{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:54:37Z","timestamp":1786650877026,"version":"build-2736575974"},"reference-count":28,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Asian J Androl"],"published-print":{"date-parts":[[2014]]},"DOI":"10.4103\/1008-682x.123670","type":"journal-article","created":{"date-parts":[[2014,4,30]],"date-time":"2014-04-30T07:53:01Z","timestamp":1398844381000},"page":"472","source":"Crossref","is-referenced-by-count":9,"title":["Avanafil for male erectile dysfunction: a systematic review and meta-analysis"],"prefix":"10.4103","volume":"16","author":[{"given":"Yong","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan-Shan","family":"Cui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huan-Tao","family":"Zong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui-Lei","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"key-10.4103\/1008-682X.123670-1","first-page":"1397","volume-title":"Oral sildenafil in the treatment of erectile dysfunction.Sildenafil Study Group","author":"Goldstein","year":"1998","journal-title":"N Engl J Med"},{"key":"key-10.4103\/1008-682X.123670-2","first-page":"460","volume-title":"Incidence of erectile dysfunction in men 40 to 69 years old: longitudinal results from the Massachusetts Male Aging Study","author":"Johannes","year":"2000","journal-title":"J Urol"},{"key":"key-10.4103\/1008-682X.123670-3","first-page":"151","volume-title":"Prevalence and risk factors for erectile dysfunction in the US","author":"Selvin","year":"2007","journal-title":"Am J Med"},{"key":"key-10.4103\/1008-682X.123670-4","first-page":"19","volume-title":"The underlying pathophysiology and causes of erectile dysfunction","author":"Wyllie","year":"2005","journal-title":"Clin Cornerstone"},{"key":"key-10.4103\/1008-682X.123670-5","first-page":"795\u2212801","volume-title":"Assessment of the relational factor in male patients consulting for sexual dysfunction: the concept of couple sexual dysfunction","author":"Corona","year":"2006","journal-title":"J Androl"},{"key":"key-10.4103\/1008-682X.123670-6","first-page":"1598","volume-title":"Definitions\/epidemiology\/risk factors for sexual dysfunction","author":"Lewis","year":"2010","journal-title":"J Sex Med"},{"key":"key-10.4103\/1008-682X.123670-7","first-page":"3418","volume-title":"Phosphodiesterase type 5 (PDE5) inhibitors in erectile dysfunction: the proper drug for the proper patient","author":"Corona","year":"2011","journal-title":"J Sex Med"},{"key":"key-10.4103\/1008-682X.123670-8","first-page":"230","volume-title":"Chapter 1: the management of erectile dysfunction: an AUA update","author":"Montague","year":"2005","journal-title":"J Urol"},{"key":"key-10.4103\/1008-682X.123670-9","first-page":"806","volume-title":"EAU Guidelines on erectile dysfunction: an update","author":"Wespes","year":"2006","journal-title":"Eur Urol"},{"key":"key-10.4103\/1008-682X.123670-10","first-page":"243","volume-title":"After two years, did Viagra live up to its expectations?","author":"Madduri","year":"2001","journal-title":"Mo Med"},{"key":"key-10.4103\/1008-682X.123670-11","first-page":"603\u22129","volume-title":"An update on new oral PDE5 inhibitors for the treatment of erectile dysfunction","author":"Palit","year":"2010","journal-title":"Nat Rev Urol"},{"key":"key-10.4103\/1008-682X.123670-12","first-page":"668","volume-title":"Avanafil, a potent and highly selective phosphodiesterase-5 inhibitor for erectile dysfunction","author":"Kotera","year":"2012","journal-title":"J Urol"},{"key":"key-10.4103\/1008-682X.123670-13","first-page":"2122\u22129","volume-title":"Selectivity of avanafil, a PDE5 inhibitor for the treatment of erectile dysfunction: implications for clinical safety and improved tolerability","author":"Wang","year":"2012","journal-title":"J Sex Med"},{"key":"key-10.4103\/1008-682X.123670-14","first-page":"S466","volume-title":"Pharmacokinetics of avanafil, a novel, rapidly absorbed, selective PDE5 inhibitor for the treatment of mild to severe erectile dysfunction","author":"Allison","year":"2011","journal-title":"J Sex Med"},{"key":"key-10.4103\/1008-682X.123670-15","unstructured":"STENDRA (avanafil) tablets prescribing information. Mountain View, California: VIVUS, Inc 2012."