{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T15:01:22Z","timestamp":1790262082367,"version":"4.1.0"},"reference-count":54,"publisher":"Scientific Scholar","issue":"01","license":[{"start":{"date-parts":[[2019,9,4]],"date-time":"2019-09-04T00:00:00Z","timestamp":1567555200000},"content-version":"vor","delay-in-days":976,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neurosciences in Rural Practice"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>\n          Introduction: The sphenoid sinus is often neglected because of its difficult access. The deep position of the sphenoid sinus hinders early diagnosis of pathologies in that location. Delayed diagnosis can cause serious complications due to proximity to many important structures. Objectives: The aim of this study is to demonstrate different pathologies which can affect the sphenoid sinus and elucidate the findings. Methods: Cases of isolated sphenoid sinus lesions encountered in the neurosurgical setting which had rare pathologies are discussed. Pathologies such as Langerhans cell histiocytosis, solitary plasmacytoma, chordoma, pituitary adenoma, leiomyosarcoma, fungal infection, and mucocele which appeared primarily in sphenoid sinus are discussed along with their imaging features and pathological findings. Conclusion: Multitude of different pathologies can occur in sphenoid sinus. Detailed preoperative imaging is very helpful, but transnasal biopsy and histological study are required often for definitive diagnosis. The possible advantages of early diagnosis before spread of pathology for prognosis cannot be overemphasized.<\/jats:p>","DOI":"10.4103\/0976-3147.193540","type":"journal-article","created":{"date-parts":[[2016,11,8]],"date-time":"2016-11-08T07:30:25Z","timestamp":1478590225000},"page":"107-113","source":"Crossref","is-referenced-by-count":7,"title":["Isolated Sphenoid Sinus Lesions: Experience with a Few Rare Pathologies"],"prefix":"10.25259","volume":"08","author":[{"given":"Nishanth","family":"Sadashiva","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B. N.","family":"Nandeesh","sequence":"additional","affiliation":[{"name":"Department of Neuropathology, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dhaval","family":"Shukla","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dhananjaya","family":"Bhat","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sampath","family":"Somanna","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bhagavatula Indira","family":"Devi","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2019,9,4]]},"reference":[{"key":"key-10.4103\/0976-3147.193540-1","first-page":"323","volume-title":"Isolated sphenoid sinus disease: An analysis of 122 cases","author":"Wang","year":"2002","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"key-10.4103\/0976-3147.193540-2","first-page":"610","volume-title":"The clinical behavior of isolated sphenoid sinusitis","author":"Gilony","year":"2007","journal-title":"Otolaryngol Head Neck Surg"},{"key":"key-10.4103\/0976-3147.193540-3","first-page":"34","volume-title":"Infectious and neoplastic diseases of the sphenoid sinus \u2013 A report of 10 cases","author":"Mra","year":"2002","journal-title":"Rhinology"},{"key":"key-10.4103\/0976-3147.193540-4","first-page":"435","volume-title":"Isolated sphenoid sinus disease","author":"Grillone","year":"2004","journal-title":"Otolaryngol Clin North Am"},{"key":"key-10.4103\/0976-3147.193540-5","first-page":"1590","volume-title":"Isolated sphenoid sinus disease: An analysis of 132 cases","author":"Lawson","year":"1997","journal-title":"Laryngoscope"},{"key":"key-10.4103\/0976-3147.193540-6","first-page":"544","volume-title":"Isolated sphenoid sinus disease: Etiology and management","author":"Friedman","year":"2005","journal-title":"Otolaryngol Head Neck Surg"},{"key":"key-10.4103\/0976-3147.193540-7","first-page":"1108","volume-title":"Langerhans cell histiocytosis of spine: A comparative study of clinical, imaging features, and diagnosis in children, adolescents, and adults","author":"Huang","year":"2013","journal-title":"Spine J"},{"key":"key-10.4103\/0976-3147.193540-8","first-page":"2278","volume-title":"Langerhans cell histiocytosis: Diagnosis, natural history, management, and outcome","author":"Howarth","year":"1999","journal-title":"Cancer"},{"key":"key-10.4103\/0976-3147.193540-9","first-page":"447","volume-title":"Solitary langerhans-cell histiocytosis of the clivus and sphenoid sinus with parasellar and petrous extensions: Case report and a review of literature","author":"Krishna","year":"2004","journal-title":"Surg Neurol"},{"key":"key-10.4103\/0976-3147.193540-10","first-page":"964","volume-title":"Langerhans cell histiocytosis involving the sphenoid sinus and superior orbital fissure","author":"Stromberg","year":"1995","journal-title":"AJNR Am J Neuroradiol"},{"key":"key-10.4103\/0976-3147.193540-11","first-page":"548","volume-title":"Langerhans cell histiocytosis of the sphenoid sinus: A case report","author":"Yu","year":"2010","journal-title":"Turk J Pediatr"},{"key":"key-10.4103\/0976-3147.193540-12","first-page":"251","volume-title":"Cranial nerve palsy in multiple myeloma and solitary plasmacytoma","author":"Kashyap","year":"2010","journal-title":"Asia Pac J Clin Oncol"},{"key":"key-10.4103\/0976-3147.193540-13","first-page":"2226","volume-title":"Solitary intracranial plasmacytoma","author":"Mancardi","year":"1983","journal-title":"Cancer"},{"key":"key-10.4103\/0976-3147.193540-14","first-page":"140","volume-title":"A case of extramedullary plasmacytoma in the sphenoid sinus with unilateral loss of vision","author":"Ozdemir","year":"2013","journal-title":"J Craniomaxillofac Surg"},{"key":"key-10.4103\/0976-3147.193540-15","first-page":"1","volume-title":"Chordoma: Incidence and survival patterns in the United States, 1973-1995","author":"McMaster","year":"2001","journal-title":"Cancer Causes Control"},{"key":"key-10.4103\/0976-3147.193540-16","unstructured":"Intracranial chordoma arising from the sphenoid sinus. 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