp Dent Pract"},{"key":"key-10.4103\/0976-237X.111619-14","first-page":"47","volume-title":"Clinical evaluation of topical subgingival application of biodegradable xanthan based 1.5% chlorhexidine gel for treatment on periodontal pockets","author":"Kranti","year":"2010","journal-title":"J Adv Dent Res"},{"key":"key-10.4103\/0976-237X.111619-15","first-page":"1805","volume-title":"A systematic review on the effects of subgingival chlorhexidine gel administration in the treatment of chronic periodontitis","author":"Cosyn","year":"2005","journal-title":"J Periodontol"},{"key":"key-10.4103\/0976-237X.111619-16","first-page":"271","volume-title":"Clinical and microbiologic effects of subgingival controlled-release delivery of chlorhexidine chip in the treatment of periodontitis: A multicenter study","author":"Paolantonio","year":"2008","journal-title":"J Periodontol"},{"key":"key-10.4103\/0976-237X.111619-17","first-page":"245","volume-title":"Comparison of the antimicrobial effect of the application of chlorhexidine gel, amine fluoride gel and stannous fluoride gel in debrided periodontal pockets","author":"Oosterwaal","year":"1991","journal-title":"J Clin Periodontol"},{"key":"key-10.4103\/0976-237X.111619-18","first-page":"209","volume-title":"Subgingival utilization of a 1% chlorhexidine collagen gel for the treatment of periodontal pockets.A clinical and microbiological study","author":"Vinholis","year":"2001","journal-title":"Braz Dent J"},{"key":"key-10.4103\/0976-237X.111619-19","first-page":"1114","volume-title":"Clinical and microbiological effects of topical subgingival application of hyaluronic acid gel adjunctive to scaling and root planing in the treatment of chronic periodontitis","author":"Xu","year":"2004","journal-title":"J Periodontol"},{"key":"key-10.4103\/0976-237X.111619-20","first-page":"159","volume-title":"Treatment of gingivitis with hyaluronan","author":"Jentsch","year":"2003","journal-title":"J Clin Periodontol"},{"key":"key-10.4103\/0976-237X.111619-21","first-page":"531","volume-title":"The clinical application of hyaluronic acid in gingivitis therapy","author":"Pistorius","year":"2005","journal-title":"Quintessence Int"},{"key":"key-10.4103\/0976-237X.111619-22","first-page":"848","volume-title":"Systemic inflammation following non-surgical and surgical periodontal therapy","author":"Graziani","year":"2010","journal-title":"J Clin Periodontol"},{"key":"key-10.4103\/0976-237X.111619-23","first-page":"1528","volume-title":"Elevation of systemic markers related to cardiovascular diseases in the peripheral blood of periodontitis patients","author":"Loos","year":"2000","journal-title":"J Periodontol"},{"key":"key-10.4103\/0976-237X.111619-24","first-page":"38","volume-title":"One stage vs two stage non-surgical periodontal therapy and their effect on WBC count","author":"Sambashivaiah","year":"2010","journal-title":"Int J Clin Dent Sci"},{"key":"key-10.4103\/0976-237X.111619-25","doi-asserted-by":"crossref","unstructured":"Carranza FA, Camargo PM. The periodontal pocket. In. Newman MG, Takei HH, Klokevold PR, Carranza FA, editors. Carranza\u2032s Clinical Periodontology. 11 th ed. New Delhi: Elsevier Publication; 2011. p. 127-39.","DOI":"10.1016\/B978-1-4377-0416-7.00013-5"},{"key":"key-10.4103\/0976-237X.111619-26","first-page":"1229","volume-title":"Local application of hyaluronan gel in conjunction with periodontal surgery: A randomized controlled trial","author":"Fawzy","year":"2012","journal-title":"Clin Oral Investig"},{"key":"key-10.4103\/0976-237X.111619-27","first-page":"47","volume-title":"The effect of locally delivered xanthan-based CHLO-SITE gel with scaling and root planing in the treatment of chronic periodontitis: Microbial findings","author":"Abrishami","year":"2008","journal-title":"Dent Res J","ISSN":"https:\/\/id.crossref.org\/issn\/1735-3327","issn-type":"print"},{"key":"key-10.4103\/0976-237X.111619-28","first-page":"213","volume-title":"Efficacy of a chairside diagnostic test kit for estimation of C-reactive protein levels in periodontal disease","author":"Nagarale","year":"2010","journal-title":"J Indian Soc Periodontol","ISSN":"https:\/\/id.crossref.org\/issn\/0972-124X","issn-type":"print"},{"key":"key-10.4103\/0976-237X.111619-29","first-page":"315","volume-title":"Treatment of infrabony periodontal defects with esterified hyaluronic acid: Clinical report of 19 consecutive lesions","author":"Vanden","year":"2009","journal-title":"Int J Periodontics Restorative Dent"}],"container-title":["Contemporary Clinical Dentistry"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:24:01Z","timestamp":1786649041000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/0976-237X.111619"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":29,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013]]}},"alternative-id":["111619"],"URL":"https:\/\/doi.org\/10.4103\/0976-237x.111619","relation":{},"ISSN":["0976-237X"],"issn-type":[{"value":"0976-237X","type":"print"}],"subject":[],"published":{"date-parts":[[2013]]}}}