{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T23:38:50Z","timestamp":1780616330145,"version":"3.54.1"},"reference-count":19,"publisher":"Georg Thieme Verlag KG","issue":"03","license":[{"start":{"date-parts":[[2022,5,18]],"date-time":"2022-05-18T00:00:00Z","timestamp":1652832000000},"content-version":"vor","delay-in-days":1782,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World J Nucl Med"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:p>To evaluate the accuracy of fluorodeoxyglucose positron emission tomography\/computed tomography (PET\/CT) in staging and restaging of patients with mucosal melanomas (MM) of head and neck. Patients who underwent PET\/CT at our institution, with a biopsy proven diagnosis of MM of the head and neck between March 2006 and December 2013 were included in the study. Nineteen patients with MM of the nasal cavity, paranasal sinuses, and oral cavity were included, of which 12 were for staging and seven for restaging. PET\/CT had 100% sensitivity (SN), specificity (SP), positive predictive value (PPV), and negative predictive value (NPV) for detection of the primary. SN of 91.7%, SP of 100%, PPV of 100%, and NPV of 87.5% were seen for nodal metastases. For distant metastases, SN of 85.7%, SP of 100%, PPV of 100%, and NPV of 92.3% were noted. The disease was upstaged from loco-regional to metastatic in 32% leading to treatment change in 25% in the staging group and 43% in the restaging group. PET\/CT demonstrates good overall accuracy in evaluation of patients with MM of the head and neck. The main strength of PET\/CT lies in detection of distant metastatic disease due to extended whole-body field of view.<\/jats:p>","DOI":"10.4103\/1450-1147.207274","type":"journal-article","created":{"date-parts":[[2017,5,30]],"date-time":"2017-05-30T06:23:33Z","timestamp":1496125413000},"page":"197-201","source":"Crossref","is-referenced-by-count":16,"title":["Positron emission tomography in mucosal melanomas of head and neck: Results from a South Asian tertiary cancer care center"],"prefix":"10.1055","volume":"16","author":[{"given":"Archi","family":"Agrawal","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine and Molecular Imaging, Tata Memorial Hospital, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gouri","family":"Pantvaidya","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology, Tata Memorial Hospital, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vedang","family":"Murthy","sequence":"additional","affiliation":[{"name":"Department of Radiotherapy, Tata Memorial Hospital, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kumar","family":"Prabhash","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Tata Memorial Hospital, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Munita","family":"Bal","sequence":"additional","affiliation":[{"name":"Department of Pathology, Tata Memorial Hospital, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nilendu","family":"Purandare","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine and Molecular Imaging, Tata Memorial Hospital, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sneha","family":"Shah","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine and Molecular Imaging, Tata Memorial Hospital, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Venkatesh","family":"Rangarajan","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine and Molecular Imaging, Tata Memorial Hospital, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2022,5,18]]},"reference":[{"key":"key-10.4103\/1450-1147.207274-1","first-page":"235","volume-title":"The distribution of melanocytes in the leptomeninges of the human brain","author":"Goldgeier","year":"1984","journal-title":"J Invest Dermatol"},{"key":"key-10.4103\/1450-1147.207274-2","first-page":"192","volume-title":"Experience with mucosal melanoma of the nose and paranasal sinuses","author":"Bridger","year":"2005","journal-title":"ANZ J Surg"},{"key":"key-10.4103\/1450-1147.207274-3","first-page":"594","volume-title":"Sinonasal tract and nasopharyngeal melanomas: A clinicopathologic study of 115 cases with a proposed staging system","author":"Thompson","year":"2003","journal-title":"Am J Surg Pathol"},{"key":"key-10.4103\/1450-1147.207274-4","first-page":"1385","volume-title":"Outcome of sinonasal melanoma: Clinical experience and review of the literature","author":"Roth","year":"2010","journal-title":"Head Neck"},{"key":"key-10.4103\/1450-1147.207274-5","first-page":"739","volume-title":"Primary mucosal melanomas: A comprehensive review","author":"Mihajlovic","year":"2012","journal-title":"Int J Clin Exp Pathol"},{"key":"key-10.4103\/1450-1147.207274-6","first-page":"560","volume-title":"(18) FDG-PET\/CT for detecting distant metastases and second primary cancers in patients with head and neck cancer.A meta-analysis","author":"Xu","year":"2011","journal-title":"Oral Oncol"},{"key":"key-10.4103\/1450-1147.207274-7","first-page":"1632","volume-title":"Negative predictive value of surveillance PET\/CT in head and neck squamous cell cancer","author":"McDermott","year":"2013","journal-title":"AJNR Am J Neuroradiol"},{"key":"key-10.4103\/1450-1147.207274-8","first-page":"401","volume-title":"PET-CT in recurrent head neck cancers: A study to evaluate impact on patient management","author":"Pantvaidya","year":"2009","journal-title":"J Surg Oncol"},{"key":"key-10.4103\/1450-1147.207274-9","first-page":"2026","volume-title":"Demographics and treatment trends in sinonasal mucosal melanoma","author":"Gal","year":"2011","journal-title":"Laryngoscope"},{"key":"key-10.4103\/1450-1147.207274-10","doi-asserted-by":"crossref","unstructured":"Moreno MA, Roberts DB, Kupferman ME, DeMonte F, El-Naggar AK, Williams M, et al. 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