{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T23:51:29Z","timestamp":1789775489089,"version":"4.0.1"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2015,7]]},"abstract":"<jats:p>Williams syndrome is a multisystemic rare genetic disorder caused by deletion of 26\u201328 genes in the long arm of chromosome 7. It is characterized by developmental and physical abnormalities including congenital cardiovascular abnormalities, mental retardation, neurological features, growth deficiency, genitourinary manifestations, gastrointestinal problems, musculoskeletal problems, unique behavioral characteristics, and dental problems. Dental abnormalities include malocclusion, hypodontia, malformed teeth, taurodontism, pulp stones, increased space between teeth, enamel hypoplasia, and high prevalence of dental caries. Authors report a 17-year-old female patient with underlying Williams syndrome. Oral features and problems seen in the patient are listed. Malocclusion and screwdriver shaped teeth were noticed. Generalized widening of the periodontal ligament space with vital teeth was seen. This finding has not been reported in cases of Williams syndrome earlier. Precautions taken during dental treatment in patients with Williams syndrome are also discussed.<\/jats:p>","DOI":"10.4103\/0976-237x.161908","type":"journal-article","created":{"date-parts":[[2015,7,31]],"date-time":"2015-07-31T03:26:11Z","timestamp":1438313171000},"page":"418-420","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":11,"title":["Dental management of patient with Williams Syndrome - A case report"],"prefix":"10.4103","volume":"6","author":[{"given":"Daniel","family":"Wong","sequence":"first","affiliation":[{"name":"Faculty of Dentistry, SEGi University, Selangor, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Srinivas Sulugodu","family":"Ramachandra","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry, SEGi University, Selangor, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashish Kumar","family":"Singh","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry, SEGi University, Selangor, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20250921","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1161\/01.CIR.24.6.1311","article-title":"Supravalvular aortic stenosis","volume":"24","author":"Williams","year":"1961","journal-title":"Circulation"},{"key":"R2-20250921","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1161\/01.CIR.26.6.1235","article-title":"Supravalvular aortic stenosis in association with mental retardation and a certain facial appearance","volume":"26","author":"Beuren","year":"1962","journal-title":"Circulation"},{"key":"R3-20250921","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1177\/088307380201700406","article-title":"Prevalence estimation of Williams syndrome","volume":"17","author":"Str\u00f8mme","year":"2002","journal-title":"J Child Neurol"},{"key":"R4-20250921","first-page":"22","article-title":"Williams-Beuren syndrome in the Hong Kong Chinese population: Retrospective study","volume":"10","author":"Yau","year":"2004","journal-title":"Hong Kong Med J"},{"key":"R5-20250921","doi-asserted-by":"crossref","first-page":"401","DOI":"10.17796\/jcpd.36.4.c93436771101tm06","article-title":"Orofacial findings and dental management of Williams-Beuren syndrome","volume":"36","author":"Campos-Lara","year":"2012","journal-title":"J Clin Pediatr Dent"},{"key":"R6-20250921","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/j.tripleo.2004.03.019","article-title":"Medical considerations in dental treatment of children with Williams syndrome","volume":"99","author":"Moskovitz","year":"2005","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"R7-20250921","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1002\/ajmg.a.30012","article-title":"Risk of sudden death in the Williams-Beuren syndrome","volume":"127A","author":"Wessel","year":"2004","journal-title":"Am J Med Genet A"},{"key":"R8-20250921","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1212\/01.wnl.0000196643.35395.5f","article-title":"Hyperacusis in Williams syndrome: Characteristics and associated neuroaudiologic abnormalities","volume":"66","author":"Gothelf","year":"2006","journal-title":"Neurology"},{"key":"R9-20250921","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1007\/BF03262626","article-title":"Periodontal conditions in Williams Beuren syndrome: A series of 8 cases","volume":"9","author":"Joseph","year":"2008","journal-title":"Eur Arch Paediatr Dent"},{"key":"R10-20250921","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1080\/00016350310001451","article-title":"Dental characteristics in Williams syndrome: A clinical and radiographic evaluation","volume":"61","author":"Axelsson","year":"2003","journal-title":"Acta Odontol Scand"}],"container-title":["Contemporary Clinical Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/01535384-201506030-00028","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:42:05Z","timestamp":1787067725000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/01535384-201506030-00028"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,7]]},"references-count":10,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015]]}},"URL":"https:\/\/doi.org\/10.4103\/0976-237x.161908","relation":{},"ISSN":["0976-237X","0976-2361"],"issn-type":[{"value":"0976-237X","type":"print"},{"value":"0976-2361","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,7]]}}}