},{"key":"key-10.4103\/1008-682X.123670-16","unstructured":"Jadad AR. Randomised controlled trials. London: BMJ Publishing Group1998."},{"key":"key-10.4103\/1008-682X.123670-17","unstructured":"Higgins JPT, Green S, editors. Cochrane handbook for systematic reviews of interventions, v. 5.1 [updated March 2011]. Cochrane Collaboration Web site. Available from: http:\/\/www.cochrane-handbook.org."},{"key":"key-10.4103\/1008-682X.123670-18","first-page":"177","volume-title":"Meta-analysis in clinical trials","author":"DerSimonian","year":"1986","journal-title":"Control Clin Trials"},{"key":"key-10.4103\/1008-682X.123670-19","first-page":"1801\u22126","volume-title":"Efficacy and safety of avanafil for treating erectile dysfunction: results of a multicentre, randomized, double-blind, placebo-controlled trial","author":"Zhao","year":"2012","journal-title":"BJU Int"},{"key":"key-10.4103\/1008-682X.123670-20","first-page":"1122\u221233","volume-title":"A randomized, double-blind, placebo-controlled evaluation of the safety and efficacy of avanafil in subjects with erectile dysfunction","author":"Goldstein","year":"2012","journal-title":"J Sex Med"},{"key":"key-10.4103\/1008-682X.123670-21","first-page":"843\u221252","volume-title":"Avanafil for the treatment of erectile dysfunction: a multicenter, randomized, double-blind study in men with diabetes mellitus","author":"Goldstein","year":"2012","journal-title":"Mayo Clin Proc"},{"key":"key-10.4103\/1008-682X.123670-22","first-page":"2229","volume-title":"A Phase 3, placebo controlled study of the safety and efficacy of avanafil for the treatment of erectile dysfunction after nerve sparing radical prostatectomy","author":"Mulhall","year":"2012","journal-title":"J Urol"},{"key":"key-10.4103\/1008-682X.123670-23","first-page":"1427\u221237","volume-title":"Avanafil, a new rapid-onset phosphodiesterase 5 inhibitor for the treatment of erectile dysfunction","author":"Limin","year":"2010","journal-title":"Expert Opin Investig Drugs"},{"key":"key-10.4103\/1008-682X.123670-24","first-page":"435\u221243","volume-title":"Future prospects in the treatment of erectile dysfunction: focus on avanafil","author":"Alwaal","year":"2011","journal-title":"Drug Des Devel Ther"},{"key":"key-10.4103\/1008-682X.123670-25","first-page":"137\u221247","volume-title":"A phase II, single-blind, randomized, crossover evaluation of the safety and efficacy of avanafil using visual sexual stimulation in patients with mild to moderate erectile dysfunction","author":"Hellstrom","year":"2013","journal-title":"BJU Int"},{"key":"key-10.4103\/1008-682X.123670-26","first-page":"650","volume-title":"Oral phosphodiesterase-5 inhibitors and hormonal treatments for erectile dysfunction: a systematic review and meta-analysis","author":"Tsertsvadze","year":"2009","journal-title":"Ann Intern Med"},{"key":"key-10.4103\/1008-682X.123670-27","first-page":"67\u221290","volume-title":"A 4-year update on the safety of sildenafil citrate (Viagra)","author":"Padmanathan","year":"2002","journal-title":"Urology"},{"key":"key-10.4103\/1008-682X.123670-28","first-page":"1621","volume-title":"A comparative review of the options for treatment of erectile dysfunction: which treatment for which patient?","author":"Hatzimouratidis","year":"2005","journal-title":"Drugs"}],"container-title":["Asian Journal of Andrology"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:23:56Z","timestamp":1786649036000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/1008-682X.123670"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":28,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014]]}},"alternative-id":["123670"],"URL":"https:\/\/doi.org\/10.4103\/1008-682x.123670","relation":{},"ISSN":["1008-682X"],"issn-type":[{"value":"1008-682X","type":"print"}],"subject":[],"published":{"date-parts":[[2014]]}}}