{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T23:48:04Z","timestamp":1791848884453,"version":"4.3.4"},"reference-count":13,"publisher":"Scientific Scholar","issue":"01","license":[{"start":{"date-parts":[[2019,9,26]],"date-time":"2019-09-26T00:00:00Z","timestamp":1569456000000},"content-version":"vor","delay-in-days":2825,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neurosciences in Rural Practice"],"published-print":{"date-parts":[[2012,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>\n          Background: Dengue infections may present with neurological complications. Whether these are due to neuromuscular disease or electrolyte imbalance is unclear. Materials and Methods: Eighty-eight patients of dengue fever required hospitalization during epidemic in year 2010. Twelve of them presented with acute neuromuscular weakness. We enrolled them for study. Diagnosis of dengue infection based on clinical profile of patients, positive serum IgM ELISA, NS1 antigen, and sero-typing. Complete hemogram, kidney and liver functions, serum electrolytes, and creatine phosphokinase (CPK) were tested. In addition, two patients underwent nerve conduction velocity (NCV) test and electromyography. Results: Twelve patients were included in the present study. Their age was between 18 and 34 years. Fever, myalgia, and motor weakness of limbs were most common presenting symptoms. Motor weakness developed on 2 nd to 4 th day of illness in 11 of 12 patients. In one patient, it developed on 10 th day of illness. Ten of 12 showed hypokalemia. One was of Guillain-Barr\u00e9 syndrome and other suffered from myositis; they underwent NCV and electromyography. Serum CPK and SGOT raised in 8 out of 12 patients. CPK of patient of myositis was 5098 IU. All of 12 patients had thrombocytopenia. WBC was in normal range. Dengue virus was isolated in three patients, and it was of serotype 1. CSF was normal in all. Within 24 hours, those with hypokalemia recovered by potassium correction. Conclusions: It was concluded that the dengue virus infection led to acute neuromuscular weakness because of hypokalemia, myositis, and Guillain-Barr\u00e9 syndrome. It was suggested to look for presence of hypokalemia in such patients.<\/jats:p>","DOI":"10.4103\/0976-3147.91928","type":"journal-article","created":{"date-parts":[[2012,1,17]],"date-time":"2012-01-17T09:46:14Z","timestamp":1326793574000},"page":"36-39","source":"Crossref","is-referenced-by-count":31,"title":["Acute neuromuscular weakness associated with dengue infection"],"prefix":"10.25259","volume":"03","author":[{"given":"Harmanjit Singh","family":"Hira","sequence":"additional","affiliation":[{"name":"Departments of Pulmonary Medicine and 1Internal Medicine, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amandeep","family":"Kaur","sequence":"additional","affiliation":[{"name":"Departments of Pulmonary Medicine and 1Internal Medicine, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anuj","family":"Shukla","sequence":"additional","affiliation":[{"name":"Departments of Pulmonary Medicine and 1Internal Medicine, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2019,9,26]]},"reference":[{"key":"key-10.4103\/0976-3147.91928-1","first-page":"357","volume-title":"Acute pure motor quadriplegia: Is it dengue myositis?","author":"Kalita","year":"2005","journal-title":"Electomyogr Clin Neurophysiol"},{"key":"key-10.4103\/0976-3147.91928-2","first-page":"14","volume-title":"Acute dengue virus myositis: A report of seven patients of varying clinical severity including two cases with severe fulminant myositis","author":"Paliwal","year":"2011","journal-title":"J Neurol Sci"},{"key":"key-10.4103\/0976-3147.91928-3","first-page":"144","volume-title":"Bacellar A.Guillain Barre syndrome in the course of dengue: case report","author":"Santos","year":"2004","journal-title":"Arq Neuropsiquiatr"},{"key":"key-10.4103\/0976-3147.91928-4","first-page":"592","volume-title":"Dengue infection causing acute hypokalemic quadriparesis","author":"Jha","year":"2010","journal-title":"Neurol India","ISSN":"https:\/\/id.crossref.org\/issn\/0028-3886","issn-type":"print"},{"key":"key-10.4103\/0976-3147.91928-5","first-page":"2634","volume-title":"Typing of dengue viruses in clinical specimens and mosquitoes by single-tube multiplex reverse transcriptase PCR","author":"Harris","year":"1998","journal-title":"J Clin Microbiol"},{"key":"key-10.4103\/0976-3147.91928-6","first-page":"202","volume-title":"The prevalence of hypokalemia in hospitalized patients with infectious diseases problem at Cipto Mangunkusumo Hospital, Jakarta","author":"Widodo","year":"2006","journal-title":"Acta Med 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