{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T20:34:25Z","timestamp":1786653265582,"version":"build-2736575974"},"reference-count":16,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Niger J Clin Pract"],"published-print":{"date-parts":[[2015]]},"DOI":"10.4103\/1119-3077.151806","type":"journal-article","created":{"date-parts":[[2015,2,19]],"date-time":"2015-02-19T05:25:30Z","timestamp":1424323530000},"page":"432","source":"Crossref","is-referenced-by-count":6,"title":["Progressive myelopathy, a consequence of intra-thecal chemotherapy: Case report and review of the literature"],"prefix":"10.4103","volume":"18","author":[{"given":"BF","family":"Chukwu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"IF","family":"Ukekwe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"OU","family":"Ezenwosu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"CO","family":"Ani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"AN","family":"Ikefuna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"IJ","family":"Emodi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"key-10.4103\/1119-3077.151806-1","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1007\/s00277-008-0645-y","article-title":"Intrathecal chemotherapy for hematologic malignancies: Drugs and toxicities","author":"Kwong","year":"2009","journal-title":"Ann Hematol"},{"key":"key-10.4103\/1119-3077.151806-2","doi-asserted-by":"crossref","first-page":"2003","DOI":"10.1002\/1097-0142(19841101)54:9<2003::AID-CNCR2820540936>3.0.CO;2-R","article-title":"Transient neurologic dysfunction following moderate-dose methotrexate for undifferentiated lymphoma","author":"Martino","year":"1984","journal-title":"Cancer"},{"key":"key-10.4103\/1119-3077.151806-3","first-page":"1107","article-title":"Paraplegia following intrathecal chemotherapy","author":"Beretta","year":"1996","journal-title":"Schweiz Med Wochenschr"},{"key":"key-10.4103\/1119-3077.151806-4","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1097\/01.mph.0000162527.85024.e9","article-title":"Myelopathy due to intrathecal chemotherapy: Report of six cases","author":"Bay","year":"2005","journal-title":"J Pediatr Hematol Oncol"},{"key":"key-10.4103\/1119-3077.151806-5","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/0387-7604(94)90079-5","article-title":"Acute ascending myelitis and encephalopathy after intrathecal cytosine arabinoside and methotrexate in an adolescent boy with acute lymphoblastic leukemia","author":"Oz\u00f6n","year":"1994","journal-title":"Brain Dev"},{"key":"key-10.4103\/1119-3077.151806-6","unstructured":"FMOH. National Guideline on Cancer Chemotherapy. 2009. pg. 7-9."},{"key":"key-10.4103\/1119-3077.151806-7","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1002\/(SICI)1097-0142(19990115)85:2<511::AID-CNCR33>3.0.CO;2-H","article-title":"Intraventricular concentration times time (C x T) methotrexate and cytarabine for patients with recurrent meningeal leukemia and lymphoma","author":"Moser","year":"1999","journal-title":"Cancer"},{"key":"key-10.4103\/1119-3077.151806-8","unstructured":"David GT, Bleyer A. The leukemias. In Behrman RE, Kliegman RM, Jenson HB, Stanton BF, editors. Nelson Textbook of Pediatrics. Philadelphia: Saunders Elsevier; 2007. p. 459.1"},{"key":"key-10.4103\/1119-3077.151806-9","first-page":"25","article-title":"Central nervous system toxicity of chemotherapy","author":"Schlegel","year":"2011","journal-title":"Eur Assoc Neurooncol Mag"},{"key":"key-10.4103\/1119-3077.151806-10","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1002\/1097-0142(19930101)71:1<117::AID-CNCR2820710119>3.0.CO;2-K","article-title":"Acute neurotoxicity after intrathecal cytosine arabinoside in two adolescents with acute lymphoblastic leukemia of B-cell type","author":"Resar","year":"1993","journal-title":"Cancer"},{"key":"key-10.4103\/1119-3077.151806-11","doi-asserted-by":"crossref","first-page":"3037","DOI":"10.1002\/1097-0142(19940615)73:12<3037::AID-CNCR2820731223>3.0.CO;2-6","article-title":"Myelopathy after intrathecal chemotherapy.A case report with unique magnetic resonance imaging changes","author":"McLean","year":"1994","journal-title":"Cancer"},{"key":"key-10.4103\/1119-3077.151806-12","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1111\/j.1552-6569.2007.00094.x","article-title":"MR findings of intrathecal chemotherapy-related myelopathy in two cases: Mimicker of subacute combined degeneration","author":"Lu","year":"2007","journal-title":"J Neuroimaging"},{"key":"key-10.4103\/1119-3077.151806-13","first-page":"192","article-title":"Acute fatal myeloencephalopathy after combined intrathecal chemotherapy in a child with acute lymphoblastic leukemia","author":"von","year":"1991","journal-title":"Med Pediatr Oncol"},{"key":"key-10.4103\/1119-3077.151806-14","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1007\/s11060-009-0028-9","article-title":"Methotrexate-induced myelopathy responsive to substitution of multiple folate metabolites","author":"Ackermann","year":"2010","journal-title":"J Neurooncol"},{"key":"key-10.4103\/1119-3077.151806-15","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1111\/j.1651-2227.1992.tb12244.x","article-title":"Cerebrospinal fluid exchange after intrathecal methotrexate overdose.A report of two cases","author":"Jakobson","year":"1992","journal-title":"Acta Paediatr"},{"key":"key-10.4103\/1119-3077.151806-16","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.neuro.2003.10.004","article-title":"Emergency treatment of life-threatening intrathecal methotrexate overdose","author":"Finkelstein","year":"2004","journal-title":"Neurotoxicology"}],"container-title":["Nigerian Journal of Clinical Practice"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:34:20Z","timestamp":1786649660000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/1119-3077.151806"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":16,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015]]}},"alternative-id":["151806"],"URL":"https:\/\/doi.org\/10.4103\/1119-3077.151806","relation":{},"ISSN":["1119-3077"],"issn-type":[{"value":"1119-3077","type":"print"}],"subject":[],"published":{"date-parts":[[2015]]}}}