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A presurgical staging 18-fluoro-deoxyglucose-positron emission tomography\/computed tomography (FDG-PET\/CT) found increased metabolic activity in the cervical, axillary, mediastinal, supraclavicular, para-aortic and mesenteric lymph nodes. This pattern of metastasis was very unusual for lynch syndrome associated colon adenocarcinoma and the involvement of those lymph nodes resembles the pattern of spread of lymphoma. He underwent right hemicolectomy and he was subsequently treated with 12 cycles of folinic acid (leucovorin), fluorouracil (5-FU), irinotecan. A restaging FDG-PET\/CT at the end of the chemotherapy showed interval decrease in size and metabolic activity in the affected lymph nodes. FDG-PET\/CT is a useful imaging modality in following-up the treatment response in colon adenocarcinoma.<\/jats:p>","DOI":"10.4103\/1450-1147.161728","type":"journal-article","created":{"date-parts":[[2015,7,29]],"date-time":"2015-07-29T06:18:53Z","timestamp":1438150733000},"page":"222-224","source":"Crossref","is-referenced-by-count":1,"title":["Lynch Syndrome Associated Colon Adenocarcinoma Resembling Lymphoma on Fluoro-Deoxyglucose-Positron Emission Tomography\/Computed Tomography"],"prefix":"10.1055","volume":"14","author":[{"given":"Carina","family":"Aparici","sequence":"additional","affiliation":[{"name":"Department of Radiology, University of California, San Francisco, CA 94143"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aung","family":"Win","sequence":"additional","affiliation":[{"name":"Department of Radiology, San Francisco VA Medical Center, San Francisco, CA 94121, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2022,5,21]]},"reference":[{"key":"key-10.4103\/1450-1147.161728-1","first-page":"12420","volume-title":"Early-onset colorectal cancer: A sporadic or inherited disease?","author":"Stigliano","year":"2014","journal-title":"World J Gastroenterol"},{"key":"key-10.4103\/1450-1147.161728-2","first-page":"106","volume-title":"Colon cancer","author":"Labianca","year":"2010","journal-title":"Crit Rev Oncol Hematol"},{"key":"key-10.4103\/1450-1147.161728-3","first-page":"7","volume-title":"Contiguous pattern spreading in patients with Hodgkin\u2032s disease","author":"Roth","year":"1998","journal-title":"Radiother Oncol"},{"key":"key-10.4103\/1450-1147.161728-4","first-page":"1624","volume-title":"Metastatic patterns in adenocarcinoma","author":"Hess","year":"2006","journal-title":"Cancer"},{"key":"key-10.4103\/1450-1147.161728-5","first-page":"164","volume-title":"Solitary mediastinal lymph node recurrence after curative resection of colon cancer","author":"Matsuda","year":"2014","journal-title":"World J Gastrointest Surg"},{"key":"key-10.4103\/1450-1147.161728-6","first-page":"170432","volume-title":"Current hypotheses on how microsatellite instability leads to enhanced survival of Lynch Syndrome patients","author":"Drescher","year":"2010","journal-title":"Clin Dev Immunol"},{"key":"key-10.4103\/1450-1147.161728-7","first-page":"2553","volume-title":"Association between methylation in mismatch repair genes, V600E BRAF mutation and microsatellite instability in colorectal cancer patients","author":"Rasuck","year":"2012","journal-title":"Mol Biol Rep"},{"key":"key-10.4103\/1450-1147.161728-8","first-page":"353","volume-title":"Guidelines for the clinical management of Lynch syndrome (hereditary non-polyposis cancer)","author":"Vasen","year":"2007","journal-title":"J Med Genet"},{"key":"key-10.4103\/1450-1147.161728-9","first-page":"18","volume-title":"Prospective assessment of primary rectal cancer response to preoperative radiation and chemotherapy using 18-fluorodeoxyglucose positron emission tomography","author":"Guillem","year":"2000","journal-title":"Dis Colon Rectum"},{"key":"key-10.4103\/1450-1147.161728-10","first-page":"1560","volume-title":"What is the most accurate whole-body imaging modality for assessment of local and distant recurrent disease in colorectal cancer.A meta-analysis: Imaging for recurrent colorectal cancer?","author":"Maas","year":"2011","journal-title":"Eur J Nucl Med Mol Imaging"}],"container-title":["World Journal of Nuclear Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.4103\/1450-1147.161728.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,21]],"date-time":"2022-05-21T22:30:38Z","timestamp":1653172238000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.4103\/1450-1147.161728"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,7]]},"references-count":10,"journal-issue":{"issue":"03","published-online":{"date-parts":[[2022,5,21]]},"published-print":{"date-parts":[[2015,7]]}},"URL":"https:\/\/doi.org\/10.4103\/1450-1147.161728","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["1450-1147","1607-3312"],"issn-type":[{"value":"1450-1147","type":"print"},{"value":"1607-3312","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,7]]}}}