{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T15:57:33Z","timestamp":1786636653025,"version":"build-2736575974"},"reference-count":51,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Mid-life Health"],"published-print":{"date-parts":[[2012]]},"DOI":"10.4103\/0976-7800.98810","type":"journal-article","created":{"date-parts":[[2012,7,20]],"date-time":"2012-07-20T19:53:11Z","timestamp":1342813991000},"page":"5","source":"Crossref","is-referenced-by-count":13,"title":["Effect of menopause on women\u2032s periodontium"],"prefix":"10.4103","volume":"3","author":[{"given":"Amit","family":"Bhardwaj","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ShaluVerma","family":"Bhardwaj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"key-10.4103\/0976-7800.98810-1","first-page":"671","volume-title":"Influence of sex hormones on the periodontium","author":"Mascarenhas","year":"2003","journal-title":"J Clin Periodontol"},{"key":"key-10.4103\/0976-7800.98810-2","first-page":"27","volume-title":"Sex steroid hormones and cell dynamics in the periodontium","author":"Mariotti","year":"1994","journal-title":"Crit Rev Oral Biol Med"},{"key":"key-10.4103\/0976-7800.98810-3","first-page":"79","volume-title":"Influence of hormonal variation on the periodontium in women","author":"Amar","year":"2000","journal-title":"Periodontol"},{"key":"key-10.4103\/0976-7800.98810-4","first-page":"72","volume-title":"Oral contraceptives and periodontal health","author":"Perry","year":"1981","journal-title":"J West Soc Periodontol Periodontal Abstr"},{"key":"key-10.4103\/0976-7800.98810-5","first-page":"560","volume-title":"Effect of oral contraceptive therapy on gingival inflammation in humans","author":"Kalkwarf","year":"1978","journal-title":"J Periodontol"},{"key":"key-10.4103\/0976-7800.98810-6","first-page":"508","volume-title":"Ovarian hormones and oral health: Pregnancy gingivitis","author":"Zachariasen","year":"1989","journal-title":"Compendium"},{"key":"key-10.4103\/0976-7800.98810-7","first-page":"323","volume-title":"Women\u2032s health issues and their relationship to periodontitis","author":"Krejci","year":"2002","journal-title":"J Am Dent Assoc"},{"key":"key-10.4103\/0976-7800.98810-8","first-page":"138","volume-title":"Effect of endogenous sex hormones on the periodontium- review of literature","author":"Guncu","year":"2005","journal-title":"Aust Dent J"},{"key":"key-10.4103\/0976-7800.98810-9","first-page":"59","volume-title":"Hormonal influences on periodontium","author":"Mealey","year":"2000","journal-title":"Periodontol"},{"key":"key-10.4103\/0976-7800.98810-10","first-page":"1391","volume-title":"Estrogen and extracellular matrix influence human gingival fibroblast proliferation and protein production","author":"Mariotti","year":"2005","journal-title":"J Periodontol"},{"key":"key-10.4103\/0976-7800.98810-11","first-page":"166","volume-title":"Periodontal tissues and sex hormones.Effects of sex hormones on metabolism of fibroblasts derived from periodontal ligament","author":"Nanba","year":"1989","journal-title":"Nippon Shishubyo Gakkai Kaishi"},{"key":"key-10.4103\/0976-7800.98810-12","first-page":"704","volume-title":"Estrogen affects the cellular metabolism of the anterior cruciate ligament.A potential explanation for female athletic injury","author":"Liu","year":"1997","journal-title":"Am J Sports Med"},{"key":"key-10.4103\/0976-7800.98810-13","first-page":"268","volume-title":"Combined effects of estrogen and progesterone on the anterior cruciate ligament","author":"Yu","year":"2001","journal-title":"Clin Orthop"},{"key":"key-10.4103\/0976-7800.98810-14","first-page":"275","volume-title":"Effects of extended systemic and topical folate supplementation on gingivitis of pregnancy","author":"Thomson","year":"1982","journal-title":"J Clin Periodontol"},{"key":"key-10.4103\/0976-7800.98810-15","first-page":"102","volume-title":"Blood flow in the myometrium and endometrium of the uterus","author":"Prill","year":"1961","journal-title":"Am J Obstet Gynecol"},{"key":"key-10.4103\/0976-7800.98810-16","first-page":"185","volume-title":"Changes in microcirculation after local application of sex hormones","author":"Lindhe","year":"1967","journal-title":"J Periodontal Res"},{"key":"key-10.4103\/0976-7800.98810-17","first-page":"259","volume-title":"Changes in vascular permeability after local application of sex