{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:20:20Z","timestamp":1787772020727,"version":"build-2784847793"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023]]},"abstract":"<jats:p>Fibrillary glomerulonephritis (FGN) is a rare glomerular disorder characterized by the deposition of randomly arranged fibrils in the mesangium and the glomerular basement membrane. Clinical features include massive albuminuria, hematuria, high blood pressure, and kidney failure. Usually, the renal prognosis is not favorable, with evolution to end-stage renal disease in approximately 50% of cases. Recent studies in proteomics have identified a member of the heat shock protein family, also called DNAJB9, which is deposited in the glomerulus of patients with FGN and is not present in other diseases, such as amyloidosis or immunotactoid glomerulopathy. These findings are the first step to clarify the pathogenesis of this disease and could facilitate its diagnosis. Hence, we present a case of FGN with mild albuminuria at baseline and discuss the usefulness of this novel biomarker for diagnosing this group of patients.<\/jats:p>","DOI":"10.4103\/1319-2442.397209","type":"journal-article","created":{"date-parts":[[2024,3,9]],"date-time":"2024-03-09T00:55:51Z","timestamp":1709945751000},"page":"458-461","source":"Crossref","is-referenced-by-count":0,"title":["A Case Report of Fibrillary Glomerulonephritis with Mild Albuminuria: A Viewpoint on Proteomics"],"prefix":"10.4103","volume":"34","author":[{"given":"Xavier Enrique","family":"Guerra-Torres","sequence":"first","affiliation":[{"name":"Nephrology Section, Hospital Universitario Pr\u00edncipe de Asturias, Alcal\u00e1 de Henares, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,3,11]]},"reference":[{"key":"R1-20240314","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.1046\/j.1523-1755.2003.00853.x","article-title":"Fibrillary and immunotactoid glomerulonephritis: Distinct entities with different clinical and pathologic features","volume":"63","author":"Rosenstock","year":"2003","journal-title":"Kidney Int"},{"key":"R2-20240314","doi-asserted-by":"crossref","first-page":"775","DOI":"10.2215\/CJN.08300910","article-title":"Fibrillary glomerulonephritis: A report of 66 cases from a single institution","volume":"6","author":"Nasr","year":"2011","journal-title":"Clin J Am Soc Nephrol"},{"key":"R3-20240314","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1053\/j.ajkd.2013.03.031","article-title":"Longterm kidney disease outcomes in fibrillary glomerulonephritis: A case series of 27 patients","volume":"62","author":"Javaugue","year":"2013","journal-title":"Am J Kidney Dis"},{"key":"R4-20240314","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1038\/ki.2008.577","article-title":"Long-term outcome of kidney transplantation in patients with fibrillary glomerulonephritis or monoclonal gammopathy with fibrillary deposits","volume":"75","author":"Czarnecki","year":"2009","journal-title":"Kidney Int"},{"key":"R5-20240314","doi-asserted-by":"crossref","first-page":"157","DOI":"10.4103\/0971-4065.200521","article-title":"Fibrillary glomerulonephritis presenting as crescentic glomerulonephritis","volume":"27","author":"Shah","year":"2017","journal-title":"Indian J Nephrol"},{"key":"R6-20240314","doi-asserted-by":"crossref","first-page":"114","DOI":"10.5414\/CN108667","article-title":"A case of mistaken identity: Fibrillary glomerulonephritis masquerading as crescentic anti-glomerular basement membrane disease","volume":"85","author":"Thomas","year":"2016","journal-title":"Clin Nephrol"},{"key":"R7-20240314","doi-asserted-by":"crossref","first-page":"915","DOI":"10.2215\/CJN.07030712","article-title":"Laser microdissection and proteomic analysis of amyloidosis, cryoglobulinemic GN, fibrillary GN, and immunotactoid glomerulopathy","volume":"8","author":"Sethi","year":"2013","journal-title":"Clin J Am Soc Nephrol"},{"key":"R8-20240314","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1681\/ASN.2017030306","article-title":"DnaJ heat shock protein family B member 9 is a novel biomarker for fibrillary GN","volume":"29","author":"Dasari","year":"2018","journal-title":"J Am Soc Nephrol"}],"container-title":["Saudi Journal of Kidney Diseases and Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/1319-2442.397209","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T18:25:51Z","timestamp":1787768751000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/1319-2442.397209"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023]]},"references-count":8,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.4103\/1319-2442.397209","relation":{},"ISSN":["1319-2442","2320-3838"],"issn-type":[{"value":"1319-2442","type":"print"},{"value":"2320-3838","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023]]}}}