{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:33:04Z","timestamp":1787776384199,"version":"build-2784847793"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2016,4]]},"abstract":"<jats:p>A little over 30 cases on co-existing nephrotic syndrome and autosomal dominant polycystic kidney disease (ADPKD) have been reported from different regions of the world since 1957. We present a case report on co-existence of nephrotic syndrome (secondary to lupus nephritis) with ADPKD in a 24-year-old woman from Nigeria. She was positive for anti-double stranded DNA. Renal histology showed International Society of Nephrology\/Renal Pathology Society Class II lupus nephritis. The co-existence of nephrotic syndrome and ADPKD may have been overlooked in Africa in the past. There is a need to screen for nephrotic syndrome in patients with ADPKD among clinicians in the African setting.<\/jats:p>","DOI":"10.4103\/1596-3519.179735","type":"journal-article","created":{"date-parts":[[2016,4,5]],"date-time":"2016-04-05T04:44:10Z","timestamp":1459831450000},"page":"83-86","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["Co-existing autosomal dominant polycystic kidney disease and nephrotic syndrome in a Nigerian patient with lupus nephritis"],"prefix":"10.4103","volume":"15","author":[{"given":"A. A.","family":"Akinbodewa","sequence":"first","affiliation":[{"name":"Kidney Care Centre, University of Medical Sciences, Ondo State, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O. A.","family":"Adejumo","sequence":"additional","affiliation":[{"name":"Kidney Care Centre, University of Medical Sciences, Ondo State, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. O.","family":"Ogunsemoyin","sequence":"additional","affiliation":[{"name":"Department of Radiology, Trauma Centre, University of Medical Sciences, Ondo State, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. A.","family":"Osasan","sequence":"additional","affiliation":[{"name":"Department of Morbid Anatomy, Centre University of Medical Sciences, Ondo State, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O. A.","family":"Adefolalu","sequence":"additional","affiliation":[{"name":"Department of Morbid Anatomy, University of Medical Science, Ondo State, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R2-20250528","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1681\/ASN.V561349","article-title":"Overt proteinuria and microalbuminuria in autosomal dominant polycystic kidney disease","volume":"5","author":"Chapman","year":"1994","journal-title":"J Am Soc Nephrol"},{"key":"R3-20250528","first-page":"1","article-title":"Bilateral polycystic disease of the kidneys; a follow-up of two hundred and eighty-four patients and their families","volume":"328","author":"Dalgaard","year":"1957","journal-title":"Acta Med Scand Suppl"},{"key":"R4-20250528","first-page":"136","article-title":"A rare cause of nephrotic syndrome in autosomal dominant polycystic kidney disease","volume":"2","author":"Wan","year":"2009","journal-title":"NDT Plus"},{"key":"R5-20250528","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.krcp.2012.06.002","article-title":"Laparoscopic biopsy-proven lupus nephritis in autosomal dominant polycystic kidney disease","volume":"31","author":"Park","year":"2012","journal-title":"Kidn Res Clin Pract"},{"key":"R6-20250528","first-page":"1","article-title":"Nephrotic syndrome and autosomal dominant polycystic kidney disease","volume":"0","author":"Visciano","year":"2012","journal-title":"Clin Kidney J"},{"key":"R7-20250528","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1100\/tsw.2011.94","article-title":"Nephrotic syndrome and idiopathic membranous nephropathy associated with autosomal-dominant polycystic kidney disease","volume":"11","author":"Peces","year":"2011","journal-title":"Scientific- World Journal"},{"key":"R8-20250528","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1186\/1752-1947-4-125","article-title":"Autosomal dominant polycystic kidney disease with diffuse proliferative glomerulonephritis\u2014an unusual association: a case report and review of the literature","volume":"4","author":"D\u2019Cruz","year":"2010","journal-title":"J Med Case Rep"},{"key":"R9-20250528","first-page":"243","article-title":"Coexistence of Autosomal Dominant Polycystic Kidney Disease and Amyloidosis in a Patient With Nephrotic-range Proteinuria","volume":"8","author":"Yenigun","year":"2014","journal-title":"IJKD"},{"key":"R10-20250528","first-page":"73","article-title":"Massive proteinuria and autosomal dominant polycystic kidney disease: A rare coincidence","volume":"6","author":"Savaj","year":"2012","journal-title":"Iran J Kidney Dis"}],"container-title":["Annals of African Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/01244624-201615020-00007","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:08:20Z","timestamp":1787774900000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/01244624-201615020-00007"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4]]},"references-count":9,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016]]}},"URL":"https:\/\/doi.org\/10.4103\/1596-3519.179735","relation":{},"ISSN":["1596-3519","0975-5764"],"issn-type":[{"value":"1596-3519","type":"print"},{"value":"0975-5764","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,4]]}}}