{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T16:52:37Z","timestamp":1779900757060,"version":"3.53.1"},"reference-count":15,"publisher":"Scientific Scholar","issue":"01","license":[{"start":{"date-parts":[[2019,9,4]],"date-time":"2019-09-04T00:00:00Z","timestamp":1567555200000},"content-version":"vor","delay-in-days":976,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neurosciences in Rural Practice"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>\n          Introduction: The spectrum of various complications in critically ill Guillain\u2013Barre syndrome (GBS) and its effect on the prognosis is lacking in literature. This study aimed at enumerating the complications in such a cohort and their significance in the prognosis and mortality. Materials and Methods: Retrospective case record analysis of all consecutive mechanically ventilated patients of GBS in neurology Intensive Care Unit (ICU) of a tertiary care institute for 10 years was done. Demographic, laboratory, and treatment details and outcome parameters were recorded. Results: Among the 173 patients were 118 men and 55 women (2.1:1), aged 1\u201384 years. The average number of ICU complications per patient was 6.8 \u00b1 1.8 (median = 7, range = 1\u201312). The most common complication was tracheobronchitis (128). Other pulmonary complications were found in 36 patients. The next was metabolic hyponatremia (115) hypokalemia (67), hypocalcemia (13), stress hyperglycemia (10), hyperkalemia (8), hypernatremia (9). Sepsis (40), UTI (47), dysautonomia (27), hypoalbuminemia (76), anemia (75), seizures (8), paralytic ileus (5), bleeding (4), anoxic encephalopathy (3), organ failures (12), deep vein thrombosis (7), and drug rashes (1) were also noted. The complications, considered significant in causing death, Hughes scale \u2264 3 at discharge, prolonged mechanical ventilation (&gt;21 days) and hospitalization (&gt;36 days) were pneumonia, hyponatremia, hypokalemia, urinary infection, tracheobronchial infections, hypoalbuminemia, sepsis, anemia dysautonomia. Conclusion: Active monitoring and appropriate and early intervention by the clinician will improve the quality of life of these patients and reduce the cost of prolonged mechanical ventilation and ICU stay.<\/jats:p>","DOI":"10.4103\/0976-3147.193542","type":"journal-article","created":{"date-parts":[[2016,11,8]],"date-time":"2016-11-08T07:30:25Z","timestamp":1478590225000},"page":"068-073","source":"Crossref","is-referenced-by-count":13,"title":["Complications in mechanically ventilated patients of Guillain\u2013Barre syndrome and their prognostic value"],"prefix":"10.25259","volume":"08","author":[{"given":"Archana Becket","family":"Netto","sequence":"additional","affiliation":[{"name":"Department of Neurology, Bangalore Medical College and Research Institute, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arun B.","family":"Taly","sequence":"additional","affiliation":[{"name":"Department of Neurology, NIMHANS, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Girish B.","family":"Kulkarni","sequence":"additional","affiliation":[{"name":"Department of Neurology, NIMHANS, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. S.","family":"Uma Maheshwara Rao","sequence":"additional","affiliation":[{"name":"Department of Neuroanesthesia and Neurocritical Care, NIMHANS, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shivaji","family":"Rao","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, NIMHANS, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2019,9,4]]},"reference":[{"key":"key-10.4103\/0976-3147.193542-1","unstructured":"Willison HJ, Jacobs BC, van Doorn PA. Guillain-Barr\u00e9 syndrome. Lancet 2016. pii: S0140-673600339-1."