{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:30:26Z","timestamp":1787772626400,"version":"build-2784847793"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>To describe an unusual case of retinoblastoma in adult Saudi. A 21-year-old Saudi male developed acute unilateral visual loss due to a large intraocular lesion in his left eye. Within five days of presentation, the tumor enlarged rapidly causing angle closure glaucoma and orbital cellulitis like picture. The patient underwent enucleation and the histopathology specimen confirmed the presence of an undifferentiated type tumor cell that was consistent with retinoblastoma with choroidal and optic nerve invasion. Retinoblastoma should be considered in the differential diagnosis of an intraocular mass in adults. To the best of our knowledge, this is the first reported case of an adult presentation of retinoblastoma in Saudi patient.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/1319-4534.305046","type":"journal-article","created":{"date-parts":[[2021,3,9]],"date-time":"2021-03-09T02:54:58Z","timestamp":1615258498000},"page":"136-138","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Adult presentation of retinoblastoma in Saudi patient"],"prefix":"10.4103","volume":"34","author":[{"given":"Saba","family":"Al Rashaed","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sahar M.","family":"Elkhamary","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osama","family":"Al Sheikh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saleh","family":"Al Mesfer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hassan","family":"Al-Dhibi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azza","family":"Al Maktabi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-14-20240830","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1001\/archopht.1980.01020040056003","article-title":"Incidence of retinoblastoma in the United States","volume":"98","author":"Pendergrass","year":"1980","journal-title":"Arch Ophthalmol"},{"key":"R2-14-20240830","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1136\/bjo.3.8.337","article-title":"A case of bilateral glioma of the retina in a girl twenty years of age in which the second eye was excised after an interval of nearly eighteen years","volume":"3","author":"Maghy","year":"1919","journal-title":"Br J Ophthalmol"},{"key":"R3-14-20240830","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/S0008-4182(05)80032-8","article-title":"Retinoblastoma in an adult: Case report and literature review","volume":"40","author":"Odashiro","year":"2005","journal-title":"Can J Ophthalmol"},{"key":"R4-14-20240830","doi-asserted-by":"crossref","first-page":"358","DOI":"10.4103\/0974-9233.142280","article-title":"Failure of globe conservation in a case of adult onset retinoblastoma","volume":"21","author":"Khetan","year":"2014","journal-title":"Middle East Afr J Ophthalmol"},{"key":"R5-14-20240830","doi-asserted-by":"crossref","first-page":"87","DOI":"10.3109\/13816810.2012.718028","article-title":"Late recurrence of tumor necessitating enucleation in an adult onset retinoblastoma","volume":"34","author":"Khetan","year":"2013","journal-title":"Ophthalmic Genet"},{"key":"R7-14-20240830","first-page":"26","article-title":"Retinoblatoma in older children","volume":"6","author":"Karcioglu","year":"2002","journal-title":"JAAPOS"},{"key":"R8-14-20240830","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1016\/S0161-6420(87)33537-7","article-title":"Prevalence and mechanism of secondary intraocular pressure elevation in eyes with intraocular tumors","volume":"94","author":"Shields","year":"1987","journal-title":"Ophthalmology"},{"key":"R9-14-20240830","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/j.jaapos.2013.02.009","article-title":"Retinoblastoma presenting with orbital cellulitis","volume":"17","author":"Walinjkar","year":"2013","journal-title":"AAPOS"},{"key":"R10-14-20240830","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.survophthal.2017.01.010","article-title":"Necrotic intraocular retinoblastoma associated with orbital cellulitis","volume":"63","author":"Nalci","year":"2018","journal-title":"Surv Ophthalmol"},{"key":"R11-14-20240830","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.1001\/archopht.1996.01100140602013","article-title":"Immunocytochemical features of retinoblastoma in an adult","volume":"114","author":"Nork","year":"1996","journal-title":"Arch Ophthalmol"}],"container-title":["Saudi Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/1319-4534.305046","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:06:38Z","timestamp":1787771198000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/1319-4534.305046"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020]]}},"URL":"https:\/\/doi.org\/10.4103\/1319-4534.305046","relation":{},"ISSN":["1319-4534"],"issn-type":[{"value":"1319-4534","type":"print"}],"subject":[],"published":{"date-parts":[[2020,4]]}}}