{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T20:26:51Z","timestamp":1786652811698,"version":"build-2736575974"},"reference-count":32,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Niger J Clin Pract"],"published-print":{"date-parts":[[2014]]},"DOI":"10.4103\/1119-3077.141417","type":"journal-article","created":{"date-parts":[[2014,9,22]],"date-time":"2014-09-22T05:23:10Z","timestamp":1411363390000},"page":"559","source":"Crossref","is-referenced-by-count":8,"title":["Experimental investigation of relationship between trauma and bisphosphonate-related osteonecrosis"],"prefix":"10.4103","volume":"17","author":[{"given":"KS","family":"Aga\u00e7ayak","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H","family":"Yuksel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Atilgan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Koparal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MC","family":"U\u00e7an","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"\u00d6zg\u00f6z","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F","family":"Yaman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y","family":"Atalay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I","family":"Acikan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"key-10.4103\/1119-3077.141417-1","first-page":"1405","volume-title":"Effect of zoledronate on oral wound healing in rats","author":"Yamashita","year":"2011","journal-title":"Clin Cancer Res"},{"key":"key-10.4103\/1119-3077.141417-2","first-page":"2803","volume-title":"Zoledronic acid repolarizes tumour-associated macrophages and inhibits mammary carcinogenesis by targeting the mevalonate pathway","author":"Coscia","year":"2010","journal-title":"J Cell Mol Med"},{"key":"key-10.4103\/1119-3077.141417-3","first-page":"17","volume-title":"Increased numbers of nonattached osteoclasts after long-term zoledronic acid therapy in mice","author":"Kuroshima","year":"2012","journal-title":"Endocrinology"},{"key":"key-10.4103\/1119-3077.141417-4","first-page":"491","volume-title":"Bisphosphonate effects on the behaviour of oral epithelial cells and oral fibroblasts","author":"Ravosa","year":"2011","journal-title":"Arch Oral Biol"},{"key":"key-10.4103\/1119-3077.141417-5","first-page":"906","volume-title":"Zoledronic acid induces S-phase arrest via a DNA damage response in normal human oral keratinocytes","author":"Ohnuki","year":"2012","journal-title":"Arch Oral Biol"},{"key":"key-10.4103\/1119-3077.141417-6","first-page":"183","volume-title":"Physiological and pathological role of the ubiquitin-proteasome system in the vascular smooth muscle cell","author":"Demasi","year":"2012","journal-title":"Cardiovasc Res"},{"key":"key-10.4103\/1119-3077.141417-7","first-page":"237","volume-title":"A role for C-terminal cross-linking telopeptide level to predict the development of bisphosphonate-related osteonecrosis of the jaws following oral surgery?","author":"O\u2032Connell","year":"2012","journal-title":"Ir J Med Sci"},{"key":"key-10.4103\/1119-3077.141417-8","first-page":"2241","volume-title":"Serologic bone markers for predicting development of osteonecrosis of the jaw in patients receiving bisphosphonates","author":"Lazarovici","year":"2010","journal-title":"J Oral Maxillofac Surg"},{"key":"key-10.4103\/1119-3077.141417-9","first-page":"1167","volume-title":"Clinical investigation of C-terminal cross-linking telopeptide test in prevention and management of bisphosphonate-associated osteonecrosis of the jaws","author":"Kunchur","year":"2009","journal-title":"J Oral Maxillofac Surg"},{"key":"key-10.4103\/1119-3077.141417-10","first-page":"1871","volume-title":"Periodontal disease and bisphosphonates induce osteonecrosis of the jaws in the rat","author":"Aghaloo","year":"2011","journal-title":"J Bone Miner Res"},{"key":"key-10.4103\/1119-3077.141417-11","first-page":"1337","volume-title":"Increased prevalence of bisphosphonate-related osteonecrosis of the jaw with vitamin D deficiency in rats","author":"Hokugo","year":"2010","journal-title":"J Bone Miner Res"},{"key":"key-10.4103\/1119-3077.141417-12","first-page":"1567","volume-title":"Bisphosphonate-induced exposed bone (osteonecrosis\/osteopetrosis) of the jaws: Risk factors, recognition, prevention, and treatment","author":"Marx","year":"2005","journal-title":"J Oral Maxillofac Surg"},{"key":"key-10.4103\/1119-3077.141417-13","first-page":"697","volume-title":"An experimental study of bisphosphonate-induced jaws osteonecrosis in Sprague-Dawley rats","author":"L\u00f3pez-Jornet","year":"2010","journal-title":"J Oral Pathol Med"},{"key":"key-10.4103\/1119-3077.141417-14","first-page":"390","volume-title":"A novel animal model to study non-spontaneous bisphosphonates osteonecrosis of jaw","author":"Biasotto","year":"2010","journal-title":"J Oral Pathol