{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T20:32:42Z","timestamp":1786739562613,"version":"build-2736575974"},"reference-count":7,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>\n                      We present a rare case of Lamellar Ichthyosis with bilateral ectropion with left sided corneal ulcer with descemetocele in a four-month-old female child, the youngest ever reported. Ichthyosis is a group of skin disorders characterized by the presence of fish-like scales all over the body (Mushriff, 2016; Turgut\n                      <jats:italic toggle=\"yes\">et al<\/jats:italic>\n                      ., 2009). Lamellar Ichthyosis is a rare congenital condition with incidence of 1 in 100,000 (Conditions), affecting males and females equally. Inheritance is Autosomal Recessive (Conditions). It involves generalized body as a collodion baby at birth; once the membrane sheds, patient develops large, thick, brown, pasted scales associated with ectropion, eclabium, scarring alopecia, plantar and palmar hyperkeratosis (Mushriff, 2016). Mild cases are managed with hydration, lubrication and keratolytic-agents (Mushriff, 2016). Severe cases are treated with Oral Retinoid. Proper lubrication and patching of eyes with timely management of ectropion to prevent the exposure keraopathy and related complications are needed in such cases. Secondary infections can lead to vision threatening complications, so child with ichthyosis should be under Ophthalmic observation for early needed interventions.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/1319-4534.301289","type":"journal-article","created":{"date-parts":[[2020,11,21]],"date-time":"2020-11-21T05:59:09Z","timestamp":1605938349000},"page":"59-61","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Corneal ulcer secondary to ectropion in lamellar Ichthyosis"],"prefix":"10.4103","volume":"34","author":[{"given":"Sayali S.","family":"Bhedasgaonkar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Snehal U.","family":"Nadkarni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-13-20240830","first-page":"2","article-title":"Bilateral ectropion in lamellar ichthyosis: a rare congenital condition","volume":"4","author":"Mushriff","year":"2016","journal-title":"Adv Ophthalmol Vis Syst"},{"key":"R2-13-20240830","doi-asserted-by":"crossref","first-page":"611","DOI":"10.2147\/OPTH.S8407","article-title":"Spontaneous corneal perforation in a patient with lamellar ichthyosis and dry eye","volume":"3","author":"Turgut","year":"2009","journal-title":"Clin Ophthalmol"},{"key":"R3-13-20240830","first-page":"1895","article-title":"Genetics home reference lamellar ichthyosis 4 Cruz AAV, Menezes FAH, Chaves R, Pinto Coelho R, Velasco EF, Kikuta H Eyelid abnormalities in lamellar ichthyoses","volume":"107","author":"Conditions","year":"2000","journal-title":"Ophthalmology"},{"key":"R4-13-20240830","doi-asserted-by":"crossref","first-page":"1895","DOI":"10.1016\/S0161-6420(00)00333-X","article-title":"Eyelid abnormalities in lamellar ichthyoses","volume":"107","author":"Cruz","year":"2000","journal-title":"Ophthalmology"},{"key":"R6-13-20240830","first-page":"157","article-title":"Bilateral severe ectropion and mature cataract in lamellar ichthyosis","volume":"6","author":"Lone","year":"2004","journal-title":"JK Sci"},{"key":"R7-13-20240830","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1038\/ng0395-279","article-title":"Mutations in the gene for transglutaminase 1 in autosomal recessive lamellar ichthyosis","volume":"9","author":"Russell","year":"1995","journal-title":"Nat Genet"},{"key":"R8-13-20240830","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/IOP.0b013e3181b8e0d4","article-title":"Maternal skin allograft for cicatricial ectropion in congenital icthyosis","volume":"26","author":"Das","year":"2010","journal-title":"Ophthalmic Plast Reconstr Surg"}],"container-title":["Saudi Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/1319-4534.301289","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T19:30:02Z","timestamp":1786735802000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/1319-4534.301289"}},"subtitle":["A rare congenital disorder"],"short-title":[],"issued":{"date-parts":[[2020,1]]},"references-count":7,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020]]}},"URL":"https:\/\/doi.org\/10.4103\/1319-4534.301289","relation":{},"ISSN":["1319-4534"],"issn-type":[{"value":"1319-4534","type":"print"}],"subject":[],"published":{"date-parts":[[2020,1]]}}}