{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T20:31:23Z","timestamp":1786739483179,"version":"build-2736575974"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>Brown-McLean syndrome not reported in association with homocystinuria and generally occurs in patients with long-term aphakia. Presented as peripheral corneal edema with central clear cornea tends to spare vision without the need of any surgical intervention. The purpose of reporting such a rare condition as a first case of Brown-McLean syndrome associated with systemic disease of homocystinuria. Brown-McLean Syndrome in a patient with homocystinuria generally occurs in patients with long-term aphakia after different modalities of surgical intervention. A high clinical suspicion and regular follow-up is warranted for patients with systemic diseases who are aphakic or present with a subluxated lens for early intervention and better prognosis if needed.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/1319-4534.322619","type":"journal-article","created":{"date-parts":[[2021,7,28]],"date-time":"2021-07-28T16:04:52Z","timestamp":1627488292000},"page":"300-302","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Brown-Mclean syndrome in an aphakic patient with homocystinuria"],"prefix":"10.4103","volume":"34","author":[{"given":"Saad H.","family":"Alenezi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. M.","family":"Alrefaie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaker O.","family":"Alreshidi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hani B.","family":"ALBalawi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hernan M.","family":"Osorio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-14-20240830","doi-asserted-by":"crossref","first-page":"671","DOI":"10.2147\/OPTH.S96507","article-title":"Brown\u2013McLean syndrome: The role of iridodonesis","volume":"10","author":"Suwan","year":"2016","journal-title":"Clin Ophthalmol"},{"key":"R2-14-20240830","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1136\/bjo.73.6.427","article-title":"Ocular complications in homocystinuria \u2013 Early and late treated","volume":"73","author":"Burke","year":"1989","journal-title":"Br J Ophthalmol"},{"key":"R3-14-20240830","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1159\/000381941","article-title":"Brown-mcLean syndrome in a pediatric patient","volume":"6","author":"Tourkmani","year":"2015","journal-title":"Case Rep Ophthalmol"},{"key":"R4-14-20240830","doi-asserted-by":"crossref","first-page":"76","DOI":"10.3341\/kjo.2016.30.1.76","article-title":"Brown-mcLean syndrome in a patient with hallermann-streiff syndrome","volume":"30","author":"Mohebbi","year":"2016","journal-title":"Korean J Ophthalmol"},{"key":"R5-14-20240830","first-page":"179","article-title":"Brown-mcLean syndrome with keratoconus","volume":"22","author":"Jamil","year":"2012","journal-title":"J Coll Physicians Surg Pak"},{"key":"R6-14-20240830","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1016\/S0886-3350(03)00049-X","article-title":"In vivo confocal microstructural analysis and surgical management of Brown-Mclean syndrome associated with spontaneous crystalline lens luxation","volume":"29","author":"Vote","year":"2003","journal-title":"J Cataract Refract Surg"},{"key":"R7-14-20240830","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1016\/S0002-9394(14)73639-6","article-title":"Clinical findings in Brown-McLean syndrome","volume":"115","author":"Gothard","year":"1993","journal-title":"Am J Ophthalmol"},{"key":"R8-14-20240830","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1016\/S0886-3350(00)00837-3","article-title":"Cataract surgery in a patient with Brown-McLean syndrome","volume":"27","author":"Rutzen","year":"2001","journal-title":"J Cataract Refract Surg"},{"key":"R9-14-20240830","doi-asserted-by":"crossref","first-page":"6","DOI":"10.3109\/08820538.2011.588647","article-title":"Corneal endothelium in Brown-McLean syndrome: In-vivo confocal microscopy finding","volume":"27","author":"Lim","year":"2012","journal-title":"Semin Ophthalmol"},{"key":"R10-14-20240830","doi-asserted-by":"crossref","first-page":"bcr2013201280","DOI":"10.1136\/bcr-2013-201280","article-title":"Brown-McLean syndrome","volume":"2013","author":"Kam","year":"2013","journal-title":"BMJ Case Rep"},{"key":"R11-14-20240830","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1038\/eye.1992.106","article-title":"Peripheral corneal oedema following cataract extraction (Brown-McLean syndrome)","volume":"6","author":"Tuft","year":"1992","journal-title":"Eye (Lond"},{"key":"R12-14-20240830","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1038\/sj.eye.6702244","article-title":"Atypical clinical presentations of Brown-McLean syndrome","volume":"21","author":"Almousa","year":"2007","journal-title":"Eye (Lond"}],"container-title":["Saudi Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/1319-4534.322619","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T19:29:18Z","timestamp":1786735758000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/1319-4534.322619"}},"subtitle":["The first reported case in Middle East"],"short-title":[],"issued":{"date-parts":[[2020,10]]},"references-count":12,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020]]}},"URL":"https:\/\/doi.org\/10.4103\/1319-4534.322619","relation":{},"ISSN":["1319-4534"],"issn-type":[{"value":"1319-4534","type":"print"}],"subject":[],"published":{"date-parts":[[2020,10]]}}}