{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T22:34:10Z","timestamp":1767652450211},"reference-count":28,"publisher":"Georg Thieme Verlag KG","issue":"04","license":[{"start":{"date-parts":[[2019,9,24]],"date-time":"2019-09-24T00:00:00Z","timestamp":1569283200000},"content-version":"vor","delay-in-days":1088,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Dent"],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>\n          Objective: The objective of the study was to evaluate clinically and radiographically the efficacy of platelet-rich fibrin (PRF) versus \u03b2-tri-calcium phosphate (\u03b2-TCP) in the treatment of Grade II mandibular furcation defects. Materials and Methods: Forty-five Grade II furcation defect in mandibular molars which were assigned to open flap debridement (OFD) with PRF Group I (n = 15), to OFD with \u03b2-TCP Group II (n = 15), and to OFD alone Group III (n = 15) were analyzed for clinical parameters (probing pocket depth [PPD], vertical clinical attachment level [VCAL], horizontal clinical attachment level [HCAL], gingival recession, relative vertical height of furcation [r-VHF], and relative horizontal depth of furcation [r-HDF]) and radiographical parameters (horizontal depth of furcation [H-DOF], vertical height of furcation [V-HOF]) using cone-beam computed tomography (CBCT) at 6 months interval. Results: For clinical parameters, reduction in PPD and gain in VCAL and HCAL were higher in Group II as compared to Group I. Change in r-VHF and r-HDF was greater in Group II as compared to Group I. Mean percentage clinical vertical defect fill was higher in Group II as compared to Group I (58.52% \u00b1 11.68% vs. 53.24% \u00b1 13.22%, respectively). On CBCT, mean change at 6 months for all parameters showed nonsignificant difference between the two experimental groups. Mean change in V-HOF was higher in Group I as compared to Group II, but mean change in H-DOF and furcation width was more in Group II as compared to Group I. Conclusion: For both experimental and control groups, there was statistically significant improvement at 6 months follow-up from baseline values.<\/jats:p>","DOI":"10.4103\/1305-7456.195160","type":"journal-article","created":{"date-parts":[[2016,12,5]],"date-time":"2016-12-05T03:49:08Z","timestamp":1480909748000},"page":"496-506","source":"Crossref","is-referenced-by-count":15,"title":["Comparative evaluation of platelet-rich fibrin versus beta-tri-calcium phosphate in the treatment of Grade II mandibular furcation defects using cone-beam computed tomography"],"prefix":"10.1055","volume":"10","author":[{"given":"Zeba Rahman","family":"Siddiqui","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Saraswati Dental College and Hospital, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajesh","family":"Jhingran","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Saraswati Dental College and Hospital, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vivek Kumar","family":"Bains","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Saraswati Dental College and Hospital, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruchi","family":"Srivastava","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Saraswati Dental College and Hospital, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rohit","family":"Madan","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Saraswati Dental College and Hospital, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iram","family":"Rizvi","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Saraswati Dental College and Hospital, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2019,9,24]]},"reference":[{"key":"key-10.4103\/1305-7456.195160-1","first-page":"76","volume-title":"Morphometric study of the root anatomy in furcation area of mandibular first molars","author":"Marcaccini","year":"2012","journal-title":"J Appl Oral Sci"},{"key":"key-10.4103\/1305-7456.195160-2","first-page":"103","volume-title":"A systematic review of guided tissue regeneration for periodontal furcation defects.What is the effect of guided tissue regeneration compared with surgical debridement in the treatment of furcation defects?","author":"Jepsen","year":"2002","journal-title":"J Clin Periodontol"},{"key":"key-10.4103\/1305-7456.195160-3","first-page":"342","volume-title":"Clinical evaluation of HTR polymer bone replacement grafts in human mandibular Class II molar furcations","author":"Yukna","year":"1994","journal-title":"J Periodontol"},{"key":"key-10.4103\/1305-7456.195160-4","first-page":"107","volume-title":"Evaluation of the relative efficacy of autologous platelet rich plasma in combination with \u03b2-TCP alloplast versus an alloplast alone in the treatment of human periodontal intrabony defects.A clinical and radiological study","author":"Saini","year":"2011","journal-title":"Indian J Dent Res","ISSN":"http:\/\/id.crossref.org\/issn\/0970-9290","issn-type":"print"},{"key":"key-10.4103\/1305-7456.195160-5","first-page":"749","volume-title":"Ten-year results following treatment of intrabony defects with an enamel matrix protein derivative combined with either a natural bone mineral or a \u00df-tricalcium phosphate","author":"D\u00f6ri","year":"2013","journal-title":"J Periodontol"},{"key":"key-10.4103\/1305-7456.195160-6","doi-asserted-by":"crossref","unstructured":"Das S, Jhingran R, Bains VK, Madan R, Srivastava R, Rizvi I. 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