{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T02:04:20Z","timestamp":1788314660447,"version":"build-2803163510"},"reference-count":17,"publisher":"Scientific Scholar","issue":"03","license":[{"start":{"date-parts":[[2019,9,26]],"date-time":"2019-09-26T00:00:00Z","timestamp":1569456000000},"content-version":"vor","delay-in-days":2581,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neurosciences in Rural Practice"],"published-print":{"date-parts":[[2012,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Expansion of cerebral tuberculomas or their new appearance as a manifestation of paradoxical reaction in patients under antituberculous chemotherapy is well documented. Distinguishing paradoxical reaction from disease progression or treatment failure is an important issue in tuberculosis management. Five cases of cerebral tuberculomas are reported here as manifestations of paradoxical reaction in patients with pulmonary and extrapulmonary tuberculosis on antituberculous treatment. Case 1 and 2 had tuberculous meningitis, Case 3 had miliary tuberculosis, Case 4 had miliary tuberculosis and destructive vertebral lesions, and Case 5 had pulmonary tuberculosis. Continuation of antituberculous drugs and addition of steroids led to full recovery of all patients.<\/jats:p>","DOI":"10.4103\/0976-3147.102622","type":"journal-article","created":{"date-parts":[[2012,10,17]],"date-time":"2012-10-17T12:52:56Z","timestamp":1350478376000},"page":"350-354","source":"Crossref","is-referenced-by-count":14,"title":["Cerebral tuberculoma as a manifestation of paradoxical reaction in patients with pulmonary and extrapulmonary tuberculosis"],"prefix":"10.25259","volume":"03","author":[{"given":"Anirban","family":"Das","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Medical College, Kolkata, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sibes Kumar","family":"Das","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Medical College, Kolkata, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhijit","family":"Mandal","sequence":"additional","affiliation":[{"name":"BS Medical College, Bankura, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arup Kumar","family":"Halder","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Columbia \u2013 Asia Hospital, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2019,9,26]]},"reference":[{"key":"key-10.4103\/0976-3147.102622-1","first-page":"7","volume-title":"Treatment of HIV-related tuberculosis in the era of effective antiretroviral therapy","author":"Burman","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"key":"key-10.4103\/0976-3147.102622-2","first-page":"366","volume-title":"Epidemiological, therapeutic and evolutionary profiles in patients with lymph node 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Dis"},{"key":"key-10.4103\/0976-3147.102622-15","first-page":"797","volume-title":"Tuberculosis-associated immune reconstitution inflammatory syndrome and unmasking of tuberculosis by antiretroviral therapy","author":"Meintjes","year":"2009","journal-title":"Clin Chest Med"},{"key":"key-10.4103\/0976-3147.102622-16","first-page":"50","volume-title":"Splenic abscess as a paradoxical response to chemotherapy in tuberculous pleural effusion","author":"Dixit","year":"2010","journal-title":"Ann Thorac Med","ISSN":"https:\/\/id.crossref.org\/issn\/1817-1737","issn-type":"print"},{"key":"key-10.4103\/0976-3147.102622-17","unstructured":"Church P, Judson MA. Paradoxical Reactions and the Immune reconstitution inflammatory syndrome. 5 th ed. Tuberculosis & Nontuberculous My cobacterial Infections.In: Schlossberg D (editor). New Delhi: Tata McGraw-Hill; 2007. p. 400-11."}],"container-title":["Journal of Neurosciences in Rural Practice"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.4103\/0976-3147.102622.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,5]],"date-time":"2023-08-05T04:27:35Z","timestamp":1691209655000},"score":1,"resource":{"primary":{"URL":"https:\/\/ruralneuropractice.com\/cerebral-tuberculoma-as-a-manifestation-of-paradoxical-reaction-in-patients-with-pulmonary-and-extrapulmonary-tuberculosis\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,9]]},"references-count":17,"journal-issue":{"issue":"03","published-online":{"date-parts":[[2019,9,26]]},"published-print":{"date-parts":[[2012,9]]}},"URL":"https:\/\/doi.org\/10.4103\/0976-3147.102622","relation":{},"ISSN":["0976-3147","0976-3155"],"issn-type":[{"value":"0976-3147","type":"print"},{"value":"0976-3155","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,9]]}}}