{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:42:31Z","timestamp":1787071351902,"version":"build-2736575974"},"reference-count":24,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:p>Bisphosphonates (BP) are the mainstay of treatment for osteoporosis. Subtrochanteric or diaphyseal fractures have been reported with long term use of BP, which raised world-wide debate on two aspects, i.e., for how long the BP is to be given and potential advantages\/role of BP drug holidays. BP accumulates in bone with some persistent protective effect after therapy is stopped endorses the concept. Theoretically, a drug holiday may be a considerable option to decrease risks of BP, which continuing the protection from fractures but the level of evidence and data supporting the concept of drug holidays is a week. Hence, no specific recommendations are available on BP drug holidays from major available treatment guidelines on postmenopausal osteoporosis. Hence, before it is recommended it requires more robust research in this field.<\/jats:p>","DOI":"10.4103\/0976-7800.141186","type":"journal-article","created":{"date-parts":[[2014,9,19]],"date-time":"2014-09-19T05:33:15Z","timestamp":1411104795000},"page":"111-114","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":5,"title":["Bisphosphonate drug holidays: Can we recommend currently?"],"prefix":"10.4103","volume":"5","author":[{"given":"Vishal R.","family":"Tandon","sequence":"first","affiliation":[{"name":"Department of Pharmacology, Government Medical College, Jammu and Kashmir, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sudhaa","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Government Medical College, Jammu and Kashmir, 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