{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,18]],"date-time":"2023-11-18T19:29:32Z","timestamp":1700335772515},"reference-count":6,"publisher":"Scientific Scholar","issue":"04","license":[{"start":{"date-parts":[[2019,9,26]],"date-time":"2019-09-26T00:00:00Z","timestamp":1569456000000},"content-version":"vor","delay-in-days":1273,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neurosciences in Rural Practice"],"published-print":{"date-parts":[[2016,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>\n          Introduction: Magnetic resonance imaging (MRI) is the modality of the first choice for evaluation of vertebral compression\/collapse. Many MRI qualitative features help to differentiate benign from malignant collapse. We conducted this study to look for a quantitative difference in chemical shift values in benign and malignant collapse using dual-echo gradient echo in-phase\/out-phase imaging. Materials and Methods: MRI examinations of a total of 38 patients were retrospectively included in the study who had vertebral compression\/collapse with marrow edema in which final diagnosis was available at the time of imaging\/follow-up. Signal intensity value in the region of abnormal marrow signal and adjacent normal vertebra was measured on in phase\/out phase images. Signal intensity ratio (SIR) was measured by dividing signal intensity value on opposite phase images to that on in phase images. SIR was compared in normal vertebrae and benign and malignant vertebral collapse. Results: There were 21 males and 17 females with mean age of 52.4 years (range 28\u201376 years). Out of total 38 patients, 18 were of benign vertebral collapse and 20 of malignant vertebral collapse. SIR in normal vertebrae was 0.30 \u00b1 0.14, 0.67 \u00b1 0.18 in benign vertebral collapse, and 1.20 \u00b1 0.27 in malignant vertebral collapse with significant difference in SIR of normal vertebrae versus benign collapse (P &lt; 0.01) and in benign collapse versus malignant collapse (P &lt; 0.01). Assuming a cutoff of &lt;0.95 for benign collapse and \u22650.95 for malignant collapse, chemical shift imaging had a sensitivity of 90% and specificity of 94.4%. Conclusion: Chemical shift imaging is a rapid and useful sequence in differentiating benign from malignant vertebral collapse with good specificity and sensitivity.<\/jats:p>","DOI":"10.4103\/0976-3147.188623","type":"journal-article","created":{"date-parts":[[2016,8,18]],"date-time":"2016-08-18T10:40:03Z","timestamp":1471516803000},"page":"489-492","source":"Crossref","is-referenced-by-count":4,"title":["Chemical shift magnetic resonance imaging in differentiation of benign from malignant vertebral collapse in a rural tertiary care hospital in North India"],"prefix":"10.25259","volume":"7","author":[{"given":"Puneet","family":"Mittal","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis, Maharishi Markandeshwar Institute of Medical Sciences and Research, Mullana, Ambala, Haryana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ranjana","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis, Maharishi Markandeshwar Institute of Medical Sciences and Research, Mullana, Ambala, Haryana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amit","family":"Mittal","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis, Maharishi Markandeshwar Institute of Medical Sciences and Research, Mullana, Ambala, Haryana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandeep","family":"Joshi","sequence":"additional","affiliation":[{"name":"Department of Medicine, Maharishi Markandeshwar Institute of Medical Sciences and Research, Mullana, Ambala, Haryana"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2019,9,26]]},"reference":[{"key":"key-10.4103\/0976-3147.188623-1","first-page":"1183","volume-title":"The utility of in-phase\/opposed-phase imaging in differentiating malignancy from acute benign compression fractures of the spine","author":"Erly","year":"2006","journal-title":"AJNR Am J Neuroradiol"},{"key":"key-10.4103\/0976-3147.188623-2","first-page":"779","volume-title":"Quantitative chemical-shift MR imaging cutoff value: Benign versus malignant vertebral compression \u2013 Initial experience","author":"Zidan","year":"2014","journal-title":"Egypt J Radiol Nucl Med"},{"key":"key-10.4103\/0976-3147.188623-3","first-page":"577","volume-title":"Evaluation of vertebral bone marrow fat content by chemical-shift MRI in osteoporosis","author":"Gokalp","year":"2011","journal-title":"Skeletal Radiol"},{"key":"key-10.4103\/0976-3147.188623-4","first-page":"355","volume-title":"Water fraction of lumbar vertebral bone marrow estimated from chemical shift misregistration on MR imaging: Normal variations with age and sex","author":"Ishijima","year":"1996","journal-title":"AJR Am J Roentgenol"},{"key":"key-10.4103\/0976-3147.188623-5","first-page":"1439","volume-title":"In-phase and out-of-phase MR imaging of bone marrow: Prediction of neoplasia based on the detection of coexistent fat and water","author":"Disler","year":"1997","journal-title":"AJR Am J Roentgenol"},{"key":"key-10.4103\/0976-3147.188623-6","first-page":"1020","volume-title":"Vertebral neoplastic compression fractures: Assessment by dual-phase chemical shift imaging","author":"Eito","year":"2004","journal-title":"J Magn Reson Imaging"}],"container-title":["Journal of Neurosciences in Rural Practice"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.4103\/0976-3147.188623.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,3]],"date-time":"2022-10-03T15:17:12Z","timestamp":1664810232000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.4103\/0976-3147.188623"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4]]},"references-count":6,"journal-issue":{"issue":"04","published-online":{"date-parts":[[2019,9,26]]},"published-print":{"date-parts":[[2016,4]]}},"URL":"https:\/\/doi.org\/10.4103\/0976-3147.188623","relation":{},"ISSN":["0976-3147","0976-3155"],"issn-type":[{"value":"0976-3147","type":"print"},{"value":"0976-3155","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,4]]}}}