Med"},{"key":"key-10.4103\/1119-3077.141417-15","first-page":"7","volume-title":"Oral bisphosphonate-related osteonecrosis of the jaws in rheumatoid arthritis patients: A critical discussion and two case reports","author":"Conte-Neto","year":"2011","journal-title":"Head Face Med"},{"key":"key-10.4103\/1119-3077.141417-16","first-page":"119","volume-title":"American Association of Oral and Maxillofacial Surgeons position paper on bisphosphonate-related osteonecrosis of the jaw-2009 update","author":"Ruggiero","year":"2009","journal-title":"Aust Endod J"},{"key":"key-10.4103\/1119-3077.141417-17","first-page":"1904","volume-title":"Bisphosphonate-related osteonecrosis of the jaw: Clinical features, risk factors, management, and treatment outcomes of 26 patients","author":"Thumbigere-Math","year":"2009","journal-title":"J Oral Maxillofac Surg"},{"key":"key-10.4103\/1119-3077.141417-18","first-page":"88","volume-title":"Dental panoramic radiographic evaluation in bisphosphonate-associated osteonecrosis of the jaws","author":"Treister","year":"2009","journal-title":"Oral Dis"},{"key":"key-10.4103\/1119-3077.141417-19","first-page":"369","volume-title":"American Association of Oral and Maxillofacial Surgeons position paper on bisphosphonate-related osteonecrosis of the jaws","author":"Advisory","year":"2007","journal-title":"J Oral Maxillofac Surg"},{"key":"key-10.4103\/1119-3077.141417-20","first-page":"367","volume-title":"Extraction site healing in rats.A radiologic densitometric study","author":"Bodner","year":"1993","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"key-10.4103\/1119-3077.141417-21","first-page":"153","volume-title":"Wound healing following tooth extraction.Histochemical study in rats","author":"Okamoto","year":"1973","journal-title":"Rev Fac Odontol Aracatuba"},{"key":"key-10.4103\/1119-3077.141417-22","first-page":"674","volume-title":"Effects of alendronate on bone healing after tooth extraction in rats","author":"Aguirre","year":"2010","journal-title":"Oral Dis"},{"key":"key-10.4103\/1119-3077.141417-23","unstructured":"Marx R. Oral and Intravenous Bisphosphonate-Induced Osteonecrosis of the Jaws. Chicago: Quintessence Publishing Co.; 2007."},{"key":"key-10.4103\/1119-3077.141417-24","first-page":"4","volume-title":"Chemical and biological prerequisites for novel bisphosphonate molecules: Results of comparative preclinical studies","author":"Green","year":"2001","journal-title":"Semin Oncol"},{"key":"key-10.4103\/1119-3077.141417-25","first-page":"657","volume-title":"Osteoclasts degrade endosteal components and promote mobilization of hematopoietic progenitor cells","author":"Kollet","year":"2006","journal-title":"Nat Med"},{"key":"key-10.4103\/1119-3077.141417-26","first-page":"99","volume-title":"Osteonecrosis of the jaw and bisphosphonates","author":"Durie","year":"2005","journal-title":"N Engl J Med"},{"key":"key-10.4103\/1119-3077.141417-27","first-page":"826","volume-title":"Frequency and risk factors associated with osteonecrosis of the jaw in cancer patients treated with intravenous bisphosphonates","author":"Hoff","year":"2008","journal-title":"J Bone Miner Res"},{"key":"key-10.4103\/1119-3077.141417-28","first-page":"1430","volume-title":"Bisphosphonate effects on alveolar bone during rat molar drifting","author":"Hardt","year":"1988","journal-title":"J Dent Res"},{"key":"key-10.4103\/1119-3077.141417-29","first-page":"2397","volume-title":"Oral bisphosphonate-induced osteonecrosis: Risk factors, prediction of risk using serum CTX testing, prevention, and treatment","author":"Marx","year":"2007","journal-title":"J Oral Maxillofac Surg"},{"key":"key-10.4103\/1119-3077.141417-30","first-page":"467","volume-title":"Clinical use of biochemical markers of bone remodeling: Current status and future directions","author":"Looker","year":"2000","journal-title":"Osteoporos Int"},{"key":"key-10.4103\/1119-3077.141417-31","first-page":"65","volume-title":"Collagen turnover in bone diseases","author":"Robins","year":"2003","journal-title":"Curr Opin Clin Nutr Metab Care"},{"key":"key-10.4103\/1119-3077.141417-32","first-page":"59","volume-title":"Bone turnover markers as predictors of skeletal complications in prostate cancer, lung cancer, and other solid tumors","author":"Brown","year":"2005","journal-title":"J Natl Cancer Inst"}],"container-title":["Nigerian Journal of Clinical Practice"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:26:45Z","timestamp":1786649205000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/1119-3077.141417"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":32,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2014]]}},"alternative-id":["141417"],"URL":"https:\/\/doi.org\/10.4103\/1119-3077.141417","relation":{},"ISSN":["1119-3077"],"issn-type":[{"value":"1119-3077","type":"print"}],"subject":[],"published":{"date-parts":[[2014]]}}}