{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T08:52:22Z","timestamp":1791535942053,"version":"4.3.4"},"reference-count":16,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background\/Aim:<\/jats:title>\n                    <jats:p>Intragastric balloon (IGB) is an effective and safe method of weight reduction. However, IGBs have been associated with a high rate of weight regain post removal. Accordingly, ways to improve sustained weight reduction including concomitant treatment with Glucagon-like peptide 1 (GLP-1) agonists have been proposed. This study aims to evaluate the effect of adding Liraglutide to IGB insertion on sustained weight reduction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods:<\/jats:title>\n                    <jats:p>A retrospective analysis of all cases treated with IGB with or without Liraglutide was performed. Outcomes were statistically compared.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      A total of 108 patients were included; 64 were treated with IGB alone and 44 with IGB + Liraglutide. Six months after removing IGB, patients treated with IGB + Liraglutide had a higher mean weight loss post treatment completion (10.2 \u00b1 6.7 vs. 18.5 \u00b1 7.6,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = &lt;0.0001) than those treated with IGB alone. After adjusting for covariates, patients treated with IGB alone demonstrated a higher mean body weight loss at the time of IGB removal (coefficient 7.71, 95% CI = 4.78\u201310.63), and a higher odds of treatment success 6 months post IGB removal (OR = 5.74, 95% CI = 1.79\u2013188.42). Baseline body mass index appeared to be a significant predictor of mean body weight loss at the time of balloon removal.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Adding Liraglutide to IGB does not appear to decrease the risk of weight regain 6 months post IGB removal.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/1319-3767.203362","type":"journal-article","created":{"date-parts":[[2023,3,29]],"date-time":"2023-03-29T06:55:36Z","timestamp":1680072936000},"page":"117-122","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":33,"title":["Does Combining Liraglutide with Intragastric Balloon Insertion Improve Sustained Weight Reduction?"],"prefix":"10.4103","volume":"23","author":[{"given":"Mahmoud M.","family":"Mosli","sequence":"first","affiliation":[{"name":"Department of Medicine, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moaiad","family":"Elyas","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Saad Specialist Hospital, Al-Khobar, Kingdom of Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20250523","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1016\/S0140-6736(16)30054-X","article-title":"Collaboration NCDRF. 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