{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T17:27:07Z","timestamp":1786728427749,"version":"build-2736575974"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,4]]},"abstract":"\n Multiple myeloma (MM) is a disease of the elderly. Renal failure is a common complication in MM. In this study, we evaluated clinical and laboratory parameters that might contribute to the recovery of renal function in geriatric MM patients. Twenty-five geriatric patients aged >65 years were retrospectively compared with 20 patients aged <65 years with a diagnosis of MM and renal failure between October 2016 and October 2019. Variables that might be associated with the discontinuation of dialysis in these patients were examined in the 6 months of follow-up after the diagnosis. Among the geriatric patients aged >65 years, 100% remained on regular hemodialysis (HD) at the end of the follow-up period in contrast to eight patients (40%) in the younger group, and this was statistically significant\n P<\/jats:italic>\n = 0.001. We have noticed that geriatric patients who required maintenance HD had lower mean hemoglobin concentrations (\n P<\/jats:italic>\n = 0.02), and higher mean serum calcium (\n P<\/jats:italic>\n = 0.03). Other factors were statistically insignificant. Our study showed that age of >65 years, hemoglobin levels, and serum calcium were significantly different between the group who recovered from renal failure and those who required a continuation of HD, but none was an independent prognostic factor for predicting the probability of recovery from severe renal failure and discontinuation of HD in both groups studied.\n <\/jats:p>","DOI":"10.4103\/1319-2442.384182","type":"journal-article","created":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T04:44:50Z","timestamp":1692679490000},"page":"S105-S110","source":"Crossref","is-referenced-by-count":0,"title":["Factors Affecting the Recovery of Renal Function in Geriatric Multiple Myeloma Patients after Hemodialysis"],"prefix":"10.4103","volume":"33","author":[{"given":"Rabab M.","family":"Ahmed","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Faculty of Medicine, Cairo University, Cairo, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noha M.","family":"El Husseiny","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Faculty of Medicine, Cairo University, Cairo, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,8,22]]},"reference":[{"key":"R1-20230915","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1097\/CCO.0000000000000395","article-title":"EHA SWG on \u2018Aging and Hematology\u2019. Elderly patients with multiple myeloma: Towards a frailty approach?","volume":"29","author":"Zweegman","year":"2017","journal-title":"Curr Opin Oncol"},{"key":"R2-20230915","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1111\/j.1600-0609.2009.01318.x","article-title":"Detection of renal impairment as one specific comorbidity factor in multiple myeloma: Multicenter study in 198 consecutive patients","volume":"83","author":"Kleber","year":"2009","journal-title":"Eur J Haematol"},{"key":"R4-20230915","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1093\/ndt\/gfp488","article-title":"Presentation and survival of patients with severe acute kidney injury and multiple myeloma: A 20-year experience from a single centre","volume":"25","author":"Haynes","year":"2010","journal-title":"Nephrol Dial Transplant"},{"key":"R5-20230915","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1038\/leu.2008.131","article-title":"Pathogenesis and treatment of renal failure in multiple myeloma","volume":"22","author":"Dimopoulos","year":"2008","journal-title":"Leukemia"},{"key":"R6-20230915","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1016\/j.ejim.2014.06.023","article-title":"Severe acute kidney injury and multiple myeloma: Evaluation of kidney and patient prognostic factors","volume":"25","author":"Rodrigues","year":"2014","journal-title":"Eur J Intern Med"},{"key":"R7-20230915","first-page":"722","article-title":"Clinical research about risk factors and reversible predictors in renal impairment due to multiple myeloma","volume":"23","author":"Liu","year":"2015","journal-title":"Zhongguo Shi Yan Xue Ye Xue Za Zhi"},{"key":"R8-20230915","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1053\/j.ajkd.2003.08.040","article-title":"Light chain deposition disease with renal involve-ment: Clinical characteristics and prognostic factors","volume":"42","author":"Pozzi","year":"2003","journal-title":"Am J Kidney Dis"},{"key":"R9-20230915","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1093\/ndt\/13.6.1438","article-title":"Long-term outcome according to renal histological lesions in 118 patients with monoclonal gammopathies","volume":"13","author":"Montseny","year":"1998","journal-title":"Nephrol Dial Transplant"},{"key":"R10-20230915","doi-asserted-by":"crossref","first-page":"c28","DOI":"10.1159\/000319644","article-title":"Factors associated with recovery of renal function in patients with multiple myeloma who were treated with hemodialysis","volume":"117","author":"Katagiri","year":"2011","journal-title":"Nephron Clin Pract"}],"container-title":["Saudi Journal of Kidney Diseases and Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/1319-2442.384182","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T16:26:54Z","timestamp":1786724814000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/1319-2442.384182"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4]]},"references-count":9,"journal-issue":{"issue":"Suppl 2","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/1319-2442.384182","relation":{},"ISSN":["1319-2442","2320-3838"],"issn-type":[{"value":"1319-2442","type":"print"},{"value":"2320-3838","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4]]}}}