hormones","author":"Lindhe","year":"1967","journal-title":"J Periodontal Res"},{"key":"key-10.4103\/0976-7800.98810-18","first-page":"266","volume-title":"Changes in vascular proliferatim after local application of sex hormones","author":"Lindhe","year":"1967","journal-title":"J Periodontal Res"},{"key":"key-10.4103\/0976-7800.98810-19","first-page":"243","volume-title":"Plaque induced periodontal disease in beagle dogs.A 4 year clinical, roentgenorgraphical and histometric study","author":"Lindhe","year":"1975","journal-title":"J Periodontal Res"},{"key":"key-10.4103\/0976-7800.98810-20","first-page":"11","volume-title":"The biological role of the female sex hormone estrogen in the periodontium-studies on human periodontal ligament cells","author":"Jonsson","year":"2007","journal-title":"Swed Dent J Suppl"},{"key":"key-10.4103\/0976-7800.98810-21","first-page":"384","volume-title":"Estradiol prevents and testosteronepromotes Fas-dependent apoptosis in CD4+ Th2 cells by altering Bcl 2 expression","author":"Huber","year":"1999","journal-title":"Lupus"},{"key":"key-10.4103\/0976-7800.98810-22","first-page":"369","volume-title":"Gonodal steroids and immunity","author":"Olsen","year":"1996","journal-title":"Endocr Rev"},{"key":"key-10.4103\/0976-7800.98810-23","first-page":"1558","volume-title":"Alteration in female sex hormones: Their effect on oral tissues and dental treatment","author":"Ferris","year":"1993","journal-title":"Compend Contin Educ Dent"},{"key":"key-10.4103\/0976-7800.98810-24","first-page":"28","volume-title":"Effects of sex hormones on chemotaxis of human peripheral polymorphonuclear leukocytes and monocytes","author":"Miyagi","year":"1992","journal-title":"J Periodontol"},{"key":"key-10.4103\/0976-7800.98810-25","first-page":"3134","volume-title":"Cytokine-induced production of IFN-\u03b22\/IL-6 by freshly explanted human endometrial stromal cells.Modulation by estradiol 17-\u2005\u03b2","author":"Tabibzadeh","year":"1989","journal-title":"J Immunol"},{"key":"key-10.4103\/0976-7800.98810-26","first-page":"279","volume-title":"Modulation by progesterone of interleukin- 6 production by gingival fibroblasts","author":"Lapp","year":"1995","journal-title":"J Periodontol"},{"key":"key-10.4103\/0976-7800.98810-27","first-page":"178","volume-title":"Adrenal and gonodal steroids inhibit Il-6 secretion by human marrow cells","author":"Gordon","year":"2001","journal-title":"Cytokine"},{"key":"key-10.4103\/0976-7800.98810-28","first-page":"1016","volume-title":"Pyrosequencing analysis of the oral microflora of healthy adults","author":"Keijser","year":"2008","journal-title":"J Dent Res"},{"key":"key-10.4103\/0976-7800.98810-29","first-page":"1966","volume-title":"Influence of the menstrual cycle on the oral microbial flora in women: A case-control study including men as control subjects","author":"Fischer","year":"2008","journal-title":"J Periodontol"},{"key":"key-10.4103\/0976-7800.98810-30","first-page":"124","volume-title":"Bacterial steroidogenesis by periodontal pathogens and the effect of bacterial enzymes on steroid conversions by human gingival fibroblasts in culture","author":"Soory","year":"1995","journal-title":"J Periodont Res"},{"key":"key-10.4103\/0976-7800.98810-31","first-page":"309","volume-title":"Targets for steroid hormone mediated actions of periodontal pathogens, cytokines and therapeutic agents: Some implications on tissue turnover in the periodontium","author":"Soory","year":"2000","journal-title":"Curr Drug Targets"},{"key":"key-10.4103\/0976-7800.98810-32","first-page":"255","volume-title":"5 alpha reductase activity in human gingiva and gingival fibroblasts in response to bacterial culture supernatants, using [14C]4-androstenedione as substrate","author":"Soory","year":"1997","journal-title":"Arch Oral Biol"},{"key":"key-10.4103\/0976-7800.98810-33","first-page":"197","volume-title":"Changes in paraurethral connective tissue at menopause is counteracted by estrogen","author":"Falconer","year":"1996","journal-title":"Maturitas"},{"key":"key-10.4103\/0976-7800.98810-34","first-page":"1014","volume-title":"The effect of 17 beta -estradiol on collagen and noncollagenous protein synthesis in the uterus and some periodontal tissues","author":"Dyer","year":"1980","journal-title":"Endocrinology"},{"key":"key-10.4103\/0976-7800.98810-35","first-page":"21","volume-title":"The effect of elevated ovarian hormones on