{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T22:22:08Z","timestamp":1778624528295,"version":"3.51.4"},"reference-count":22,"publisher":"Scientific Scholar","issue":"04","license":[{"start":{"date-parts":[[2019,9,25]],"date-time":"2019-09-25T00:00:00Z","timestamp":1569369600000},"content-version":"vor","delay-in-days":1820,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neurosciences in Rural Practice"],"published-print":{"date-parts":[[2014,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>\n          Introduction: Vision loss can be a consequence of numerous disorders of eye and neural pathway conveying visual input to brain. A variety of conditions can affect visual pathway producing neurogenic vision loss. The presentation and course of vision loss depends on the site of involvement and underlying etiology. We conducted this unprecedented study to evaluate the characteristics and outcome of various diseases of the visual pathway. Materials and Methods: In this prospective cohort study, we evaluated 64 patients with neurogenic visual impairment. Ophthalmological causes were excluded in all of them. Their presentation, ophthalmological characteristics and investigation findings were recorded. These patients were followed up till 6 months. Results: Out of 69 patients evaluated, 5 were excluded as they had ophthalmological abnormalities. The remaining 64 cases (113 eyes) were enrolled. 54 cases were due to diseases of anterior visual pathway and rest 10 had cortical vision loss. The etiologic distribution is as follows: Isolated optic neuritis- 12 (19%), multiple sclerosis- 4 (6.3%), neuromyelitis optica- 5 (7.9%), tubercular meningitis- 15 (23.8%), non-arteritic ischemic optic neuropathy, ischemic optic neuropathy complicating cavernous sinus thrombosis, cryptococcal meningitis, malignant infiltration of optic nerve, Crouzon\u2019s syndrome, calvarial thickening and traumatic occipital gliosis- 1 (1.6%) case each, idiopathic intracranial hypertension, pituitary adenoma, acute disseminated encephalomyelitis, posterior reversible leukoencephalopathy- 3 (4.8%) cases each, cortical venous thrombosis 5 (7.9%), subacute scleroing panencephalitis- 4 (6.3%) cases. Conclusions: The diseases of anterior visual pathway were much more common than cortical vision loss. A majority of our patients had severe impairment of vision at presentation.<\/jats:p>","DOI":"10.4103\/0976-3147.139971","type":"journal-article","created":{"date-parts":[[2014,9,3]],"date-time":"2014-09-03T05:36:29Z","timestamp":1409722589000},"page":"340-348","source":"Crossref","is-referenced-by-count":11,"title":["Neurogenic vision loss: Causes and outcome. An experience from a tertiary center in Northern India"],"prefix":"10.25259","volume":"05","author":[{"given":"Rajesh","family":"Verma","sequence":"additional","affiliation":[{"name":"Department of Neurology, King George Medical University, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mani","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Neurology, King George Medical University, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tejendra Sukdeo","family":"Chaudhari","sequence":"additional","affiliation":[{"name":"Department of Neurology, King George Medical University, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2019,9,25]]},"reference":[{"key":"key-10.4103\/0976-3147.139971-1","first-page":"179","volume-title":"Subacute sclerosing panencephalitis.Current status","author":"Dyken","year":"1985","journal-title":"Neurol Clin"},{"key":"key-10.4103\/0976-3147.139971-2","first-page":"81","volume-title":"Optic neuritis: A mechanistic view","author":"Burton","year":"2011","journal-title":"Pathophysiology"},{"key":"key-10.4103\/0976-3147.139971-3","first-page":"1673","volume-title":"Experience of the optic neuritis treatment trial.Optic Neuritis Study Group","author":"The","year":"1991","journal-title":"Arch Ophthalmol"},{"key":"key-10.4103\/0976-3147.139971-4","first-page":"195","volume-title":"Profile of optic neuritis in Chandigarh and surrounding areas","author":"Jain","year":"1981","journal-title":"Indian J Ophthalmol","ISSN":"https:\/\/id.crossref.org\/issn\/0301-4738","issn-type":"print"},{"key":"key-10.4103\/0976-3147.139971-5","first-page":"193","volume-title":"Anterior ischemic optic neuropathy and branch retinal artery occlusion in cavernous sinus thrombosis","author":"Gupta","year":"1990","journal-title":"J Clin Neuroophthalmol"},{"key":"key-10.4103\/0976-3147.139971-6","first-page":"27","volume-title":"Vision impairment in tuberculous meningitis: Predictors and prognosis","author":"Sinha","year":"2010","journal-title":"J Neurol Sci"},{"key":"key-10.4103\/0976-3147.139971-7","first-page":"79","volume-title":"Cerebral venous thrombosis: Update on clinical manifestations, diagnosis and management","author":"Leys","year":"2008","journal-title":"Ann Indian Acad Neurol","ISSN":"https:\/\/id.crossref.org\/issn\/0972-2327","issn-type":"print"},{"key":"key-10.4103\/0976-3147.139971-8","first-page":"24","volume-title":"Posterior leukoencephalopathy syndrome","author":"Garg","year":"2001","journal-title":"Postgrad Med J"},{"key":"key-10.4103\/0976-3147.139971-9","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1007\/978-3-642-11852-4","volume-title":"Management of ischemic optic neuropathies","author":"Hayreh","year":"2011","journal-title":"Indian J Ophthalmol","ISSN":"https:\/\/id.crossref.org\/issn\/0301-4738","issn-type":"print"},{"key":"key-10.4103\/0976-3147.139971-10","unstructured":"World Health Organization. International Statistical Classification of Diseases and Health Related Problems, 10 th Revision-ICD-10. 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