},{"key":"key-10.4103\/0976-3147.193542-2","first-page":"2311","volume-title":"Long-term outcome in patients with Guillain-Barr\u00e9 syndrome requiring mechanical ventilation","author":"Fletcher","year":"2000","journal-title":"Neurology"},{"key":"key-10.4103\/0976-3147.193542-3","first-page":"433","volume-title":"Intensive management and treatment of severe Guillain-Barr\u00e9 syndrome","author":"Hund","year":"1993","journal-title":"Crit Care Med"},{"key":"key-10.4103\/0976-3147.193542-4","first-page":"243","volume-title":"Management and outcome of severe Guillain-Barr\u00e9 syndrome","author":"Ng","year":"1995","journal-title":"QJM"},{"key":"key-10.4103\/0976-3147.193542-5","first-page":"871","volume-title":"Critically ill Guillain Barre' syndrome","author":"Taly","year":"1994","journal-title":"J Assoc Physicians India"},{"key":"key-10.4103\/0976-3147.193542-6","first-page":"17","volume-title":"The morbidity of Guillain-Barr\u00e9 syndrome admitted to the intensive care unit","author":"Henderson","year":"2003","journal-title":"Neurology"},{"key":"key-10.4103\/0976-3147.193542-7","first-page":"262","volume-title":"Mortality in mechanically ventilated patients of Guillain Barr\u00e9 Syndrome","author":"Netto","year":"2011","journal-title":"Ann Indian Acad Neurol","ISSN":"https:\/\/id.crossref.org\/issn\/0972-2327","issn-type":"print"},{"key":"key-10.4103\/0976-3147.193542-8","first-page":"121","volume-title":"The morbidity and outcome of patients with Guillain-Barr\u00e9 syndrome admitted to the intensive care unit","author":"Dhar","year":"2008","journal-title":"J Neurol Sci"},{"key":"key-10.4103\/0976-3147.193542-9","first-page":"S21","volume-title":"Assessment of current diagnostic criteria for Guillain-Barr\u00e9 syndrome","author":"Asbury","year":"1990","journal-title":"Ann Neurol"},{"key":"key-10.4103\/0976-3147.193542-10","first-page":"347","volume-title":"Hyponatremia is a predictor for poor outcome in Guillain-Barr\u00e9 syndrome","author":"Wang","year":"2015","journal-title":"Neurol Res"},{"key":"key-10.4103\/0976-3147.193542-11","first-page":"1403","volume-title":"Mechanical ventilation in patients with Guillain-Barr\u00e9 syndrome","author":"Ali","year":"2006","journal-title":"Respir Care"},{"key":"key-10.4103\/0976-3147.193542-12","first-page":"230","volume-title":"Factors predicting extubation success in patients with Guillain-Barr\u00e9 syndrome","author":"Nguyen","year":"2006","journal-title":"Neurocrit Care"},{"key":"key-10.4103\/0976-3147.193542-13","first-page":"707","volume-title":"Prognosis of patients with Guillain-Barr\u00e9 syndrome requiring mechanical ventilation","author":"Netto","year":"2011","journal-title":"Neurol India","ISSN":"https:\/\/id.crossref.org\/issn\/0028-3886","issn-type":"print"},{"key":"key-10.4103\/0976-3147.193542-14","first-page":"1608","volume-title":"Guillain-Barr\u00e9 syndrome: Incidence and mortality rates in US hospitals","author":"Alshekhlee","year":"2008","journal-title":"Neurology"},{"key":"key-10.4103\/0976-3147.193542-15","first-page":"872","volume-title":"Rehabilitation of Guillain-Barr\u00e9 syndrome","author":"Meythaler","year":"1997","journal-title":"Arch Phys Med Rehabil"}],"container-title":["Journal of Neurosciences in Rural Practice"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.4103\/0976-3147.193542.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,5]],"date-time":"2023-08-05T04:19:00Z","timestamp":1691209140000},"score":1,"resource":{"primary":{"URL":"https:\/\/ruralneuropractice.com\/complications-in-mechanically-ventilated-patients-of-guillain-barre-syndrome-and-their-prognostic-value\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1]]},"references-count":15,"journal-issue":{"issue":"01","published-online":{"date-parts":[[2019,9,4]]},"published-print":{"date-parts":[[2017,1]]}},"URL":"https:\/\/doi.org\/10.4103\/0976-3147.193542","relation":{},"ISSN":["0976-3147","0976-3155"],"issn-type":[{"value":"0976-3147","type":"print"},{"value":"0976-3155","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,1]]}}}