periodontal health: Oral contraceptives and pregnancy","author":"Zachariasen","year":"1993","journal-title":"Women Health"},{"key":"key-10.4103\/0976-7800.98810-36","first-page":"132","volume-title":"Periodontal aspects in menopausal women undergoing hormone replacement therapy","author":"Lopez-Marcos","year":"2005","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"key-10.4103\/0976-7800.98810-37","doi-asserted-by":"crossref","unstructured":"Taichman LS, Sohn W, Kolenic G, Sowers M. Depot Medroxyprogesterone Acetate Use and Periodontal Health in United States Women Ages 15-44. J Periodontal 2012.","DOI":"10.1902\/jop.2012.110534"},{"key":"key-10.4103\/0976-7800.98810-38","first-page":"536","volume-title":"Postmenopausal estrogen replacement and tooth retention","author":"Krallb","year":"1997","journal-title":"Am J Med"},{"key":"key-10.4103\/0976-7800.98810-39","first-page":"957","volume-title":"Periodontal status of women taking postmenopausal estrogen supplementation","author":"Norderyd","year":"1993","journal-title":"J Periodontol"},{"key":"key-10.4103\/0976-7800.98810-40","first-page":"1584","volume-title":"Oral manifestations of menopause","author":"Zachariasen","year":"1993","journal-title":"Compendium"},{"key":"key-10.4103\/0976-7800.98810-41","first-page":"S65","volume-title":"Estrogen and bone metabolism","author":"Harkonen","year":"1996","journal-title":"Maturitas"},{"key":"key-10.4103\/0976-7800.98810-42","first-page":"1745","volume-title":"Estrogen regulates expression of osteoprotegerin and RANKL in human periodontal ligament cells through estrogen receptor beta","author":"Liang","year":"2008","journal-title":"J Periodontol"},{"key":"key-10.4103\/0976-7800.98810-43","doi-asserted-by":"crossref","unstructured":"Weitzmann N, Pacifici R. Estrogen regulation of immune cell bone interactions. New York: Academy of Sciences; 2006.","DOI":"10.1196\/annals.1346.030"},{"key":"key-10.4103\/0976-7800.98810-44","first-page":"12","volume-title":"Periodontal host modulation with antiproteinase, anti-inflammatory and bone-sparing agents.A syatematic review","author":"Reddy","year":"2003","journal-title":"Ann Periodontol"},{"key":"key-10.4103\/0976-7800.98810-45","first-page":"813","volume-title":"Bisphosphonates and periodontics: Potential applications for regulation of bone mass in the periodontium and other therapeutic\/ diagnostic uses","author":"Tenenbaum","year":"2002","journal-title":"J Periodontol"},{"key":"key-10.4103\/0976-7800.98810-46","first-page":"1113","volume-title":"Bisphosphonate therapy improves the outcome of conventional periodontal treatment: Results of a 12-month, randomized, placebo-controlled study","author":"Lane","year":"2005","journal-title":"J Periodontol"},{"key":"key-10.4103\/0976-7800.98810-47","first-page":"1579","volume-title":"Effect of alendronate on periodontal disease in postmenopausal women: A randomized placebo-controlled trial","author":"Rocha","year":"2004","journal-title":"J Periodontol"},{"key":"key-10.4103\/0976-7800.98810-48","first-page":"685","volume-title":"Periodontal assessment of postmenopausal women receiving risedronate","author":"Palomo","year":"2005","journal-title":"Menopause"},{"key":"key-10.4103\/0976-7800.98810-49","doi-asserted-by":"crossref","unstructured":"Palomo L, James L, Nabil FB. Skeletal bone diseases impact the periodontium: A review of bisphosphonate therapy. Expert Opin Pharmacother 2007;8;309-15.","DOI":"10.1517\/14656566.8.3.309"},{"key":"key-10.4103\/0976-7800.98810-50","first-page":"467","volume-title":"How menopause affects oral health, and what we can do about it","author":"Buencamino","year":"2009","journal-title":"Cleve Clin J Med"},{"key":"key-10.4103\/0976-7800.98810-51","first-page":"629","volume-title":"Menopause, vitamin-D and oral health","author":"Mascitelli","year":"2009","journal-title":"Cleve Clin J Med"}],"container-title":["Journal of Mid-life Health"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T14:59:34Z","timestamp":1786633174000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/0976-7800.98810"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":51,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012]]}},"alternative-id":["98810"],"URL":"https:\/\/doi.org\/10.4103\/0976-7800.98810","relation":{},"ISSN":["0976-7800"],"issn-type":[{"value":"0976-7800","type":"print"}],"subject":[],"published":{"date-parts":[[2012]]}}}