{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:44:09Z","timestamp":1787071449838,"version":"build-2736575974"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:p>Apert syndrome is an autosomal dominant disease characterized by craniosynostosis, midface hypoplasia and syndactyly. In general, patients present in early childhood for craniofacial reconstruction surgery. Anesthetic implications include difficult airway, airway hyper-reactivity; however, possibility of raised intracranial pressure especially when operating for craniosynostosis and associated congenital heart disease should not be ignored. Most of the cases described in literature talk of management of syndactyly. We describe the successful anesthetic management of a patient of Aperts syndrome with craniosynostosis posted for bicornual strip craniotomy and fronto-orbital advancement in a 5-year-old child.<\/jats:p>","DOI":"10.4103\/1658-354x.136631","type":"journal-article","created":{"date-parts":[[2014,7,10]],"date-time":"2014-07-10T08:33:25Z","timestamp":1404981205000},"page":"399-401","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":7,"title":["Anesthetic management of craniosynostosis repair in patient with Apert syndrome"],"prefix":"10.4103","volume":"8","author":[{"given":"Niraj","family":"Kumar","sequence":"first","affiliation":[{"name":"Department of Neuroanaesthesiology, Neuroscience Centre, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shubhangi","family":"Arora","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashish","family":"Bindra","sequence":"additional","affiliation":[{"name":"Department of Neuroanaesthesiology, Neuroscience Centre, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keshav","family":"Goyal","sequence":"additional","affiliation":[{"name":"Department of Neuroanaesthesiology, Neuroscience Centre, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20250926","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/S0901-5027(05)80544-2","article-title":"New indirect method for estimating the birth prevalence of the Apert syndrome","volume":"21","author":"Cohen","year":"1992","journal-title":"Int J Oral Maxillofac Surg"},{"key":"R2-20250926","first-page":"169","article-title":"Apert's syndrome","volume":"46","author":"Sohi","year":"1980","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"R3-20250926","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1002\/ajmg.1320450618","article-title":"Visceral anomalies in the Apert syndrome","volume":"45","author":"Cohen","year":"1993","journal-title":"Am J Med Genet"},{"key":"R4-20250926","doi-asserted-by":"crossref","first-page":"6","DOI":"10.3109\/00016489409124330","article-title":"Sleep apnea and sleep-related breathing disorders in patients with craniofacial synostosis","volume":"517","author":"Kakitsuba","year":"1994","journal-title":"Acta Otolaryngol Suppl"},{"key":"R5-20250926","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1097\/00006534-199009000-00011","article-title":"Obstructive sleep apnea in Apert's and Pfeiffer's syndromes: More than a craniofacial abnormality","volume":"86","author":"Mixter","year":"1990","journal-title":"Plast Reconstr Surg"},{"key":"R6-20250926","first-page":"328","article-title":"Cervical spine anomalies in the craniosynostosis syndromes","volume":"24","author":"Hemmer","year":"1987","journal-title":"Cleft Palate J"},{"key":"R7-20250926","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1111\/j.1460-9592.2010.03457.x","article-title":"Perioperative complications in children with Apert syndrome: A review of 509 anesthetics","volume":"21","author":"Barnett","year":"2011","journal-title":"Paediatr Anaesth"},{"key":"R8-20250926","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1046\/j.1460-9592.2001.00745.x","article-title":"Respiratory complications during anesthesia in Apert syndrome","volume":"11","author":"Elwood","year":"2001","journal-title":"Paediatr Anaesth"},{"key":"R9-20250926","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1002\/ajmg.1320440121","article-title":"Upper and lower airway compromise in the Apert syndrome","volume":"44","author":"Cohen","year":"1992","journal-title":"Am J Med Genet"},{"key":"R10-20250926","first-page":"603","article-title":"An intraoperative unexpected respiratory problem in a patient with Apert syndrome","volume":"73","author":"Basar","year":"2007","journal-title":"Minerva Anestesiol"}],"updated-by":[{"DOI":"10.4103\/1658-354x.165486","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2015,10,1]],"date-time":"2015-10-01T00:00:00Z","timestamp":1443657600000}}],"container-title":["Saudi Journal of Anaesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/01437113-201408030-00021","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:46:18Z","timestamp":1787067978000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/01437113-201408030-00021"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7]]},"references-count":10,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014]]}},"URL":"https:\/\/doi.org\/10.4103\/1658-354x.136631","relation":{},"ISSN":["1658-354X","0975-3125"],"issn-type":[{"value":"1658-354X","type":"print"},{"value":"0975-3125","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,7]]}}}