{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:44:06Z","timestamp":1787071446177,"version":"build-2736575974"},"reference-count":5,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:p>Colchicine is an alkaloid extracted from autumnal Colchicum plant which is used primarily for its anti-inflammatory therapy effect. Acute intoxication with colchicine is uncommon but often severe and results in multiple visceral organ dysfunctions. The intoxication severity and mortality are directly depending on the ingested dose. The treatment is manly symptomatic. However, the development of specific anti-colchicine immunotherapy would offer a new therapeutic perspective.<\/jats:p>\n                  <jats:p>Authors report a case of a young patient that ingested 40 tablets colchicine, which caused a multiple organ failure and with fatal outcome.<\/jats:p>","DOI":"10.4103\/1658-354x.136629","type":"journal-article","created":{"date-parts":[[2014,7,10]],"date-time":"2014-07-10T08:33:25Z","timestamp":1404981205000},"page":"394-395","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":8,"title":["Fatal colchicine intoxication"],"prefix":"10.4103","volume":"8","author":[{"given":"Smael","family":"Labib","sequence":"first","affiliation":[{"name":"Department of Anesthesia and Intensive Care, University Hospital of Fez, Fez, Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sa\u00efd","family":"Boujraf","sequence":"additional","affiliation":[{"name":"Department of Biophysics and Clinical MRI Methods, Faculty of Medicine of Fez, Fez, Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adnan","family":"Berdai","sequence":"additional","affiliation":[{"name":"Department of Anesthesia and Intensive Care, University Hospital of Fez, Fez, Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustapha","family":"Harandou","sequence":"additional","affiliation":[{"name":"Department of Anesthesia and Intensive Care, University Hospital of Fez, Fez, Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20250926","doi-asserted-by":"crossref","first-page":"385","DOI":"10.3109\/15563650.2013.800876","article-title":"Extracorporeal membrane oxygenation in the treatment of poisoned patients","volume":"51","author":"De Lange","year":"2013","journal-title":"Clin Toxicol (Phila)"},{"key":"R2-20250926","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1111\/j.1749-6632.2009.04674.x","article-title":"Colchicine revisited","volume":"1173","author":"Bhat","year":"2009","journal-title":"Ann N Y Acad Sci"},{"key":"R3-20250926","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1002\/jat.1198","article-title":"Acute oral toxicity of colchicine in rats: Effects of gender, vehicle matrix and pre-exposure to lipopolysaccharide","volume":"27","author":"Wiesenfeld","year":"2007","journal-title":"J Appl Toxicol"},{"key":"R4-20250926","doi-asserted-by":"crossref","first-page":"739","DOI":"10.3109\/15563650.2011.610146","article-title":"Fatal poisoning in children: Acute colchicine intoxication and new treatment approaches","volume":"49","author":"Ozdemir","year":"2011","journal-title":"Clin Toxicol (Phila)"},{"key":"R5-20250926","first-page":"303","article-title":"Survival case of colchicine intoxication following ingestion of a lethal dose","volume":"23","author":"Usumoto","year":"2010","journal-title":"Chudoku Kenkyu"}],"container-title":["Saudi Journal of Anaesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/01437113-201408030-00019","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:46:15Z","timestamp":1787067975000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/01437113-201408030-00019"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7]]},"references-count":5,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014]]}},"URL":"https:\/\/doi.org\/10.4103\/1658-354x.136629","relation":{},"ISSN":["1658-354X","0975-3125"],"issn-type":[{"value":"1658-354X","type":"print"},{"value":"0975-3125","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,7]]}}}