{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T08:41:35Z","timestamp":1770885695694,"version":"3.50.1"},"reference-count":0,"publisher":"Scientific Scholar","issue":"03","license":[{"start":{"date-parts":[[2019,9,26]],"date-time":"2019-09-26T00:00:00Z","timestamp":1569456000000},"content-version":"vor","delay-in-days":2278,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neurosciences in Rural Practice"],"published-print":{"date-parts":[[2013,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>\n          Aim: To study the profile of children with developmental delay and microcephaly. Materials and Methods: Children attending child development clinic with developmental delay were evaluated as per protocol. Z scores of head circumference were calculated using WHO charts. Clinical, radiological and etiological profile of those with microcephaly and those without was compared. Results: Of the 414 children with developmental delay 231 had microcephaly (z score \u2264 -3). Mean age of children with microcephaly was 35.1 \u00b1 27.9 months (range 4-184), males (72.7%). Comorbidities were epilepsy (42.9%), visual abnormality (26.4%), hearing abnormality (16.9%). Mean DQ was 29.75 + 17.8 in those with microcephaly was significantly lower compared to the rest (P = 0.002). Secondary microcephaly was associated with cerebral palsy in 69.7%. Other causes were congenital infections (4), inborn error of metabolism (3), post-meningoencephalitis (5), malformations (12), and syndromic (13). Neuroimaging was done in 118 (51.1%) cases of which 104 (88.1%) were abnormal. On comparison children with microcephaly had more epilepsy, lower developmental quotient, vision abnormalities findings as compared to normocephalic children with developmental delay (P &amp;003E; 0.05). Conclusion: Microcephaly was associated with lower, DQ, higher comorbidities in children with developmental delay. Spastic CP is commonly associated with microcephaly.<\/jats:p>","DOI":"10.4103\/0976-3147.118781","type":"journal-article","created":{"date-parts":[[2013,9,24]],"date-time":"2013-09-24T13:27:57Z","timestamp":1380029277000},"page":"288-291","source":"Crossref","is-referenced-by-count":20,"title":["Clinical profile of children with developmental delay and microcephaly"],"prefix":"10.25259","volume":"04","author":[{"given":"Anju","family":"Aggarwal","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University College of Medical Sciences and Guru Teg Bahadur Hospital, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hema","family":"Mittal","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University College of Medical Sciences and Guru Teg Bahadur Hospital, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rahul","family":"Patil","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University College of Medical Sciences and Guru Teg Bahadur Hospital, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjib","family":"Debnath","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University College of Medical Sciences and Guru Teg Bahadur Hospital, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anuradha","family":"Rai","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University College of Medical Sciences and Guru Teg Bahadur Hospital, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2019,9,26]]},"container-title":["Journal of Neurosciences in Rural Practice"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.4103\/0976-3147.118781.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,5]],"date-time":"2023-08-05T04:24:00Z","timestamp":1691209440000},"score":1,"resource":{"primary":{"URL":"https:\/\/ruralneuropractice.com\/clinical-profile-of-children-with-developmental-delay-and-microcephaly\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7]]},"references-count":0,"journal-issue":{"issue":"03","published-online":{"date-parts":[[2019,9,26]]},"published-print":{"date-parts":[[2013,7]]}},"URL":"https:\/\/doi.org\/10.4103\/0976-3147.118781","relation":{},"ISSN":["0976-3147","0976-3155"],"issn-type":[{"value":"0976-3147","type":"print"},{"value":"0976-3155","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,7]]}}}