{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T17:27:07Z","timestamp":1786728427307,"version":"build-2736575974"},"reference-count":31,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:p>To bridge the gap between demand and supply of organs, deceased donors with extreme ages can be utilized. The object of this study was to compare elderly with non-elderly donors and to assess the predictors of organ utilization or wastage. This was a retrospective chart analysis. Univariate and multivariate logistic regression analysis of cohorts was carried out to predict organ utilization or wastage. Of the 716 deceased donors, 16.2% were elderly (\u226560 years) and 83.8% were not elderly (\u226459 years). Donors in the elderly cohort were more likely to be diabetic, hypertensive, overweight, and smokers compared with non-elderly donors. They had deranged terminal creatinine and succumbed to cerebrovascular accident or intracerebral hemorrhage. They had a high kidney donor risk index (KDRI) of 1.83 \u00b1 0.46. Those in the younger donor cohort, were more likely to have succumbed to road traffic accident-associated traumatic brain injury, were subjected to more efforts to revive them in the intensive care unit via cardiopulmonary resuscitation, had deranged liver function tests, and had a KDRI of 0.93 \u00b1 0.28. The kidney discard rate (KDR) and liver discard rate (LDR) in the elderly donors was 50% and 8.6%, respectively (vis-a-vis the non-elderly at 13.3 % and 7.5%). The KDR was significantly higher than the LDR in elderly donors. The main reason for this was the high number of \u201cmarginal kidneys\u201d. We revealed that elderly donors formed a significant proportion of deceased donors. The utilization of the liver from deceased donors was more frequent compared with the kidney.<\/jats:p>","DOI":"10.4103\/1319-2442.384192","type":"journal-article","created":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T04:44:50Z","timestamp":1692679490000},"page":"S231-S240","source":"Crossref","is-referenced-by-count":0,"title":["Is Age a Limitation for Organ Donation? A Comparison of Elderly and Non-elderly Donors in a Deceased Donor Organ Transplantation Program from South India"],"prefix":"10.4103","volume":"33","author":[{"given":"Banigallapati Vijay","family":"Kiran","sequence":"first","affiliation":[{"name":"Department of Nephrology, Nizam's Institute of Medical Sciences, Hyderabad, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kalidindi Raja","family":"Karthik","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Nizam's Institute of Medical Sciences, Hyderabad, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guditi","family":"Swarnalatha","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Nizam's Institute of Medical Sciences, Hyderabad, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanduri","family":"Gangadhar","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Nizam's Institute of Medical Sciences, Hyderabad, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sree Bhushan","family":"Raju","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Nizam's Institute of Medical Sciences, Hyderabad, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bhrugumalla","family":"Sukanya","sequence":"additional","affiliation":[{"name":"Department of Medical Gastroenterology, Nizam's Institute of Medical Sciences, Hyderabad, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nagari","family":"Beerappa","sequence":"additional","affiliation":[{"name":"Department of Surgical Gastroenterology, Nizam's Institute of Medical Sciences, Hyderabad, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,8,22]]},"reference":[{"key":"R1-20230915","first-page":"1754","article-title":"Effect of donor age and sex on the outcome of liver transplantation","volume":"22","author":"Marino","year":"1995","journal-title":"Hepatology"},{"key":"R2-20230915","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1093\/ndt\/14.4.930","article-title":"Donor age and delayed graft function as predictors of renal allograft survival in rejection-free patients","volume":"14","author":"Moreso","year":"1999","journal-title":"Nephrol Dial Transplant"},{"key":"R3-20230915","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0955-470X(97)80037-7","article-title":"The expanded donor","volume":"11","author":"Kauffman","year":"1997","journal-title":"Transplantation Reviews"},{"key":"R4-20230915","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1053\/rr.2000.6113","article-title":"Expanded criteria donors: attempts to increase the renal transplant donor pool","volume":"7","author":"Mandal","year":"2000","journal-title":"Adv Ren Replace Ther"},{"key":"R5-20230915","first-page":"46","article-title":"Utilization of expanded criteria donors in liver transplantation","volume":"4","year":"2013","journal-title":"Int J Organ Transplant Med"},{"key":"R6-20230915","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1016\/j.healun.2004.08.012","article-title":"Predictors of quality of life at 5 to 6 years after heart transplantation","volume":"24","author":"Grady","year":"2005","journal-title":"J Heart Lung Transplant"},{"key":"R7-20230915","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1097\/00007890-200003150-00020","article-title":"A comparison of the effects of dialysis and renal transplantation on the survival of older uremic patients","volume":"69","author":"Johnson","year":"2000","journal-title":"Transplantation"},{"key":"R8-20230915","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1681\/ASN.V123589","article-title":"Survival in recipients of marginal cadaveric donor kidneys compared with other recipients and wait-listed transplant candidates","volume":"12","author":"Ojo","year":"2001","journal-title":"J Am Soc Nephrol"},{"key":"R9-20230915","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1034\/j.1600-6143.2002.20713.x","article-title":"Evaluation of the Eurotransplant Senior Program. 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